Recent content by 111

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    Study to Evaluate SPI-1005 in Adults with Meniere's Disease

    See below link for a US Meniere's trial still recruiting by sound pharmaceuticals. Though this is a Meniere's study the brief summary says- This study will evaluate the safety and efficacy of three dose levels of SPI-1005 compared to placebo on vertigo, tinnitus and sensorineural hearing loss...
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    Autifony Therapeutics Phase II Study for AUT00063, for the Treatment of Hearing Loss and Tinnitus

    Read this to understand what it is and what it has the potential to do http://www.hearingreview.com/2015/06/new-drug-promises-relief-from-tinnitus-epilepsy/
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    Autifony Therapeutics Phase II Study for AUT00063, for the Treatment of Hearing Loss and Tinnitus

    Quite ironic that only in July 2015 they received and extra 8 million in funding, taking it to 23.5 million in total for series A. Charles large made this comment about receiving the funding only in July 2015 - "We are delighted that all Autifony’s investors are supporting us with additional...
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    Autifony Therapeutics Phase II Study for AUT00063, for the Treatment of Hearing Loss and Tinnitus

    You don't need to wait. This link takes you to their own page and you will find all the questions asked, and all the answers that they provided, and that was back on July 16th as well.
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    Identifying and Targeting Possible Tinnitus Genes

    Research similar to this has been conducted already, using side effect network analysis, and the results are in the below link. It is quite an technical read but has some interesting points none the less. If nothing else at least you get a list of all the meds they used for this research and...
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    Autifony Therapeutics Phase II Study for AUT00063, for the Treatment of Hearing Loss and Tinnitus

    Seeing as you got the exact same reply as I got from them, and mine was from Nov 2014, I wouldn't say they were that good at responding either, they are obviously using set templates to reply to questions. I would suggest no one of any significance in the company would be looking at these...
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    Retigabine (Trobalt, Potiga) — General Discussion

    Interestingly enough this company is looking into something to do with GABA and NDMA and says the below on their research program page Discovery Programs We are exploring additional potential products in a variety of CNS disorders based on modulation of both the GABAA and NMDA receptors. In...
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    Autifony Therapeutics Phase II Study for AUT00063, for the Treatment of Hearing Loss and Tinnitus

    Lots of speculation and guessing going on here for sure about time scales, so here is a copy of correspondence I had directly with Autifony during Nov 2014, when I asked a question about time scales for testing. Seeing as this is directly from Autifony I consider it to be useful information and...
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    Autifony Therapeutics Phase II Study for AUT00063, for the Treatment of Hearing Loss and Tinnitus

    See below, they basically allowed Autifony the rights to patented compounds and data in exchange for shares in Autifony GSK takes minority stake in new spin out Autifony Therapeutics 22 August 2011 This press release is intended for business journalists and analysts/investors. Please note...
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    Retigabine (Trobalt, Potiga) — General Discussion

    Given the discussions about all the different Kv channels and what they can and cannot do and what parts they affect, according to peoples opinion anyway, here is an interesting document all about the Kv7 channels. I might have posted this already some time ago, but here it is again anyway...
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    Autifony Therapeutics Phase II Study for AUT00063, for the Treatment of Hearing Loss and Tinnitus

    If you want to invest in them, seeing as they are not self funded, you could invest in imperial innovations which has a 27.5 % share holding in them. The main issue being you are also relying on the other portfolio funds as well to perform, so the price could change depending on other results ...
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    Autifony Therapeutics Phase II Study for AUT00063, for the Treatment of Hearing Loss and Tinnitus

    I posted this link previously some time ago, but they now have more information on their site. Someone else looking at developing another drug to target areas, similar in working, to 063 http://knoppbio.com/research/show.php?2
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    Retigabine (Trobalt, Potiga) — General Discussion

    I posted this link previously some time ago, but they now have more information on their site. Someone else looking at doing a improved version of Trobalt http://knoppbio.com/research/show.php?2
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    Research Going on We Don't Know About?

    I posted this one some time ago, maybe there are others out there we don't know about yet. Have a look and see for yourself what they are looking into developing http://knoppbio.com/research/show.php?2
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    Melatonin Trial Being Conducted in the UK

    Came across this link for a trial to be conducted in the UK, for anyone interested, using Melatonin http://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42015022019 Also info on a previous trial using the same product http://www.ncbi.nlm.nih.gov/pubmed/21859051