Recent content by addot

  1. addot

    Repeated Modified Nerve Blocks and Auditory and Non-Auditory Nerve Stimulation

    Yes. The placebo effect can be so strong that people who got placebo surgeries think they were cured. It's why it's so dangerous; people don't just respond to it a little, they can respond to it spectacularly. Like you, there's a part to me that thinks that, hey, if it works, it works. I'll...
  2. addot

    Exploring the Middle Ear Function in Patients with a Cluster of Symptoms

    Same, I reached out to him in June and haven't heard back.
  3. addot

    Hyperacusis Cured/Reduced by Clomipramine

    Did your tinnitus go down to your baseline after stopping, or has it permanently increased?
  4. addot

    Link Between High Psychological Tension, Tensor Tympani Muscle, Hyperacusis and Tinnitus

    Most welcome! I hope you find it enlightening. I'm sorry to hear that. I have often times found it difficult to process that I have caused and worsened my own hyperacusis (obviously non intentionally), but I have also thought that having this happen to you with no discernible cause might feel...
  5. addot

    Link Between High Psychological Tension, Tensor Tympani Muscle, Hyperacusis and Tinnitus

    But that's what I mean. It's also literally what the authors say; I'm using their words. I don't think they're using "threshold" in the sense that it's a super accurate, machine-like system that will contract if a sound is 70 dB but won't contract if it's 69.9999 dB. It just means that your...
  6. addot

    Round and Oval Window Reinforcement for the Treatment of Hyperacusis

    It's possible. Although it's also possible that the pain has become centralized and treating the ear may no longer be effective. Who knows! I just wish there was something out there for hyperacusis that wasn't so uncertain. I went down that rabbit hole for a while today, and just ended up more...
  7. addot

    Link Between High Psychological Tension, Tensor Tympani Muscle, Hyperacusis and Tinnitus

    I take it you have probably read this paper? An Integrative Model Accounting for the Symptom Cluster Triggered After an Acoustic Shock I'm assuming you have, since a lot of what you're saying is basically what these researchers say as well. Namely, that prolonged stress and hypervigilance may...
  8. addot

    Round and Oval Window Reinforcement for the Treatment of Hyperacusis

    Beat you to it! I'm doing that right now lmao. Thanks for pointing me towards it though!
  9. addot

    Round and Oval Window Reinforcement for the Treatment of Hyperacusis

    I'm sorry to hear that. Thank you for trying it and letting us know how it went. Thanks for bringing PRP to my attention, I didn't know about it before. I don't think it would do much for the oval and round windows, like you're describing. Silverstein reinforces them, but hyperacusis isn't...
  10. addot

    Xenon Pharmaceuticals' XEN1101 — Kv7 Potassium Channel Modulator

    No drugs that are close to XEN1101's formula.
  11. addot

    Xenon Pharmaceuticals' XEN1101 — Kv7 Potassium Channel Modulator

    As for Thanos' progress, he is right. Well, sort of. He's right that Thanos is still in the discovery phase with the drug. It's also true that, right now, Thanos doesn't have the resources for clinical trials; he said so himself on the Tinnitus Talk Podcast. Note though that this is very common...
  12. addot

    Round and Oval Window Reinforcement for the Treatment of Hyperacusis

    Thanks, man! Let me know what he says, if you contact him, and I'll let you know what they say if I contact them. Hopefully we can both find some manner of relief from this.
  13. addot

    Xenon Pharmaceuticals' XEN1101 — Kv7 Potassium Channel Modulator

    A couple of possibilities: 1) Retigabine binded to both Kv7.2 and 7.3 channels instead of only one of them. 2) (and this is the one I find most likely) There was no control. I'm not saying these people were lying. It's just that the placebo effect is insidious and very deceptive. If it wasn't...
  14. addot

    Hyperacusis Cured/Reduced by Clomipramine

    What's confusing is that there are lots of folks here for whom Amitriptyline worsened their tinnitus. Clomipramine is also thought to cause tinnitus as well. It's a pity that every single thing that might help hyperacusis seems like playing Russian roulette...