Recent content by Jason Ranovik

Thank you for the kind words, but please note that I am not an expert on the FDA approval process, only on the scientific method and publishing in journals. I can guesstimate at dates for results, and I can understand and help interpret those results for everyone else, but I have no idea how...

I'm really glad to hear this, because I've been on a similar trajectory (although a different cause) and I'm happy to hear that there's a chance the improvement continues. First 6 months was hell, now at the 11-month mark it's notably improved (annoying, instead of debilitating), and I'm hoping...

For everyone looking at the Phase I data, I cannot stress this enough: the Phase I trial had far too small of a sample size for it to mean anything reliable. The purpose of a Phase I trial is to: Quickly detect if there are any major or common adverse effects, so the study can be stopped before...

Yeah, I can't think of anything else that may have done it. I guess I'm just very sensitive to those drugs. Is there something in particular that makes you say it probably didn't do actual damage? It's been 8 months, I haven't heard of tinnitus subsiding after that long.

I was on the SSRI for about 7 to 10 days before this started, but the dose was gradually ramping up over that time (although even when it started, I was only at 10mg/day, which is 10-20% of the normal therapeutic dose). I wasn't sick at all that week, as far as I can remember.

Most of yesterday was pretty much the normal 4/10 for me. Last night I went over to a friend's place, had a nice dinner, played some Mario Kart, a couple beers. Came home and chilled for a bit. Got ready for bed and noticed that I wasn't hearing any ringing... odd. Got into bed and spent a half...

I'm a scientist (PhD) who has published a number of research papers, so I can shed some light on the process. Note that I'm not in the medical field though, so the process is surely a bit different. The analytics/statistics that will be run on the data are defined in advance, i.e. they know...

Thanks for the comments! Everyone seems to be focusing on the treatment aspect though, but I'm actually more interested in the evaluation aspect. I'm familiar with the lack of known treatments, but I'm sure there must be a high-end clinic somewhere in the world that specializes in tinnitus...

Just FYI, the recruitment for the Phase II trial is now closed (and has been for a while, seems like), which means they're evaluating their last round of participants. Data on the 400-participant trial should be out in the next 3 - 6 months, which will be far more useful for evaluation than the...

I did, first dose on April 8, 2021. The tinnitus started on May 21, so 6 weeks later. I thought about the connection, but seemed like too far apart for it to be related.

Hi everyone, Been a lurker for a while, finally decided to sign up and introduce myself, maybe get some feedback. Specifically, thoughts on what a possible cause could be, what evaluations I might ask for, and what treatments I might try. Onset: May 2021 (8 months ago) I fell asleep on the...

Hi everyone, I've been an observer for a while, watching the threads on new treatments and such. My T started about 8 months ago from an unknown cause; one night I fell asleep on the couch, and when I woke up an hour or two later I had a weird ringing in my left year. It might be related to an...