Recent content by lapidus

Webinar from October this year:

I'm curious about BHV-2100, their drug for chronic pain disorders and if that would have any effect on noxacusis. It's still only in preclinical though.

@Nick47, I know you ran out of Gabapentin but did you manage to get a new prescription? You're writing about it as if you're currently on it so I figure you did? You mentioned in another thread that it reduced the reactivity of your tinnitus. Do you mean that it reduced the reactivity...

Fairly recent study on red and infrared laser therapy for tinnitus. It was published in March this year. → Effects of Red and Infrared Laser Therapy in Patients with Tinnitus: A Double-Blind, Clinical, Randomized Controlled Study Combining Light with Ultrasound, Drugs and Vacuum Therapy

I find it a bit odd that they are excluding somatic tinnitus since approximately 60-80% of all tinnitus sufferers have somatic components despite not having a somatic cause.

It was a couple of years ago I tried the Bose ones out but IIRC, Bose was the leading brand back then when it came to noise cancellation. I don't know about specific models but I'm sure there are lots of reviews and rank lists out there for noise-cancelling headphones that are currently on the...

Noise-cancelling headphones are generally quite good at blocking out low-frequency noise such as road noise, engines etc, but less good at high frequencies. I've tried Bose noise-cancelling headphones for car rides and they were good at blocking out low frequencies but the noise-cancelling...

Do you (or anyone else) remember if there was such a discrepancy between treatment Group 1 and Group 2 in the Phase 1 study? Though that was a study with only 20 patients so it might be harder to find such trends and patterns in there?

Then there's also the Kv3.1 which I guess some research must've shown that it's also expressed in the inner ear since Autifony's drug AUT00063, specifically for tinnitus, acted on the Kv3.1. But that turned out to be a dud and they cancelled the drug halfway through Phase 2 due to no effect. I...

But this was Phase 1. In Phase 2 the tinnitus continued to improve even after the treatment period, according to Shore's presentation from December.

When I read it fast at first I interpreted it as not having had tinnitus for more than 12 years. Looking at it again, I interpret it as there is no limit on how long you've had tinnitus as long as it hasn't been bothersome for more than 12 years. For example, you could've had it for 30...

A bit curious about this Polish study. Since it isn't invasive (you just put a thingy into the ear canal, just like you'd do with an earplug) and the results were quite impressive, wouldn't this be pretty easy to get to market?

Pimozide is not on the market here in Sweden. The last form of it (Orap 2 mg) was taken off the market in 2001. I can't find any information on why it was taken from the Swedish market though.

Why didn't they include a fourth arm with 0.3 mg in this trial?

Sound Pharmaceuticals. Here's the thread: Sound Pharmaceuticals (SPI-5557 & SPI-1005)