Recent content by lolkas

  1. lolkas

    New University of Michigan Tinnitus Discovery — Signal Timing

    Yes, the technology at the time was definitely not advanced enough. Today, we live in a much more advanced world. In my opinion, a lot of progress in the field of hearing is still lacking, particularly in imaging technology. Better imaging would allow us to clearly see what’s missing and...
  2. lolkas

    Cilcare's CIL001 Targets Cochlear Synaptopathy — An American/French Collaboration

    I have been following regenerative approaches since 2016 and have observed many developments. The same applies to Dr. Susan Shore and other approaches specifically for tinnitus management. Past hearing regeneration efforts discussed on Tinnitus Talk, like Frequency Therapeutics and others...
  3. lolkas

    New University of Michigan Tinnitus Discovery — Signal Timing

    In my view, if a billionaire (or a few) were to develop tinnitus, it would not just be about the financial aspect. It would also involve the business side of things as they know how to get things organized and done quickly. Sometimes I cannot help but wonder: what if that actually happened? How...
  4. lolkas

    New University of Michigan Tinnitus Discovery — Signal Timing

    I agree with many of your points and have some speculative thoughts of my own: Could it be that they want to release the device in a way that prevents counterfeiting? It is almost 2025, and creating devices with encrypted storage is not a challenge anymore, even on a large scale. This would...
  5. lolkas

    Poll: Would You Trade Your Tinnitus for a 5-Year Prison Sentence?

    This question may sound silly, but it brings up an interesting idea. What if there were a combination of questions one could answer that would demonstrate to the world how impactful this condition is? I think the Tinnitus Quest team would also like to see such a “live” questionnaire being...
  6. lolkas

    Introducing Tinnitus Quest

    Tinnitus Quest is a great initiative. Currently, there is practically ZERO representation of the hearing loss/tinnitus population (ATA is a joke, in my view), and if Tinnitus Quest could reach out to the world, that would be fantastic! I think there is also a lack of communication between...
  7. lolkas

    Rinri Therapeutics

    I don’t think that their procedure is more complicated than a cochlear implant surgery, which is pretty much outpatient. They want to be able to accurately deliver the drug via the round window, therefore I think they will cut behind the ear and to it like that, or perhaps they will make a...
  8. lolkas

    Reformulated Retigabine (Trobalt): BHV-7000, a Kv7.2 Modulator by Biohaven (Pfizer)

    How common would it be for someone to have damaged potassium channels? I would imagine that is something like stroke or genetic mutations? I mean if someone would have their potassium channels damaged, then Trobalt would not work for epilepsy either. I don’t think that an acoustic trauma can...
  9. lolkas

    Evidence of Cochlear Neural Degeneration in Normal-Hearing Subjects with Tinnitus

    Okay, so here is my problem with it: what does “nerve loss” mean? Like you have totally fine outer hair cell & inner hair cell situation in cochlea, and all of a sudden the nerve bundle between the cochlea and the brain gets damaged? Is this what they mean? I find this extremely unlikely to be a...
  10. lolkas

    Xenon Pharmaceuticals' XEN1101 — Kv7 Potassium Channel Modulator

    Can you or @ErikaS share a link for the trial's contact information, please? I cannot find it on the web. Ty!
  11. lolkas

    Xenon Pharmaceuticals' XEN1101 — Kv7 Potassium Channel Modulator

    I live in NYC. Could I try to enroll in the trial?
  12. lolkas

    New University of Michigan Tinnitus Discovery — Signal Timing

    The device needs to be used constantly, until something can regenerate the hearing damage somehow. I see what you are saying though.
  13. lolkas

    Reformulated Retigabine (Trobalt): BHV-7000, a Kv7.2 Modulator by Biohaven (Pfizer)

    If I am reading it right, the majority saw improvements, very little worsening overall and we don’t really know what these worsening are from anyways (could be something else). Trying to correlate epilepsy with tinnitus, and if the drug takes about equal time to work on both epilepsy and...
  14. lolkas

    Reformulated Retigabine (Trobalt): BHV-7000, a Kv7.2 Modulator by Biohaven (Pfizer)

    This definitely sucks but I was sure of them denying the request (unfortunately). They are definitely not planning on trialing this on anything BUT what they know this will work on. Even if they have people with tinnitus in the trial being treated for epilepsy and they report positive effect on...
  15. lolkas

    Xenon Pharmaceuticals' XEN1101 — Kv7 Potassium Channel Modulator

    It would be nice to also know how much of a reduction (subjective of course) he got? I read that people's tinnitus got eliminated while on Trobalt.