Recent content by Pete88

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    Xenon Pharmaceuticals' XEN1101 — Kv7 Potassium Channel Modulator

    Because it is based off another drug that was apparently quite effective for tinnitus but unfortunately had too many side effects and had to be pulled. The idea is that they have tweaked it enough to ditch the side effects but remain effective against tinnitus. I think...
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    Xenon Pharmaceuticals' XEN1101 — Kv7 Potassium Channel Modulator

    Didn't Trobalt pass a safety test, only to reveal major side affects later on?
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    Frequency Therapeutics — Hearing Loss Regeneration

    Has anyone heard how this thing went?
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    Frequency Therapeutics — Hearing Loss Regeneration

    Yeah you're absolutely right. It's just that if you had the type of blood cancer the new drug didn't help, it would be personally disappointing. However, if you were just an impartial observer, any progress is incredible. Everyone was hoping FX-322 would fix all the hair cells it touched and...
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    Frequency Therapeutics — Hearing Loss Regeneration

    I agree. There was a lot of emotion riding on good results. All I'm saying is that people need to recognize when emotion is in the driver's seat.
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    Frequency Therapeutics — Hearing Loss Regeneration

    Yeah, possibly! Again, remember when he showed up and so many people jumped down his throat and aggressively mocked him?
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    Frequency Therapeutics — Hearing Loss Regeneration

    Wow, I feel dumb. You are right. I read it as "previously undisclosed". This got less exciting. Now it sounds like they're just trying to salvage the lackluster results of one of those old studies.
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    Frequency Therapeutics — Hearing Loss Regeneration

    Without investing too much emotion, this seems like a good sign. Basically a secret trial that if it had bad results, would be swept under rug. I know people will point out the possible sketchiness of the scenario but this is promising!
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    Otonomy OTO-313 — Treatment of Tinnitus

    "The greater good" is exactly why they did it. That is why they are known as the "greatest generation". They knew the risks but also knew what had to be accomplished. You couldn't get most 18-24-year-olds today to delete their TikTok accounts. Anyway, let's not derail this thread lol.
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    Otonomy OTO-313 — Treatment of Tinnitus

    Imagine if the soldiers on D-Day were like "I'm not storming the beach on the first day! I'm not one of those suckers who are possibly gonna get shot! I'm just gonna wait until it gets all cleared".
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    Frequency Therapeutics — Hearing Loss Regeneration

    I can't be bothered to bring up the exact numbers and percentages but I remember that if you really looked at the numbers, there was only a small percentage of people that had the room to get better by an amount that could be classified as statistically meaningful. So it actually was a decent...
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    Frequency Therapeutics — Hearing Loss Regeneration

    Agreed. At least prior to the Phase 2a results, all the available evidence looked very favorable. Coming out against it was more based in pessimism. Now they have single dose studies that can't live up to the assumptions set by the safety study.
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    Frequency Therapeutics — Hearing Loss Regeneration

    I am on the side that thinks restoring input to the brain can lessen/stop tinnitus, at least sometimes. However, I do appreciate your scrutiny as I agree with the "echo-chamberish" comments. I've seen people in the thread repeat blatantly false information that sounds promising and these same...
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    Machine Learning, Predictions, Psychological Multimodal Therapies

    Ahh ok, cool. Thank you very much for the explanation!
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    Machine Learning, Predictions, Psychological Multimodal Therapies

    Sorry, so what's the take away from this? Thanks!