Recent content by PhilB

That's a very important point about T and I would guess that it applies to many of us. I am also realising that it is not the volume or pitch of my T which fluctuates from day to day. The thing that varies is my ability to deal with it. Some days it feels like the end of the world - other days...

I used to do the exact same thing. There was a time when I would lie in bed listening to generalfuzz ACRN tones on an mp3 player to quieten the T before going to sleep. Since then, I have habituated to the point where T no longer prevents me from sleeping. It still bothers me sometimes during...

@smel - I have played around with ACRN (courtesy of generalfuzz) in the past and experienced temporary benefits very similar to what you describe - reduction or elimination of the main T tone so that all you have left is a much more tolerable hiss. Much like yourself, I found that an hour of...

I agree with @bill 112, you might think that T has impaired your cognitive ability but your T is only weeks old. There is still time for it to improve or disappear althogether. It's true that not everyone's T gets significantly better over time. I can't say mine has altered much in the last 2...

@Telis - I think you are correct that severe T of the type which can be heard above almost any level of external sound is a different phenomenon to minor T and present a different magnitude of problem to those who suffer from it. But I think you are wrong to criticise other people who offer...

People with T are often told that they just need to wait for habituation to occur but habituation never happens to those who are consciously waiting to habituate. My analogy is that it is like waiting for a bus which is very late. Eventually, you might give up waiting for the bus and begin to...

The interim analysis carried out by the Independent Data Monitoring Committee looked at trial data on 58 subjects. I don't think we know whether that means that only 58 subjects completed the trial. It is possible that these were just the first 58 to complete. Of those 58, I don't think we know...

My cat often pricks up its ears when I use the TV remote. Not being technical, I had assumed that the remote control technology made use of high-pitch sound frequencies which were imperceptible to the human ear but audible to cats. Having just googled remote control technology, I now realise...

The findings will be published in due course, therefore any speculation is essentially futile but I can't help wondering if the failure to obtain positive results may be at least partly due to false positives in the control group. For example (and this is just hypothetical), let us suppose that...

@valeri - who knows? All we know at the moment is that the CLARITY study into AUT00063 as treatment for age-related hearing loss is still going ahead as planned.

For anyone who wishes to know more about the role of Data Monitoring Committees in clinical trials, this document may be of interest: http://www.hra.nhs.uk/documents/2013/10/data-monitoring-committees-in-clinical-trials.pdf "A Data Monitoring Committee (DMC) is a group of people that reviews...

Is it standard practice for a Phase 2 clinical trial to be abandoned mid-way through due to initial findings showing no indication of success? I don't know the answer to this question, maybe someone else will know. I would have thought that once a clinical trial has started, it will normally...

You're right that the study seems to be taking a long time due to a shortage of eligible participants but I don't think the size of the UK population is the problem here. The UK is the 22nd most populous nation on earth with 64.8 million people according to recent estimates. There should be...

I think the info in the email from Autifony quoted by @Dubbyaman (and earlier by @111) should be treated as reliable and is the most authoritative source of information we have on the likely timescale for availability of AUT00063. That email says "3+ years after finishing this study" (by which...

Your information is slightly outdated, @Danny Boy - An NHS prescription currently costs £8.20. http://www.nhs.uk/NHSEngland/Healthcosts/Pages/Prescriptioncosts.aspx In any case, I do not think many non-epileptic T-sufferers have been successful in persuading their GPs to prescribe Trobalt for...