Recent content by Pre55ure

  1. Pre55ure

    Do Any of You Live by Yourself with Hyperacusis?

    I have a pair of the Peltor earmuffs as well, they are my preferred "everyday" protection, though they don't offer as much noise reduction as the foam earplugs.
  2. Pre55ure

    Otonomy OTO-413 — Treatment of Hidden Hearing Loss

    I have wondered about the experience of having the IT injected gel and if that might qualify as an "adverse effect" for some people. I have had multiple IT injections over the past year and they are never fun, but they also aren't that bad. However, I have always gotten prednisone or...
  3. Pre55ure

    Otonomy OTO-413 — Treatment of Hidden Hearing Loss

    My understanding is that Otonomy believes that their delivery method is superior to something like FX-322. Is there any information released anywhere on how deep into the cochlea they believe that their drugs can be effective? Basically, do we know if there is a lower frequency threshold at...
  4. Pre55ure

    Frequency Therapeutics — Hearing Loss Regeneration

    Seems very unlikely. The part of your cochlea that FX-322 will help is is different and distinct from the part that regulates balance.
  5. Pre55ure

    Frequency Therapeutics — Hearing Loss Regeneration

    I can't really answer your other questions, but I have researched this one so I'll take a stab at answering it. This would obviously rely on what the individual's extended audiograms looked like before being treated with FX-322. If the hearing loss was the result of age - then I believe that...
  6. Pre55ure

    Otonomy OTO-413 — Treatment of Hidden Hearing Loss

    Thanks for the explanation. That was a very clear and concise way to put it. That isn't the part that I found hard to follow though. (I actually work designing audio equipment so dB's and logarithmic scales aren't the part I was having trouble with). Rereading the post, I think it's just more an...
  7. Pre55ure

    Migraines and Chronic Ear/Vestibular Troubles

    Sorry to necrobump an old thread but wondering if there is anyone here who is still in the same boat? Been suffering with cochlear migraines (similar to vestibular migraines but mainly affecting hearing rather than balance) for about a year now, and would like to hear of any other people's...
  8. Pre55ure

    Otonomy OTO-413 — Treatment of Hidden Hearing Loss

    Can you clarify this part? I'd like to understand what you are saying here but I'm confused by how this is worded.
  9. Pre55ure

    Frequency Therapeutics — Hearing Loss Regeneration

    When my ears worked I didn't have tinnitus. Now that they don't - I do. There's lots of examples of improvements to hearing helping to reduce tinnitus, no reason to think this would be different.
  10. Pre55ure

    Frequency Therapeutics — Hearing Loss Regeneration

    I really think any one who is overly worried about the IT injection part of this is blowing it way out of proportion. It does look and seems kind of scary, (I've had it done 6 times now by 3 different doctors) but it is very much just like Jack V describes - a bit of numbing gel on the eardrum...
  11. Pre55ure

    Aldosterone and Hearing

    I'm all for trying anything that might help (assuming it doesn't have more than minor adverse effects) but the underlying causes of high frequency (age related) hearing loss and low frequency hearing loss are so different and distinct, do you really think this has much hope of helping? Either...
  12. Pre55ure

    Sound Pharmaceuticals (SPI-5557 & SPI-1005)

    The results of the trials showed good results in reducing tinnitus and increased low frequency hearing response in patients with Meniere's Disease. It's not aiming to have the same type of effect that something like FX-322 is, but there are more conditions than just Meniere's that it can...
  13. Pre55ure

    Sound Pharmaceuticals (SPI-5557 & SPI-1005)

    Thank you both for posting that / informing me of that study.
  14. Pre55ure

    Otonomy OTO-313 — Treatment of Tinnitus

    I certainly think that for the majority of people, restoring hearing will hopefully cure or at least greatly reduce their tinnitus issues/suffering. However, I think it is a bit short sighted to think of these other avenues of treatment as a "dead end", there are a large number of people whose...
  15. Pre55ure

    Sound Pharmaceuticals (SPI-5557 & SPI-1005)

    Thanks for that info, I'm very interested in SPI-1005. I haven't been diagnosed with Meniere's - but I share a lot of the same symptoms (episodic intense tinnitus, fluctuating hearing loss). The potential connection to viral inflammation is really interesting. Do you have a link where I could...