HomeoHebbian
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  • Is it beneficial to take Magnesium threonate for people with hyperacusis and tinnitus, @HomeoHebbian?
    HomeoHebbian
    I'm sorry that I can't be of any help with this question.
    Heal82
    I take one capsule of this every night before sleeping and it helps me a lot.
    Eleva Nutrition Apigenin Theanine Magnesium Bisglycinate 3-in-1 Complex Supplement Support Relaxation - Made in The USA - Zero Fillers - Gluten Free & Non-GMO - 120 Veggie Capsules https://a.co/d/5n9p3ZD
    Thank you for participating in this forum. We really need someone from the scientific community here, even if you participate anonymously.
    Hi, what are your views on the potential of NMDA receptor antagonist gacyclidine in the treatment of tinnitus? I see Otonomy are evaluating this drug in a phase 2, do you think that this may even treat chronic as well as acute tinnitus?
    HomeoHebbian
    This is the only study I could find - Eur Arch Otorhinolaryngol. 2010 May;267(5):691-9. doi: 10.1007/s00405-009-1126-1. Epub 2009 Oct 22.
    Effects of extracochlear gacyclidine perfusion on tinnitus in humans: a case series.

    Wenzel GI1, Warnecke A, Stöver T, Lenarz T.
    HomeoHebbian
    1) no control, 2) effects were temporary, 3) doesn't really make sense.
    HomeoHebbian
    Otonomy is a hammer looking for a nail. They have a bunch of patents on this method for cochlear drug delivery and now they are fishing for possibles uses.
    Do you believe treatments such as deep brain stimulation or rTMS, offer any prospect of success?
    P
    It seems clear we are a long way off to defining protocols to use these methods rTMS and DBS effectively.
    HomeoHebbian
    It is like trying to solve the puzzle on Wheel of Fortune with only one or two letters revealed. The parameter space for how/where/when to stimulate using rTMS and DBS is vast and we have very few guiding principles in place for the appropriate use of these technologies for tinnitus, specifically.
    HomeoHebbian
    As a field, we need to test interventions and not just fiddle around, but we also need good objective markers of the pathophysiology underlying tinnitus. At present, we don't know what it is we are trying to erase, reverse, correct etc. so, unfortunately, these efforts are shots in the dark for the time being.
    Director of a tinnitus research laboratory
    Hi Professor. I'm a new member and had a question on your research. Is this a private way to message?
    Neuroscience Professor obsessed with understanding and eradicating tinnitus
    HomeoHebbian
    Sure, you can message me directly through the "Conversations" tab on this website. It is private.
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