Not the cold and winter, the isolation probably, but what I do know is that at the end of February, when it starts to loosen up and go to springtime my T will go absolutely dreadfully bananas and I will have a horrible time for a month. Happens EVERY SINGLE YEAR. I'm not amused.
Winters are so different than in past, with more abnormal fluctuations w/ barometric pressure, the up/down temperatures, which does feel to disrupt, affect my fragile ears/brain symptoms.