Search results for query: *

All of us want our baby ultrasonic hearing back :)

Cure is defined by success of the treatment Relief from symptoms to an adequate degree or full recovery is what everyone seeks and that would be cure “more or less”

Both Progenitor cells exist in both layers

This happens in every intratympanic injection procedure, there is a temporary “damage” to the tympanic membrane which causes our constant and beloved tinnitus which fades away, they just have to mention it

I cant stand this acoustic assymetry anymore, looking forward for this to come out and work like a charm

If their first attempt fails, their entire approach fails, PCA fails so i assume they are not just betting on multiple horses!

I have mentioned inner ear regeneration to six of them and nobody knew nothing, imagine i was quite careful not to be heard as a fool I would also stick to financial advice, they seem to be doing good without doing anything (at least for the majority of us in here with tinnitus and hearing loss )

That's for your first question, as far as retreatment options i was thinking the same some days before, it would also make a meaningful business model for the company, charging per treatment, some may need one some may need multiple

Enjoy

Its nothing like scar healing, its an apoptotic mechanism, imagine like a skin cell apoptosis but without the regeneration

FT speaks the words “body healing” everytime they mention their therapy procedure, thus administer a drug and then the inactive healing mechanism becomes active and the body itself manages the regeneration! Nobody knows for sure till they let us know what they have figured out already, cause...

I am asking only because it's normal to have a slight increase for a few days (even weeks) due to the nature of the procedure (conductive loss due to the membrane perforation). If that was the case then probably we are talking about zero gains.

@ryant, do you think that these increases could be connected with the healing time your tympanic membrane needs after each injection?

The fast track route seems to be working with various gene treatment candidates, otherwise we are gonna be around here for quite some time :) And to be honest, my main concern and strugle is hearing loss so i am waiting like a fool such a treatment! Tinnitus? I had my time to adapt, it was quite...

Totally out of topic but it is not necessary to go public, VCs make money through original investment via ownership, this means that even if the company is not acquired in the future (for big money, thus big profit for them) they still make money from dividends (still i think that there are more...

Dunno if its posted somewhere but it is a nice read for the ones in the medical field (even though a lot of folks in here have gained such knowledge through their difficult times researching) https://helda.helsinki.fi/bitstream/handle/10138/205633/postmito.pdf?sequence=1

Actually everybody does :) Hopefully ft will realease their paper sometime before the end of the year

Any papers on that?

No surprise at all, even this date seems a bit optimistic :) i was hoping that they just dont update the trial data that often but that was not the case! If we take into account FTs approach, even administering the drug to a profoundly deaf persons cochlea would be beneficial, CI receivers are...

Actually it is "This is a phase 1 safety study" But unfortunately no news yet

Wow

Well thats all about it, you pretty much figured this out already You should give HBO a try if you can, i didnt, but i am not sure i regret it, my doctor who happens to be a military ENT told me that probably i wouldnt see any difference BUT you do HBO for hearing loss, not for Tinnitus, i dont...

Even though i dont want to be off topic Ill post sometime soon my story but briefly, it took me 5 months, much better now in my 6th, it is reduced, but who am i kidding? It has its ups and downs but i definately dont react the same to my T, i am much more “who gives a crap” when i used to be all...

You said it, I did wonder when did you get your tinnitus and I saw that we are two days apart, keep on, it only gets better!

I would happily pay $20000 (given it works and restores 100% of my hearing plus they give me an extra injection for the healthy one so that i can hear like a baby once again) (You know that we will compensate for the ones who wont even bother for such a therapy so that the companies still get...

I like stories... when its bed time (In my story, when i get it written someday here there is something that can relate to what you just said)

I only know that i was perfectly fine... till a mortar blast, ear fullness, hearing loss and 6 days after tinnitus started... yes it alters with movements of my neck but please... hearing loss the golden standard for tinnitus

Seems on schedule

https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=372587

There are many articles online, but still nothing yet available

Gene therapies will work for you :)

https://jamanetwork.com/journals/jama/fullarticle/2643629?amp;utm_source=JAMAPublishAheadofPrint&utm_campaign=07-07-2017 Good ending

When do we expect the next one?

But still you sound a bit pessimistic I would suggest you dig a little further in Fx, as a neuroscientist it would be really interesting...i bet

It may be a better alternative to intratympanic cortisone injections after Acute Acoustic Traumas

Not quite practical to go through intratympanic injection whenever you feel like you have a major spike

Great news!

http://hearinghealthmatters.org/hearingnewswatch/2017/auris-medical-am-111-drug-to-treat-sudden-sensorineural-hearing-loss-0705/

Participants must be adult and audiometric threshold of 80 decibel [dB] hearing loss [HL] or poorer at 500 Hertz [Hz] This is way beyond moderate hearing loss and participants are already scheduled for CI placement

Its a pity that they are going through cochlear placement surgery but if the goal is to measure the drug concentration in the cochlea i guess its the only way to do it, still even in this case i would like to know if it has any effect and i still hope that the patients are gonna gain something...

Off course because it is quite invasive uppon placing

Hoping is the only thing i can do Its been three terrible months of my brain overloading all day long and i just wish i could wake up one day without T and have my solid stereo hearing back Wish that for everybody

Still hoping for some kind of imaging diagnostics in a cellular level so that all if these questions can be answered By the time frequencys approach wont use up all the supporting cells for regeneration but will replicate them maybe multiple treatments is some kind of possible solution?

http://www.businesswire.com/news/home/20170619005396/en/Frequency-Therapeutics-Presented-Data-International-Society-Stem

https://en.m.wikipedia.org/wiki/Base_pair Scroll down "length measurements"

https://www.firstwordpharma.com/node/1480913

Hopefully things are gonna speed up, even 5 years seems too long i think

They mean clinical trials

http://www.genengnews.com/gen-articles/targeting-progenitor-cells-to-regenerate-damaged-tissue/6084

As a dentist i always recommend ear protection, i came into this community early in my life and my work only to find out that dentists are exposed in sounds that in the long term cause heavy damage in their ears, we are just very tolerant in the beggning and senseless in the years to come... its...

Good thing is that there are companies not regulated by FDA outside of US and EU, i just think that maybe things are speeding up more under these circumstances

Whatever the case is i would prefer complete restoration of my hearing ability, if be company does that then there is no reason for others to exist

Nope

I would like to know why it seems so that they have figured it out, there are still so many questions waiting to be answered from people that are nowhere near the medical field but yet they seem to bring up the difficulties of such treatments all the time in such threads

Thats also my case, high dbs and i notice, lower and not so much

The distortions i guess are what we call recruitment right? I have it also much less now after two months from my acoustic trauma but i hope its gonna get better

I think it is, unfortunately its not suitable for the majority of us inside here but it will be for sure a step forward, i just wish they will focus more on regeneration therapies Ps. It just happens that i did get my acoustic trauma during my military service and during that time i had to deal...

Prevention is what i understand as far as it has to do with the trials

Yes, BUT they mention the preventive therapy not the regeneration therapy

Why not super high frequencies? I suppose if they are capable of curing the lower ones the super high ones are easier cause they are more accessible (basal region)