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That's it I'm fed up with hyperacusis. Tomorrow I'll ask my psychiatrist to put me on Clomipramine.

They're going to trial our patience ;)

That’s awesome! So they have started already? I am hopeful for Rinri, and that this trial will have good results! Then we will know for sure!

It's the loudness chart from the 6-week pivotal crossover trial. That's one stumbling block with the 6-week crossover trial. Another one is that the control group also exhibited a placebo effect in Treatment 1. To the best of my knowledge, UMich hasn't publicly addressed that fact yet. Just on...

Hi @Nick47, thanks for your response. I am not OP, but a lot of your advice that I've read has been helpful to me. I've also had tinnitus since a young age, 14, with it only getting far worse in the last 3 months. I've been meaning to write my Introduction soon. I do hope you reply there as...

Check my post. I found that ear steroids helped. Then on-ear headphones and silicone over-ear.

There goes another ISSNHL attack. I’m losing my hearing bit by bit. :(

@Yu.3, I believe the overall volume has gotten subjectively quieter. A large part is due to my no longer experiencing spikes, which came naturally with habituation. There are definitely some days when my tinnitus is louder than usual, too, but at this point, it no longer has an emotional effect...

I missed that. What did they say about another trial?

Hey, thanks so much for taking the time to reply. I appreciate it. Please tell me how TRT goes! I'm really hoping yours continues to get quieter and magically vanishes lol. I hate the situation we're in, but gotta have faith and remain positive (easier said than done).

Interesting that the tinnitus resolved: "After 2 months, the patient reported a slight subjective improvement in his hearing, and the tinnitus had resolved."

Thanks for the response. I went to the ENT and everything looked OK. I was told to come back if it is still the same or worse in a week or more. It has been no fun for sure, although it did teach me to respect my hearing a bit more.

Trump's own mortgages reveal the scandal he accused others of doing. In 1993 Trump signed a mortgage for a Palm Beach property and certified that it would be his principal residence. Just seven weeks later, he signed another mortgage for the neighboring home and made the same pledge. Records...

Hello everyone. I am a woman in my 40s who’s dealt with tinnitus for close to 30 years. I’ve had regular tinnitus and occasionally pulsatile tinnitus. I had many ear infections as a child, although I never had tubes. Even as an adult, I’d get ear infections easily (inner and outer), and I...

Another consideration is that some people with ADHD and/or severe anxiety are in constant fight-or-flight mode, where the brain believes tinnitus is a threat/danger. This means the auditory cortex increases its sensitivity, and thus tinnitus is more persistent and intrusive. @ndhtdb, I don't...

Me too, @DebInAustralia.

I agree with @Nick47 and @MindOverMatter. It really depends on what you’ve got and your own tolerances and risk aversions. For example, I had what turned out to be medication-induced tinnitus about 12 years ago in my 20s, along with a brief episode of what I now know to be dyacusis that the...

It would be helpful if they provided more detail

Does anyone have contact with @another_person? I hope they've managed to get some temporary support at least.

Sigh. Another ear problem. My hearing dropped again, but when I plug both ears, my voice sounds the same in both. What is this?

I'm really sorry to hear about your experience but please do not throw money at "miracle cures". If 2 x steroid injections have not cured your SSNHL then I'm afraid you might just have to accept that the hearing loss might be permanent. Tinnitus does not have to be permanent. You may not be...

I really hate how those hearing drop out/tinnitus episodes we've all likely experienced throughout life now last so much longer... Always spikes my anxiety when it lasts longer than 30 seconds that this time it's not going to end. Plus they always make my ear feel crap afterwards now.

I think she's mentioned having them elsewhere on the forum. I believe there are some available medications to address the pain they cause, certainly something worth consulting with the doctor about, along with the ideations. With that Dr. Djalilian article you posted the other week, I wonder if...

Sorry to hear you’ve joined the journey. 60dB is absolutely fine. I’m fairly sure that above 70dB is the point where any damage can occur, and at those low levels, it’s not going to be catastrophic anyway. Still, your ears are going to be a bit sensitive at the moment. Setbacks are common in...

Do you really believe it takes 7-8 years to consolidate the device? In the presentation, they included a further trial requirement.

There really needs to be a more prominent warning on that stuff. They know that it absolutely will melt a cochlea when put in the middle ear, but they keep dishing it out to people freely because, for most people, damage is invisible if it isn't pushing them over the line to where they will...

Noise-induced tinnitus can definitely improve with time. Plenty of cases on here of people improving, even a few years down the track. Keep the faith, my friend.

Ear injections are generally a better choice. They have no systemic side effects, a low risk profile, and the injections aren’t harmful to the ear, so there’s no risk of increasing the tinnitus. It’s worth a shot if you have a provider who has empathy. I’ve taken high-dose oral Prednisone for...

I hate to say this, but both medications spiked my tinnitus. They were taken at separate times. I took Mirtazapine for 8 days. Initially it helped with sleep a lot, but after about 5 days I started having brain zaps, so I stopped it. I reset to baseline after about 2 weeks. Betahistine spiked...

I’ve taken CoQ10 for 3 months before and I swear it worsened my tinnitus. I also took a supplement called SoundBytes that made my tinnitus worse. I’ve never had any supplements do a thing for me. Let me know if you find anything that’s really effective.

Sounds like there may be cervical issues or loss of cervical lordosis. With the somatic features you described and this strange “bouncy” sensation, I have to wonder what your cervical spine condition is. A lot of young people have tech neck and poor posture. What about a simple neck X-ray to...

I’m a 25-year-old male with tinnitus that also started in late October this year. I don’t know what I can really say besides that I feel you. We have a whole life ahead of us, yet unfortunately we get hit so early. My tinnitus has reduced a bit since the onset, but it’s still very noticeable in...

Good evening. I’m a 52-year-old male. I recently had a bad sinus infection, and my upper back teeth started hurting, which I believed was caused by nicotine pouches. I was prescribed Doxycycline. I’ve taken Doxycycline a few times before with no issue. On my last day of Doxycycline, I went to...

@Lukee, I know this is an old post, and I hope it finds you well! I'm dealing with ETD and glue ear that will not go away. For 3 weeks, I've been using Flonase and taking Mucinex, NAC, and glycine. NAC and glycine are necessary for glutathione, but I was wondering if the glutathione nasal...

Q. If Dr. Djalilian theorizes that reactive and fluctuating tinnitus is linked to atypical migraines, and elevated CGRP with subsequent trigeminal nerve inflammation is the cause, I’d be curious why he doesn’t recommend a trial of pharmaceutical CGRP inhibitors such as Ajovy.

The weekend's interviews highlighted a growing pattern of ICE detaining U.S. citizens. When confronted with video of a young mother chased to her home and detained despite repeatedly stating she was a citizen, "border czar" Tom Homan excused the conduct by claiming that many undocumented...

I've been producing music everyday for nearly a whole month now, just on my laptop speakers, mostly quiet. i used to produce a lot of music before in headphones (and never got T from that). Anyway, it's the only thing that makes me not wanna die and I don't hear the T during it, I helps me...

No, they said that the delay was primarily because the proof-of-concept device they used in the study was too complex. It involved software running on a computer and a few other computers, which meant that the computer and all its components needed to be approved by the FDA as "medical grade"...

@Nick47, and others, including myself, often give advice in accordance with our own personal experiences. Nobody said "one size fits all". In the end, what people want and are willing to do is entirely up to themselves. Everyone has to take responsibility for their own lives. Learn by living...

Thanks for the update, @Paulie87. Clonazepam has been very effective for me when needed. Does your psychiatrist have a long-term view of you using it, or planning to taper you off it? Nick

I am prescribed 2 mg Klonopin daily. I take 1 mg in the morning and 1 mg at night, around 2 hours before bed, for days when my tinnitus is really bad. Klonopin does work to reduce tinnitus, there is no arguing that. It takes mine from about a 7 out of 10 down to about a 2 out of 10. It is very...

Coenzyme Q10 and its Therapeutic Effect on Tinnitus

It's interesting how easily others seem to get their hands on benzos. I was only offered in the very first days, and then, it was only a 10 count of Valium and told that would be it. I won't ask for it for fear of being marked as drug-seeking in my patient record.

I'd absolutely love to be this drugged up and have no issues lol. Sadly, I foresee it causing more issues than it solves for myself. Surprised your friend is doing so well on all that, although I imagine if he ever stops, it might be difficult...

As in nanoparticles that are able to deliver drugs to specific areas of the inner ear?

I don't agree with @Nick47 entirely either, but I believe his advice comes from a place of care. Not all our tinnitus is the same. I personally notice a vast difference between my local cinema & concerts, for example, but everyone is different. My very severe reactive tinnitus has settled...

@LovableGamer, to be honest, I'm only optimistic about Rinri.

Is this chart from the initial 4-week trial? As I recall, and it's been a while since I've read the papers, the 4-week trial did not show lasting improvement, but the 6-week trial did. The stumbling block was that in the 6-week trial, the control placebo group did not show improvement when they...

This sounds pretty cool! So we might see trials for hearing loss with this nanotechnology? It should restore hearing? That is what I gather from reading this.