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  1. U

    Frequency Therapeutics — Hearing Loss Regeneration

    Yes. Done after suffering profound ISSHL to rule out round window membrane rupture. So the question arises if this reinforcement might have a negative impact and thus needs to be undone first (if even possible) or requires some special form of direct inner ear delivery of FX-322 (like this) or...
  2. U

    Frequency Therapeutics — Hearing Loss Regeneration

    Are there any experiences or concepts of FX-322 or OTO-413 passing or bypassing a surgically sealed round window membrane (connective tissue added during tympanotomy) to enter the cochlea in a somehow promising concentration? Anyway, would love to experiment one day to find out.