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  1. J

    2024 US Presidential Election

    A British commentator on the radio suggested that Ukraine’s strategy might be aimed at gaining a stronger bargaining position once the war ends. The idea is that it all comes down to negotiations. For example, after a ceasefire, Zelensky might propose something like, “We’ll return Kursk if you...
  2. J

    Xenon Pharmaceuticals' XEN1101 — Kv7 Potassium Channel Modulator

    I found a book in a secondhand shop a while back about securing funding for research in the UK scientific environment. I still have it, though it’s quite dog-eared now. One of the first rules in the book was: “Don’t work in isolation; network as much as you can.” Interestingly, this reminded...
  3. J

    2024 US Presidential Election

    You’re diving into a deep and complex topic—perhaps a bit removed from the focus on presidential elections. When I was younger and less thoughtful (though still foolish), I used to be mildly critical of the United States and the challenges faced by African Americans. But over time, I’ve come to...
  4. J

    Rinri Therapeutics

    Government restrictions on research can certainly be a barrier in Europe. However, in the States, they often circumvent such restrictions by conducting experiments in third-world countries. While this approach might not be entirely ethical, it’s not necessarily illegal. Companies could justify...
  5. J

    The Bionics Institute Claim They Have Found a Way of Objectively Measuring Tinnitus

    Just a Thought: At the moment, my tinnitus is screaming away and has been for the past month or so. This could be linked to various factors: the COVID and flu vaccines, exposure to loud traffic noise (like motorbikes), or worry and stress—I’m currently on the housing market. I thought to...
  6. J

    Prolonging Residual Inhibition with Eglumegad

    In layman’s terms, some tinnitus patients notice that their tinnitus briefly pauses after an external noise occurs. The goal, then, is to try and extend this pause for as long as possible – ideally, to make it permanent. As for me? I seem to have permanent tinnitus. Every few years, I notice it...
  7. J

    The Bionics Institute Claim They Have Found a Way of Objectively Measuring Tinnitus

    Oh dear! If that fell into the wrong hands—like those of governments or even non-government groups...
  8. J

    2024 US Presidential Election

    Regarding Donald’s proposal to deport immigrants... Why not reintroduce the necessity of self-sufficiency? In previous generations, there were no free benefits or welfare—you either worked or struggled to survive. On my first visit to the United States, I noticed that the latest arrivals were...
  9. J

    Working Towards Better Healthcare Interventions for Tinnitus: a Brain Stimulation StudY (WHITBY)

    Why am I writing this? It’s all part of “The Science of Everyday Experience.” Tinnitus may be much more connected to stress or emotions than we realize. Case in point: myself. Last June, we received notice from our landlord, who plans to sell the house. It was a shock at first, but life goes...
  10. J

    Prolonging Residual Inhibition with Eglumegad

    @IYliKe & @RunningMan, thank you.
  11. J

    2024 US Presidential Election

    Trump wasn't my choice, but the eternal optimist in me – always looking on the bright side – finds relief in the decisiveness of the vote. America made its choice. No hanging chads, no bulging tabs, or whatever you call them; no disputes over voter authentication or stuffed ballot boxes. Sure...
  12. J

    Prolonging Residual Inhibition with Eglumegad

    I know I might come across as ignorant, but could someone kindly explain what “residual inhibition” is? It seems like there’s a real need for a dictionary or glossary on tinnitus-related terms.
  13. J

    Frequency Therapeutics — FX-345

    Is it a class-action suit that’s being considered? I know a lot of people here jumped in during the boom period. My opinion? I’d leave it to the American lawyers. Many of these cases are settled out of court, and the legal environment in the U.S. is entirely different. Just keep in mind that...
  14. J

    2024 US Presidential Election

    You expressed it much better than I did in my somewhat clumsy attempt a few posts back. Democracy, respect, and tolerance; they are all interconnected and are what made America, Europe, and the West prosperous. Out there in the more remote regions, they have only dictators and emperors. Every...
  15. J

    2024 US Presidential Election

    A quick reflection on recent history: remember the “Arab Spring” a few years back? That’s how democracy operates in places like Tunisia and Afghanistan. It started when a fruit vendor, denied a permit renewal in an arrogant manner, tragically took his own life. The population, fed up, erupted in...
  16. J

    The Bionics Institute Claim They Have Found a Way of Objectively Measuring Tinnitus

    The thought occurred to me the other day: We know that there seem to be several types of tinnitus. There are different responses among tinnitus sufferers to the same treatment: some improve, some get worse, and some are even cured. Once the Bionics Institute puts its machinery on the market...
  17. J

    2024 US Presidential Election

    All generalizations are false—including this one! But don’t let that ruin the excitement. It’s a cliffhanger, and all our destinies are “up for grabs,” for both U.S. and non-U.S. citizens alike.
  18. J

    Frequency Therapeutics — FX-345

    Just for the sake of completeness, we all contribute to medical research. The government collects revenue through duties on things like beer, gas (petrol), income taxes, capital gains, and probate taxes. Then, a government agency or committee decides how much of those funds will be allocated to...
  19. J

    Investigation of the Effectiveness of Sound Enrichment in the Treatment of Tinnitus Due to Hearing Loss

    Perhaps this is an indicator of the current direction tinnitus therapy is headed. It involves finding an ENT who can accurately diagnose the type of tinnitus you have and recommend the most suitable therapy. If they can’t completely cure it, that’s unfortunate, but it would still be the next...
  20. J

    2024 US Presidential Election

    Well, it’s not like I’m an expert. 🙄 But why don't y'all keep outa this. It's nunna yer bizness. The decision ultimately falls to the swing voters in battleground states—middle-class suburban housewives in Pennsylvania, Black and Arab-American men in Detroit, Michigan, and blue-collar workers...
  21. J

    2024 US Presidential Election

    Some news reports from Europe say that the latest polls are incredibly tight, with Donald slightly ahead of Kamala at this point. Well, there are still three weeks to go, and as we all know, a week is a long time in politics. But when it comes down to it, even if Donald gets more votes, it...
  22. J

    Cilcare's CIL001 Targets Cochlear Synaptopathy — An American/French Collaboration

    It would be nice to join the “optimism fest” and “hope bash.” It even makes some sense that fixing the synapses could alleviate tinnitus. After all, the synapses are like connecting cables that link the hearing nerve on one side and the hair cells on the other. If this approach works, plausible...
  23. J

    2024 US Presidential Election

    Some miscellaneous points: Russia threatening to nuke Europe? Nothing new there. Haven’t they been doing that since the 1950s? People getting all worked up? Well, we’re coming to the final stretch. Donald may have the advantage of experience, being male, and possessing a certain charisma, but...
  24. J

    Cilcare's CIL001 Targets Cochlear Synaptopathy — An American/French Collaboration

    Hey, am I missing something? I thought that phase one trials were meant to prove safety and phase two trials to demonstrate effectiveness. Where have I gone wrong, or what’s the reason for all this optimism?
  25. J

    The Bionics Institute Claim They Have Found a Way of Objectively Measuring Tinnitus

    I must confess that I don’t see the difficulty here. I see that you (Tinnitus Onset 1991) are one "year" older than me. The folks in white coats would simply measure the initial tinnitus loudness at onset, and then, as the years go by, take new readings to track its progress. No need to...
  26. J

    Chit Chat and All That...

    Don't worry, Elmer. You'll find that Italy has been waiting for you all along, once you've been cured. I’m a big fan of Italy myself, but at one point, I had to say to myself, Hey! This place is just too darn loud! Picture this: teens zooming past on Garelli scooters, right up on the sidewalks...
  27. J

    The Bionics Institute Claim They Have Found a Way of Objectively Measuring Tinnitus

    Thank you, @Nick47, for the optimistic note today. As I’ve mentioned in earlier posts, this could be the major contribution—our generation's big step forward, or rather, our era's step forward—in cracking the mystery and, hopefully, eventually delivering a cure for tinnitus, hyperacusis, and...
  28. J

    Frequency Therapeutics — FX-345

    I've ruined my eyesight following the twists and turns of FX-322, so please excuse me for not having gone through this entire thread on FX-whatever. ☕ But I noticed that their stock — if that’s any indication — has fallen from around $90 in April/May down to $31 today. What made them so...
  29. J

    Electrical Stimulation of the Cochlea for Treatment of Chronic Disabling Tinnitus

    Ahem... I take it that your statement implies skepticism :cool: That is a very impressive scholarship, @Nick47. How long did the tinnitus suppression last? Was there a control group and a placebo group in the study? What were the success and failure rates? Was the tinnitus chronic or early...
  30. J

    New Switch Mechanism Found That Triggers Tinnitus (Brai3n)

    I'm not sure whether this post belongs in the Bionics Institute thread or here, but an idea occurred to me—and a person has to think, right? Especially when you have that constant ringing in your ear 24/7/365. If or when the Bionics Institute gets their system up and running, allowing them to...
  31. J

    New Switch Mechanism Found That Triggers Tinnitus (Brai3n)

    The boys in white coats are getting closer, then. What’s that phrase? It’s all about location, location, location. :bookworm:
  32. J

    New Switch Mechanism Found That Triggers Tinnitus (Brai3n)

    It’s nice to hear some good news! Of course, we are all hoping this leads to a “fix” that is not too invasive, not too dangerous, not too far in the future, and not too expensive. I also hope they find the trigger for hyperacusis and reactive tinnitus, too.
  33. J

    New University of Michigan Tinnitus Discovery — Signal Timing

    Somehow, I'm cheered by the simplicity of your summary — but let me just play that through one more time. The source... well, in my case, it was likely triggered by noise, which I suppose affected the DCN (dorsal cochlear nucleus) and fusiform cells. Unfortunately, my tinnitus is reactive, so...
  34. J

    2024 US Presidential Election

    Jeeeehoshaphat! I commend you for your brilliant observation. Incidentally, could you explain for those who may not be well-informed: Is the Pope an atheist, Jewish, Buddhist, or something else? :joyful:
  35. J

    The Bionics Institute Claim They Have Found a Way of Objectively Measuring Tinnitus

    So, if I understand correctly: The subjects would hear nothing if the cochlear implant device was turned off—meaning they would be deaf and could only hear the tinnitus. Measurements were then taken of the dorsal cochlear nucleus in the brain, as well as the neural networks. After that, the...
  36. J

    2024 US Presidential Election

    You don't appreciate canine or feline in your Chow Mein? Clearly lacking in Cultural Enrichment!
  37. J

    Along the Road of Life

    A shot in the dark, Elmor, but I'll be looking for accommodation by the end of the year. How much is he asking for it? Is the location in Co. Wicklow—am I correct? You’ll understand that now that the students are back, anything resembling four walls and a roof is in high demand. :oldman:
  38. J

    Along the Road of Life

    It seems we're at a similar stage in life, or not far apart. During the COVID-19 lockdown, when we were all confined to our homes, I spent a lot of time sitting and reading—something that, in hindsight, isn’t the healthiest habit. However, I also taught myself how to bake bread, which felt like...
  39. J

    2024 US Presidential Election

    Now, I'm an outsider—at one stage in life, I could have become a US citizen. But after listening to interviews with both Kamal and Donald, I would be hard-pressed to decide which one is better (or worse). That being said, I know it's a matter of destiny for us all.
  40. J

    Along the Road of Life

    Well, Elmer, one thing is for sure: you've done the right thing at each step of the way. Prevention is the best approach when it comes to tackling cancer, and all hope is not lost. They may have found it before it had a chance to spread. I hope everything works out well for you and Mrs. Elmer...
  41. J

    2024 US Presidential Election

    What's that line of poetry? "Arguments that cannot be proven." One thing is for sure: whether the COVID-19 virus was released deliberately or by accident, the person responsible isn't going to step forward and take the blame. The Western mainstream media has largely blamed China for obstructing...
  42. J

    2024 US Presidential Election

    Listen here, Elmer! You really do sound Be(Fuddled) with your comment. The monkeypox virus is spread through skin secretions, as well as bodily fluids that can linger on surfaces. It doesn't discriminate based on whether the person is gay, straight, impotent, or even prepubescent. As for the...
  43. J

    2024 US Presidential Election

    Kennedy out? How will this affect the polls? There will likely be more increases for Donald than for Kamala, and of course, there will be more no-shows.
  44. J

    2024 US Presidential Election

    Oh, Daniel, I never knew you were Jewish/Muslim. :)
  45. J

    Electrical Stimulation of the Cochlea for Treatment of Chronic Disabling Tinnitus

    This is quite surprising -- if the success rate figures turn out to be true? Is it all about money? Sometimes, in medicine, it's fear of a bad outcome and a lawsuit... which comes down to money, too.
  46. J

    2024 US Presidential Election

    I'm sorry to hear that things are getting out of hand in the U.S. Since Biden stepped down, he's essentially just "keeping the seat warm" in the White House until Kamala or Donald takes over. I think it's time to start examining her stance on issues and how she might handle them.
  47. J

    Chit Chat and All That...

    Hang in there, @tpj. We all go through bad phases. I'm on a spike myself now -- since the landlord served notice to quit :(
  48. J

    Introducing Tinnitus Quest

    People come and go, and I wish you all the best. I completely understand your desire to distance yourself from tinnitus matters, as it may help you "put it in the background." However, it's important to remember that we are stronger together. If we all choose to suffer in silence, those...
  49. J

    Sound Pharmaceuticals (SPI-5557 & SPI-1005)

    You're spot on, Gumbo. Research and experiments are inherently optimistic, simply by existing and being put into action. What really excites me is when concepts evolve or expand in some way. For example, the discovery paper on hidden hearing loss and its influence, or Susan Shore's shifting...
  50. J

    Sound Pharmaceuticals (SPI-5557 & SPI-1005)

    I'm the opposite: My tinnitus spikes from a head cold, sore throat, and fever. And that's not all the triggers. Usually, it's noise.
  51. J

    New University of Michigan Tinnitus Discovery — Signal Timing

    Excuse me, I want to keep the temperature down here, but if @linearb was cured, as I seem to remember reading, why would he want to go and get cured again? I apologize if I have got my wires crossed, i.e. got confused.
  52. J

    New University of Michigan Tinnitus Discovery — Signal Timing

    I agree with you to a certain extent: Progress is usually made through the contributions of many individuals. The steam engine was invented around the time of the Roman or Byzantine Empire, but it was initially designed to open and close a door, or so it is said. In 1700s England, they...
  53. J

    New University of Michigan Tinnitus Discovery — Signal Timing

    No offense intended. As a matter of fact, @Nick47 viewed my smiley message as humorous, just as I had intended. On another theme, I had written myself off from the Auricle device as I can not easily change the volume of my tinnitus by moving my jaw/neck. However, a few mornings back, just as I...
  54. J

    New University of Michigan Tinnitus Discovery — Signal Timing

    Right again! How do you manage it? :cautious:
  55. J

    Chit Chat and All That...

    Ummmm... how would I put it? It isn't linear. You might have a high-temperature reading, but if there's no humidity (so dry heat), it's not so bad -- in the shade, at least. Likewise with cold: it could be -20 to -30 degrees Celsius or Fahrenheit, but if you are well wrapped up and there is no...
  56. J

    2024 US Presidential Election

    It's perturbing that some incident somewhere in the Middle East might sway the battleground states to vote this way or that and ultimately decide the fate of the Presidency. The latest bombardments in The Golan Heights, Beirut, and Teheran. Will they nudge the voters toward Trump & Vance or...
  57. J

    Chit Chat and All That...

    :bookworm: Will that goddamn fire engine turn the ringing off.
  58. J

    2024 US Presidential Election

    The latest from the Donald (addressed to the Taiwanese): "Pay for your own defense." Well, he's got a point, hasn't he? Nevertheless, why does it make me smile?
  59. J

    Cilcare's CIL001 Targets Cochlear Synaptopathy — An American/French Collaboration

    Spot on! It went under the name of Regain... or, in the link above, Regain Consortium.