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I’m not entirely sure how the active treatment group differs from the group in the first study. The results here are not as impressive but still promising—a nearly twofold reduction in volume after six months. Let’s hope he finds something that works, at least for those with residual inhibition...

I've considered asking a sound engineer I know about creating sound therapy based on the study. However, from what I understand, the published text of the study doesn't provide enough data on how the sound was processed to develop the therapy

Yes, I wrote to him in both English and Turkish. He replied to me in Turkish, but it took about a week for him to respond. ResearchGate: Eser Sendesen He is a young scientist specializing in tinnitus who has published several scientific papers on the subject, referenced by other researchers...

I e-mailed the author of the study. I asked if I could send my audiogram and use it to prepare audio therapy based on his study. Or would I need to be there in person? I wrote that I am ready to pay for such a service, if it is possible. I also specified that my hearing loss is related to...

The results are very impressive. The program used in the study to create the therapy (Praat program) seems to be free and available for download. Methods A total of 96 patients with chronic tinnitus were included in the study. Fifty‐two patients in the study group and 44 patients in the placebo...

A couple days ago I took 10 Ambroxol tablets of 30m g (300 mg total) at a time, 3 times a day (900 mg total for the day). I didn't feel any change in my tinnitus. There were no side effects either.

I recently underwent a series of tests, and fortunately, my neck is fine, with nothing abnormal showing on the MRI. The issue likely stems from my brain, possibly as a result of taking benzodiazepines and antidepressants. If it's not a problem on your end, I could send the medication for free...

I am the person who took the Iranian drug for two weeks. Since February, I have not decided to try the treatment again, although I currently have six jars of the drug at home (I asked several friends to bring it from Iran at the same time). After taking this drug, I also took Nettle (Urtica...

AI-powered neurotech developer Elemind emerges from stealth with backing from Bezos, Gates It’s electric! A startup emerged from stealth this week with grand plans to pioneer a new form of neurotech dubbed “electric medicine.” Elemind’s approach centers on artificial intelligence-powered...

SPIRE Deploys Effective, Safe Ultrasonic Neuromodulation Device SPIRE, an early-stage company spun out from the University of Utah, was established to produce controlled deep brain neuromodulation for chronic pain and depression. Its primary device, DIADEM, delivers low-intensity focused...

I thought it might be helpful to start a thread where we can share news from science, medicine, and technology that directly or indirectly relates to potential treatments or diagnoses for tinnitus. This could include information about new drug delivery methods, treatments for conditions related...

Hello dear friend, have you heard of this: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665825/ Kampo medicines are traditional herbal formulas prescribed in Japan. Recently, Kampo medicines, such as Kamishoyosan (KSS) and Kamikihito (KKT), were found to improve the stress-induced reduction...

No changes immediately after taking it. No changes after 2 weeks of continuous use. Tinnitus is the same volume, sometimes it feels that it has even become louder. It seems that there is a deterioration in my general health; fatigue has appeared, the fog in my head has become stronger, and my...

I finally received it. Starting to take it today, hoping for a miracle. I’ll keep you posted.

Another clinical trial where they combined audio with electric stimulation. → The Effectiveness of Microcurrent Stimulation Combined with Sound Therapy for Tinnitus Relief: A Preliminary Study

This is what I’m afraid of; of course, the reliability of research from a country like Iran is questionable. Today I started taking all the components in separate capsules. I still haven’t received Neurotec from Iran. I'll keep you posted on the effects.

I have ordered this product from 6 different people, but unfortunately I have not received it yet. We live in such an ugly world, where it is almost impossible to get a simple product from a neighboring country. I am still waiting, not giving up hope. While I am waiting, I decided to order...

Unfortunately, I did not find an online store where I could order the drug. I live in a country bordering Iran, I have already ordered it from friends who travel there, they should bring it to me soon. I will write here about how the drug works, and if there is any real benefit.

Another e-mail from Nu Eyne team. I checked with them about the first study and inquired about the amount of funding needed:

The treatment will not help everyone who is deaf. It applies only to one specific cause of deafness at birth: a defect in a gene that produces a protein called otoferlin. The inner ear contains about 16,000 hair cells, so called because they have comblike extensions that vibrate to different...

I found a drug with this compound, I'll try to order it and give it a try. It's made in Iran.

I just emailed NU EYNE and got this answer:

I too was confused that the device in the study looks nothing like the product on their website.

It's not a great graph, but from what I understand it shows that Phase 1 and 2 clinical trials for their tinnitus device are complete. I think they have a different device for migraines. ELEXIR is the treatment device for migraine: → https://nueyne.com/en/product/product05.html BEETHOVEN is...

NUEYNE-T100 is yet another device using both electrical and auditory stimulation, from a Korean company. NU EYNE researches and develops the treatment protocol for tinnitus by combining the approaches of auricular vagus nerve stimulation and sound therapy in synchrony. NUEYNE-T100 Tinnitus...

No, I haven't tried Carbamazepine yet.

As I understand from these tables, the effect of SPI-1005 on tinnitus is the same as that of placebo:

Not sure if this has already been posted here. According to the Phase 1 study results, SPI-1005 is not more effective than placebo in the treatment of tinnitus (taking into account both TFI scores and tinnitus loudness): SPI-1005 for the Treatment of Patients With Meniere's Disease

I took Carbamazepine for 3 days, one tablet at bedtime. My sleep improved and tinnitus at night was drowned out by about half. In the morning after waking up, for a couple more hours I felt the tninitus was muffled, after which it returned to the baseline. I borrowed just 3 pills from an...

I just took 3 tablets of 30 mg Ambroxol. It seems to make my tinnitus temporarily worse. :(

Why do you think the Clonazepam and Olanzapine are responsible for bringing the noise down?

Rosemary grows in my yard. I just tried it. It did nothing for my tinnitus.

Positive results from Duearity's user study on people with tinnitus

It looks like media is starting to pay attention to the study:

Before my tinnitus, me and my wife saved and adopted more than 500 stray cats and kittens, sterilised more than 50 stray cats, and cured many. Now unfortunately I can't do it anymore but my wife is still rescuing, I hope to join her again some time in future. At the moment we have 3 cats at home.

Otosclerosis is in the exclusion criteria list: SPI-1005 for the Treatment of Meniere's Disease (STOPMD-3) Exclusion Criteria: History of otosclerosis or vestibular schwannoma.

WOW! That would be just incredible! It's almost a superdrug then. Can you please share a link to the material where you saw that?

→ Sound Pharma completes enrollment in pivotal Phase 3 clinical trial of SPI-1005 for the treatment of Meniere's disease involving hearing loss, tinnitus, and dizziness