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  1. fletchermunson

    Rinri Therapeutics

    Does anyone have an idea what their “surgical procedure” would entail to receive their treatment? At least a day in the hospital? Would this hamper widespread availability of their treatment?
  2. fletchermunson

    Frequency Therapeutics — Hearing Loss Regeneration

    I’m just offering the information. Looks like their remyelination program had even less teeth than the hearing program. How sad and disappointing for those with MS.
  3. fletchermunson

    Frequency Therapeutics — Hearing Loss Regeneration

    Korro Bio and Frequency Therapeutics Announce Merger Agreement Merger to create a Nasdaq-listed genetic medicines company focused on advancing Korro Bio’s wholly owned portfolio of RNA editing programs Lead program is a disease modifying therapy for patients with alpha-1 antitrypsin...
  4. fletchermunson

    Rinri Therapeutics

    Rinri Therapeutics' Board of Directors still seems to be filled with biotech industry folks, right? Even Frequency Therapeutics liked to mention their connections to Harvard and MIT. I suppose the hope here is that Rinri Therapeutics do not become publicly traded so as to not puff up their...
  5. fletchermunson

    Frequency Therapeutics — Hearing Loss Regeneration

    Would all of the FX-322 IP be owned by Astellas at this point?
  6. fletchermunson

    Frequency Therapeutics — Hearing Loss Regeneration

    Right, no proof IN humans but it did regenerate hair cells ex vivo human tissue in a lab. And the drug made it into the cochlea. Did it regenerate in vivo? We do not have proof it did but there’s good reason to suspect it did. But no hearing was regenerated. Perhaps the synapses didn’t...
  7. fletchermunson

    Frequency Therapeutics — Hearing Loss Regeneration

    We know FX-322 regrows outer hair cells. It’s just that a hearing signal didn’t return. Is it possible that the synapses didn’t reconnect? This would be contrary to that old Stanford video which said they reconnect “like magic.” I wonder if any group is out there thinking about an FX-322 and...
  8. fletchermunson

    Famous People with Tinnitus

    I saw this story today about Nick Cave and it lifted my spirits. Hope it does for you too. Nick Cave discusses “the musician’s curse” of tinnitus: “It’s a pain in the arse”
  9. fletchermunson

    Frequency Therapeutics — Hearing Loss Regeneration

    A skin cancer diagnosis and recovery story of one of Frequency’s founders, Jeff Karp: Harvard scientist's 'doorknob' question leads to skin cancer diagnosis
  10. fletchermunson

    Pipeline Therapeutics

    When I clicked on the info button, it says this is done to delay submission... unless I’m missing something.
  11. fletchermunson

    Pipeline Therapeutics

    Not sure why, but on PIPE-505’s ClinicalTrials.gov page, the company has filed for an extension to release the results of last year’s trial.
  12. fletchermunson

    Pipeline Therapeutics

    Pipeline Therapeutics Appoints Eef Schimmelpennink to its Board of Directors
  13. fletchermunson

    Pipeline Therapeutics

    I noticed today that PIPE-505 is listed as being in Phase 2 on the Pipeline Therapeutics website. How long has it been like this? Has there been an official announcement?
  14. fletchermunson

    Otonomy OTO-313 — Treatment of Tinnitus

    Would OTO-413 help you then?
  15. fletchermunson

    Frequency Therapeutics — Hearing Loss Regeneration

    I have this same problem. I took the diuretic and it helped. But I also had an MRI that confirmed I don’t have hydrops or Meniere’s. I’m not sure what is going on. Might just be a distortion form of tinnitus.
  16. fletchermunson

    Frequency Therapeutics — Hearing Loss Regeneration

    Hi Everyone. Long time listener, first time caller. To begin, I’d just like to say that I am very grateful to everyone on this forum sharing their hopes, fears and general information. It’s been a great source of relief to me over the years… optimistic and pessimistic alike. A few lingering...