Search results for query: neomycin

Hi Greg, 1. I’ve been on Mirtazapine since September 2018 2. I’m not sure what contrast it was, I know I had to sign a consent form and when it was released I felt warmth throughout my body, it made me feel as if I peed myself, I was warned it will feel like that 3. No itchiness I heard the...

...inhibition of HDACs using trichostatin A (TSA) or valproic acid (VPA) increased histone acetylation in the regenerated neuromasts following neomycin-induced damage. We also showed that treatment with TSA or VPA decreased the number of supporting cells and regenerated hair cells in response to...

...known to cause permanent loss of hearing, dizziness, etc. I am scared and I don't know what to do. I already took Sofracort which is neomycin and gramicidin with a steroid for 10 days. So why would a different antibiotic in the same class work? So I'm pretty much out of options for...

...of the best ways to treat and cure hyperacusis. Again, please read all my posts in this thread. On your Avatar is reads: Cause of tinnitus Neomycin? My understanding this is an antibiotic and if this caused your tinnitus, then it wasn't noise induced and therefore you may not have...

I'm so very sorry you are going through this. I think we all wish we could turn back time in regards to our tinnitus. If we had only done this or that, but truthfully it was probably a combination of things that caused our tinnitus. I encourage you to read the success stories. Some members...

...soften the earwax before having it removed, this could have aggravated the tinnitus that was already present or caused it to develop. The Neomycin ear drops could also be responsible for causing your daughter's tinnitus as it can have side effects. This medicine is an antibiotic and...

...such as aminoglycosides should be avoided if possible. These will normally have names that end with -mycin or -micin (e.g., gentamicin, neomycin). Aminoglycosides can be found in some antibiotic ear drops, as long as the ear drum is not perforated these should be safe to use but do so with...

...any troubles with my ears as I am only 17 but I do have really small ear canals so wax builds up quickly. My family doctor prescribed me "Neomycin Polymyxin B Sulfates and Hydrocortisone Otic Solution" but it only helps a little bit. Will this ringing noise ever go away? I've stressed...

While it is theoretically possible for neomycin ear drops to cause damage, it is very unlikely with a single dose even with a perforated ear drum. It is more likely that the tinnitus is due to the perforated ear drum or the anxiety about all of this. You may also need to get a different...

...my brain or something super serious so I went to the ER. The doctor kept assuring me my brain was fine and gave me a prescription for... Neomycin eardrops!.. I have medication anxiety and usually question everything but I was so afraid of infection that I used the drops one time. Then I read...

...and loud. I refused to do it again. I am afraid it did more harm than good. But I can't be sure. A spike had began last week using the neomycin drops for five days then when I went back for a hearing test, my right ear which was always quiet started acting like the crappy side. I need...

Give it a few days and see how you feel. if your ears are still poor, then go see an ENT and an audiologist. Your tinnitus could be short lived, just see how it goes. Don't panic, it is not the end of the world, you will make it.

The unfortunate naming issue is that both aminoglycoside and Macrolide antibiotics end in -cin so they sometimes are lumped together. However as @Nucleo said aminoglycoside antibiotics are known to be ototoxic. For example, from http://www.ncbi.nlm.nih.gov/pubmed/17266591 Even though they end...

...The general rule with ototoxic drugs and chemicals however, is that they're only really harmful when introduced directly to the ear (think Neomycin for outer ear infections) or intravenously. While there may in fact be ototoxic chemicals in hand gels and sprays etc. the dermal absorption...

...also contain trace amounts of antibiotics. And they are of the "mycin" variety. This year, according to the CDC, trace amounts of Neomycin will appear in vaccinations. Last year, I did get the flu vaccination and my tinnitus became scary loud, but only for one day. But I felt the...

...to people with perforated eardrums!!! In the cases of those who developed a permanent increase in tinnitus after being administered, say, neomycin ear drops ... the increase was due to the infection that resulted in the prescription rather than to the prescription itself. Unless, of course...

...not sure its worsened as a result of further hearing loss, or because of the abs or infection or all three? I was inititally prescribed NEOMYCIN drops, which I later find out is highly toxic. I used this for one day before discontinuing. The t seemed louder before I started any of the abs so...

Ototoxicity depends on the ototoxin and is unique with each one. With aminoglycoside antibiotics (what this thread is about), you almost always see audiogram changes because it damages outer hair cells. Sometimes, you will see the damage in the ultra high frequencies first. A 5 dB dip is normal...

...to help clear my sinuses. He also prescribed a nasal spray to help decongest my sinus, but it included Betnesol-N, which contains neomycin, which I see is an ototoxic antibiotic. I'm not sure what effect it will have on my ears if I spray it up my nose, so I've just not used it at all...

Interestingly, in the paper @annV just linked (you rule as always), it describes one of the functions of VPA as increasing LGR5+ expression so that more support cells can be used as progenitor cells. The paper also talks about the synergistic effects of notch and wnt co-activation on hair cell...

...clinic in very rural Maine I only saw a nurse who thought it was swimmers ear witch made sense I have been in the water a lot she prescribed neomycin and polymyxin b sulfates and hydrocortisone otic suspenion USP drops that I have only taken twice, the night i got them and this morning. She...

...blister and put a band-aid on it. Sat for a short while reading and then looked at the contents of the gel I'd put on and read that it had neomycin in it. Came across a few posts about how ototoxic that can be, even in topical form and then promptly washed it off. Ears have begun to feel...

...all for about a week by the time I had the tests, they actually did loudness discomfort test as well, I was out of my mind anxious, and I used neomycin topical ointment as well, and high dosage of Piracetam and Betahistine. Maybe all of this contributed to develop the bilateral tinnitus as well.)

Apologies if there are grammar mistakes, as a Chinese speaker, English is my third language. I developed my T after a neomycin ear drop treatment with a ear drum perforation. Neomycin - the most ototoxic one in aminoglycosides group. A stupid decision from my GP in New Zealand, led to a life...

I believe in one of the preclinical FX-322 tests they used cochlea that were removed from the mice then soaked in antibiotic to kill the hair cells then soaked in FX-322 to regrow them successfully. Based on that anecdote ototoxicity patients may have cause to be optimistic.

Hey Zimichael, how often do you get spikes and do they settle to baseline by the next day? I've had a few spikes in the last week, although I have the impression they are happening with less regularity and the spike is not lasting long, sometimes seconds to minutes of course if you exclude last...

...did to my grandmother and read a ton about how truly awful C Diff is and was very anxious about not getting it. How ironic that I considered Neomycin safe for clostridium and it's one of the most ototoxic antibiotics. I hope that none of us will ever need it, but have you considered fecal...

...I got it on a Wednesday and went to urgent care on Saturday. The doctor (nurse) said it was probably an infection and gave me Augmentin and Neomycin drops. About 3 days later, not feeling much better, I went back to urgent care. This time the doctor gave me a steroid injection and a...

Ear canal, I assume...? I would still classify this as otitis media or infection of the middle ear. The first thing any doctor will do is examine the eardrum to see if the eardrum is intact. If so, I doubt that the ototoxicity of any eardrops is particularly relevant. But... I also admit that...

Hi! Yes I have had blood work and all is good. I was not overweight, I was 245 body builder, lost mostly muscle. I am pretty sure my ears are still in the healing/damaged state from the meds. Every time I encounter a loud noise they seem to get worse, maybe sick hair cells dying off, I don't...

I had occasional tinnitus, got double ear infection, went thru a bottle of Neomycin based ear drops, the infection was cleaned up then all a sudden this high pitched piercing sound lance from hell shot through my head in one ear and out the other. It has never left for 4 years. 7800 Hz a...

Hi. My tinnitus jumped up to I could say a 7 or 8 last Thursday. Could have been from taking Gentamicin and Neomycin eye drops, could be idiopathic or part of the progressive hearing loss I was diagnosed with as a kid after having bacterial meningitis as a baby. Saw the audiologist and ENT. I...

...As far as I know, only Augmentin and Amoxicillin are regarded as generally safe among the more frequently prescribed antibiotics. I had the bad luck of applying a Bacitracin/Neomycin sulfate ointment on a burn wound for nearly two weeks. I am still dealing with the tinnitus spike that it caused.

How are you feeling right now? Are you conditioned to it? Did it get better in time?

I don't think aminoglycosides would complete decimate support cells but i wouldn't take a support cell depleting drug (e.g.. Audion). Support cell loss, like hair cell loss is usually a gradient so if you have HF loss, you lose more support cells near the base. So FX-322 will definitely help...

...through topical administration and I will not risk my body reacting further. But that’s not to scare others out of using them. I know countless people use them without these effects. That’s just my experience. And as far as tinnitus goes, it is indeed the safer option vs using the neomycin...

I was given Nystalocal cream for fungal infections but I doubt the infection is fungal. After the first application I had on off burning and pain. I'm going to discontinue it due to the burning as it writes on the leaflet. I can't put any drops in my ears. I read somewhere that otitis externa...

Hey! First of all - we all understand you pretty well here (more or less). Could it get better - yes. Will it? Depends, but most of the time it does get better. How much better - no one can tell. I wish that we could give you more of a scientific answer here, but it is mainly speculation here...

...as Ear Drops (if i can recall correctly, dosage is 3x2 per day). I think it's the safest med i could got, my mother have some med but with Neomycin which is highly ototoxic so i refused to take it and got Cetraxal Plus from GP. If it's valuable information and it can interract with Ear...

...amplify Wnt/β-catenin signaling throughout the SC population. Methods Postnatal murine cochleae were exposed to the ototoxic aminoglycoside, neomycin, in vitro and then cultured under conditions in which Wnt pathway activation and inhibition of Hes1 signaling were alternately manipulated...

Hello FGG, Thank you for the very informative response. Much appreciated. I pray that the damage to my ears is only limited to OHC. I pray you are right with thinking we can get some improvement from these new discoveries. I am holding on to your words “I don't think that is at all an...

...ADP, Berberine and Dysbiocide approx 14 pills per day. Another breath test showed numbers went down, doc said you ready for Xifaxan and neomycin. After 3 days on the combination left ear starts to ring Next day prescribed prednisone for 8 days. 2 days later in emergency room with ringing...

...treated now by a subspecialist ENT for weeping skin in both my ears from otitis externa, caused by another Dr. who insisted on giving me neomycin ear drops and they messed me up big time! During the course of the last two months, this specialist has de-brided my ears (using microscope and...

Okay thankyou for that, im gonna try and not worry then say if i get strep throat, or the flu and have to take a mycin... Its crazy cause i havent needed an antibitoic since i was like 10 and that was 13 years ago.. I rarely get sick but im older now. I still wanna get rechecked for a...

How much and how long did you take the Azithromycin?

...one of them being guinea pigs having stem cells (10M) injected on day 3 after concluding a significant auditory insult as a consequence of neomycin ototoxicity. The authors of the study made use of staining: this allowed the scientists to observe that the stem cells indeed had migrated to...

...two days later, the muffled hearing and tinnitus returned. Now, I came across "otoxicity" in one of my internet wanderings, and read that neomycin (the "N" in PND) can cause it. Now for my questions: 1.) I've only used the PND drops about 5-6 times in a span of about 4 days. Would it have...

Same exact story. Holy shit. It’ll get better, give it time. I promise. Took me 6 months to see some changes.

My first post here after being a member for 2years, some of you already know my story I got my T from an neomycin ear drop 2 years ago. My T developed immediately to an unbearable degree after using ear drop with an undetected eardrum perforation. I have ultra high pitched hissing in both ear...

Hello Rich, When I read your honest and raw post I felt many things. But the first thing I think is that it has only been ten days. I say this because I am on a very similar timeline to you and I also have been having some dark thoughts and am full of regret/fear/remorse etc. But I can't seem...

...the bathroom). I also had hearing loss and the hissing got louder whenever some constant sound happened (faucet running, for example). Was given steroids, augmentin, and neomycin drops (also had otitis externa but the doc said it would also help for the om) around two weeks to completely go away.

Hi Debby. I'm late reading your post but I noticed it and had to comment! Sounds like you suffered a great deal of harm from those drops! Should've never been prescribed to you with a perforated eardrum. It got into the middle ear due to the perforation and can severely damage hearing and the...

...infected. He told me that I should get a ear wax removal kit for the left when I have the time. He also prescribed a Z-pack antibiotics, Neomycin-Polymyxin-HC Ear Suspension drops for the right ear and some codeine type syrup for my throat. Anyway's, that day, I didn't start the wax removal...

...without being also given the information to make an informed choice. Often for non life-threatening conditions. When I was prescribed Neomycin to go into my ear I directly asked my GP whether it might make my tinnitus worse and he told me it would not. But it did. If he had not given me a...

...In early November, I had a diagnosed external ear infection in both ears (much worse on my left) by 2 ENTs. I took a short 5 day course of Neomycin ear drops. My eardrums were confirmed intact before and after the course by ENTs. The second ENT ran a hearing test and I had no hearing loss. I...

...at the moment, which in turn will play havoc on your tinnitus. It does sound like you are very sensitive to medication, and you are right, neomycin is a nasty drug which can cause lots of issues for some and unfortunately hearing issues is one of the main side effects of this drug. Things...

I feel so cursed and this feels so unfair. Why is this happening like this to me? Did the neomycin just fuck me up THAT bad? Did I just expose to too much noise, not avoiding crowded places like Rennfest and getting an MRI? Did I just re-fry my brain too much with all the meds I kept trying and...

I'm no doctor but I would suggest calling the doctor back and see what he recommends. What you could also do as well is if the ringing hasn't gone away after a few days, go to a hearing aid place that does free hearing tests. Have them check your hearing and see how good it is. If you have...

...ototoxic medications include the aminoglycoside antibiotics when given by vein or by injection (e.g., gentamicin, streptomycin, amikacin, neomycin, tobramycin); the quinine-based antimalarials (e.g., chloroquine) and quinine-based antiarrhythmics (e.g., quinidine); and the platinum-based...

...find solutions to at least eliminate some of them. For context, before May 1st of 2019, I had ZERO symptoms. It all started when I took Neomycin on that day early in the morning. Slowly throughout the next 1 ½ year, I developed all this. I place the symptoms in somewhat of an order as they...