Search results for query: auditory brainstem response

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  1. Johan_L

    Objective Measurement of Tinnitus — ABR (Auditory Brainstem Response)

    ...are somehow involved. Short article: Constant Tinnitus Is Linked to Altered Brain Activity Long version: Alterations in auditory brainstem response distinguish occasional and constant tinnitus SUMMARY: BACKGROUND. The heterogeneity of tinnitus is thought to underlie the lack of objective...
  2. Frédéric

    Neuroinflammation Mediates Noise-Induced Synaptic Imbalance and Tinnitus in Rodent Models

    It is a pity the article is behind a paywall. Compared to this thread, similar parameters are acute tinnitus, the hypothesis of neuroinflammation, and rodents. Dissimilar parameters are noise-induced tinnitus instead of salicylate-induced tinnitus and Rolipram (an old drug) instead of TNF. →...
  3. EDDTEKK

    I Developed Typewriter Tinnitus After Having Regular Tinnitus for Six Years

    ...he said there was a high chance of improvement based on his experience. We conducted high-definition MRI scans and auditory brainstem response audiometry. Initially, the symptoms disappeared after taking carbamazepine, but unfortunately, the medication stopped being effective after about...
  4. Chezten

    I Developed Typewriter Tinnitus After Having Regular Tinnitus for Six Years

    I am seeing an interventional neurologist on November 12, 2024. My symptoms are getting worse with loud, rapid clicking in my left ear and a rhythmic sound in my right ear that matches my heartbeat. I hope to get some answers because I am not coping well at all.
  5. Tau

    Choice of Stem Cells

    No, my audiograms are actually fine all the way to 16 kHz. You need an auditory brainstem response test.
  6. StoneInFocus

    Nimodipine

    ...VGCC blocker was administered immediately before acoustic overexposure. The hearing ability was evaluated using the auditory brainstem response (ABR). ABR is an electrical signal evoked from the brainstem by the sound. After the final ABR measurement at two weeks after acoustic overexposure...
  7. patorjk

    Decibel Therapeutics

    I decided to dig around and see if there was any news from DB-OTO study and I found this press release from Regeneron that indicated some initial success: A placebo effect for this kind of hearing loss is unlikely, especially for a child that probably doesn't even know what's happening. I...
  8. star-affinity

    Otonomy OTO-6XX — Hair Cell Regeneration

    Wow, can you conduct a test to figure out if you have synaptopathy? I didn't know that. Would be interesting to know how I fare on that.
  9. FGG

    Frequency Therapeutics — Hearing Loss Regeneration

    Auditory Brainstem Response. It's how they test babies' hearing too. It gives you a general idea.
  10. N

    Treatment Prospects: Vagus Nerve Stimulation

    Nothing exciting. Animal study using VNS with and without audio versus placebo after salicylic induced tinnitus. Effectiveness of transcutaneous vagus nerve stimulation (tVNS) on salicylate-induced tinnitus
  11. Tau

    Auditory brainstem response. I managed to get to a good doc who knows her stuff. Minor...

    Auditory brainstem response. I managed to get to a good doc who knows her stuff. Minor abnormalities show neuropathy - IHCs/OHCs seem to be fine, but the signal does not reach my brain properly. And since it's noise induced, it's going to be synaptopathy as those are the first to go.
  12. erik

    The Reduced Cochlear Output and the Failure to Adapt the Central Auditory Response Causes Tinnitus

    ...synapses of the inner hair cell (IHC) as a measure for deafferentation; (2) the fine structure of the amplitudes of auditory brainstem responses (ABR) reflecting differences in sound responses following decreased auditory nerve activity and (3) the expression of the activity-regulated gene...
  13. Stayinghopeful

    Transcranial Stimulation Treatments (rTMS & tDCS & tACS)

    I’m excited for you! Can’t wait for the update.
  14. ErikaS

    Transcranial Stimulation Treatments (rTMS & tDCS & tACS)

    ...he also uses an auditory response test, which he says is very useful with cases like mine. I am not sure if it is an Auditory Brainstem Response test, I will confirm this with him when I speak to him again this week. I made it VERY clear that my goal is to calm reactivity and stabilize the...
  15. Frédéric

    Research's Attempt to Objectively Assess Tinnitus

    An umpteenth study about tinnitus and ABR, see attached file. Auditory brainstem response demonstrates that reduced peripheral auditory input is associated with self-report of tinnitus.
  16. Diesel

    Pain Hyperacusis in Relation to Acoustic Shock & Synapse Disconnection

    Does this seem relevant to this conversation? Within-Subject Comparisons of the Auditory Brainstem Response and Uncomfortable Loudness Levels in Ears With and Without Tinnitus in Unilateral Tinnitus Subjects With Normal Audiograms
  17. Fabrikat

    Inner Ear Hair Cell Regeneration — Maybe We Can Know More

    I believe there is a test audiologists use called an Auditory Brainstem Response, which can test retro-cochlear and brainstem involvement in hearing loss. It's common and often used to test hearing loss in infants, who are not able to respond to tone audiometry testing.
  18. Kleiner

    Frequency Therapeutics — Hearing Loss Regeneration

    I don't understand why Frequency Therapeutics hasn't added auditory brainstem response (ABR) testing and OHC emissions to its clinical trials. It's a bit amateurish to use only audiograms. That's what worries me the most. We just have to wait for the severe hearing loss trial. They will no...
  19. LostinTX

    Benign Paroxysmal Positional Vertigo and Tinnitus

    I'm curious what the treatment was? I understand ABR is a measurement, but what did they do with this information to help find "ischemia in the auditory pathways is suspected in BPPV formation"? When I got BPPV and then tinnitus followed 2 weeks later my "tinnitus specialist" doctor straight...
  20. Tiumix

    Tinnitus After Hitting Head in Attic

    Hello Gman45, I started developing tinnitus after a severe neck injury on 6/21/21. My first 5 months is almost exactly like yours in terms of fight or flight response, mental exhaustion, yearning for silence, hyperacusis. I'm 28 years old and been trying to cope with tinnitus too. My tinnitus...
  21. Tiumix

    Tinnitus and Medical School

    Hello everyone, I am 28 years old and I have an interview for a top 50 medical school in March. However, I'm worried that my tinnitus would distract/stress me too much to achieve my goal of being a doctor. However, I have a strong support system and will do my best towards that goal. Throughout...
  22. NikoD

    Akouos — A New Company Focused on Genetic Hearing Loss

    I was just about to post this but you beat me to it. From Lilly's website: This is potentially the BIGGEST news for hearing research in human history... I can't contain my excitement! Amazing if true, we might for the first time have a cure for sensorineural hearing loss... :woot: The bit...
  23. H

    16 kHz Hearing Loss — Intratympanic Steroids or Stem Cells?

    Yes that, but mainly the Auditory brainstem response test or whatever it's called. I think it's 90 dB sounds in headphones for an hour or so. Not exactly my idea of a constructive thing to do with my time :headphone:
  24. undecided

    Auditory Nerve Sedation for Correct Diagnoses

    Interesting... Any source for this? Who performs this procedure? I did a quick google search and I didn't find anything relevant... There is a wikipedia article about auditory brainstem response but that's not quite the same.
  25. Aaron123

    Inner Ear Hair Cell Regeneration — Maybe We Can Know More

    ...I don't have access to the paper so I don't know more than what is here. Auditory Brainstem Response Latency in Noise as a Marker of Cochlear Synaptopathy Abstract Evidence from animal and human studies suggests that moderate acoustic exposure, causing only transient threshold elevation...
  26. PortugalTheMan

    An Antibody to RGMa Promotes Regeneration of Cochlear Synapses After Noise Exposure

    ...an anti-RGMa blocking antibody regenerated inner hair cell synapses and resulted in recovery of wave-I amplitude of the auditory brainstem response, indicating effective reversal of synaptopathy. Hidden hearing loss results in compromised ability to understand words in a noisy background and...
  27. Tau

    Otonomy OTO-6XX — Hair Cell Regeneration

    ...I do, I hear stupid beeping sounds over everyday noise and music sounds like trash, but I do hear all the instruments. Auditory brainstem response test show that I have neuropathy/synaptopathy. Maybe there's a dead hair cell here and there, but I don't have big threshold shifts. So I am...
  28. W

    Can Wuling (Wu Ling Shen) Help Tinnitus? Here's a Promising Study

    ...damage in the auditory pathway of tinnitus rats, improves the ultrastructure of the auditory center, and lowers the auditory brainstem response threshold, thereby improving the auditory function of tinnitus rats and improving the anxiety and depression. The mechanism may be increasing the...
  29. FGG

    Inner Ear Hair Cell Regeneration — Maybe We Can Know More

    I don't have trouble with pure tone just complex sound. There is certain kind of KV 3 potassium ion channel involved in sound layering, esp dynamic sound. I was told ABR testing would look normal in my case regardless.
  30. Diesel

    Frequency Therapeutics — Hearing Loss Regeneration

    They used audiogram, WR and WIN because they are common clinical tests. These tests show what would be observed in a clinical setting.
  31. twa

    Tinnitus and Medical School

    @Tiumix, best to you on your application to med school. I am in doctoral program in a different field. I have talked to my physician several times about my tinnitus and he said he also has tinnitus. He does well with his practice and has said he has had tinnitus for several years. He has a happy...
  32. K

    Frequency Therapeutics — Hearing Loss Regeneration

    My ENT said it wasn't possible. I thought Otoacoustic Emissions test and Auditory Brainstem Response test were exactly the tests to help figure if your problem is from dead hair cells or from a damaged acoustic nerve. But maybe not? Like @tommyd87 said, i'ts very likely both hair cell and...
  33. Zechariah

    Autifony Therapeutics Phase II Study for AUT00063, for the Treatment of Hearing Loss and Tinnitus

    ...so no trials for me. But if the AUT00063 works on people with hearing loss it is more likely to work on people who don't. Btw, it would be horrible if you get louder T from those auditory brainstem response tests and in the end the medicine doesn't even work for you or generally :banghead:
  34. SmallRonnie

    Choice of Stem Cells

    I guess I'll have to ask my ENT guy about that test when I see him. I might just ask them if they'll treat me anyway. I have pretty bad reactive hyperacusis which leaves me in pain for weeks usually and tinnitus just for 3 weeks now non-stop where before I only briefly had it. If I don't see a...
  35. Reverse

    Low Frequency Tinnitus

    ...had me in their office about ten minutes and said well, if it's tinnitus, you're screwed, basically... Doctors did an auditory brainstem response test and hearing was perfect... I was given 1 gr IV Solu-Medrol for three days in March for the papillary edema that was the reason the lumbar...
  36. Frédéric

    Benign Paroxysmal Positional Vertigo and Tinnitus

    The evaluation of tinnitus and auditory brainstem response in benign paroxysmal positional vertigo accompanied by tinnitus Purpose The aim of this study is to investigate auditory brainstem response (ABR) in patients with benign paroxysmal positional vertigo (BPPV) accompanied by tinnitus and...
  37. N

    Tinnitus Models — Learn How Tinnitus Originates

    @HomeoHebbian, thanks for the thoughts on the current model and your optimism. Having listened to various researchers and having had a Zoom discussion with Dr. Dirk De Ridder, the research field seems scattered and sometimes with great conflicts of interest. We've all asked for collaboration...
  38. A

    Tinnitus for 26 Years with HORRIBLE Recent Change

    I just wanted to update that the ABR test stands for Auditory Brainstem Response Test. Do you not ever let anyone give you this kind of test , as for me, it was absolutely horrible and so terribly loud. I also wanted to add that I have been advised by ENTs and audiologists to continue to enjoy...
  39. B

    Experiences with Head Tinnitus?

    ...but many subsequent studies refer to this method. Since, it has been pointed out that it has its flaws and if I am not mistaken researchers nowadays rely on auditory brainstem response. We don't even know for sure if the animals have tinnitus. It's a good practice that researchers now rely on.
  40. rpalmquist

    ABR Test — Who's Had One, What Was It LIke, Was It Helpful

    Auditory Brainstem Response (ABR) Test is one suggested test/treatment for tinnitus. I'm interested in learning about your experience in this form of test to help me determine if I should get one, but couldn't find much detail in this form (thus this new thread). My background: -- Got T on...
  41. InfiniteLoop

    If Audiologist's Test Shows Hearing Loss, Can They Specify What Part of the Inner Ear?

    ...cells in the cochlea. If the tone audiometry hearing loss and the DPOAS are similar, then the problem is in the cochlea (the most common problem by far). They can perform ABR (auditory brainstem response) to check if there is a problem with the auditory nerve. This test is not very common.
  42. N

    Could a Memory Foam Mattress Cause Tinnitus?

    ...there has been overwhelming evidence that tinnitus patients with no deterioration of hearing thresholds have abnormal auditory brainstem responses, suggesting an homeostatic response to cochlear neuropathy. Such neuropathy can also affect the function of Outer Hair cells, as the efferent...
  43. Giuseppe90

    Tinnitus After a Plane Flight with Cold

    ...the condition of the Eustachian tube. He told me that the Eustachian tube is fine. He prescribed two types of tests, ABR (Auditory Brainstem Response) and an MRI of the petrous bone. He told me that the problem could be traced to a mandibular bone, so he advised me to see a maxillofacial...
  44. M

    Autifony Therapeutics Phase II Study for AUT00063, for the Treatment of Hearing Loss and Tinnitus

    ...and exclusion data. if i'm reading this correctly...you need to have 20db of hearing loss and less than 60db hearing loss. and you can't be anxious or depressed. and they do an auditory brainstem response at the beginning and end of the treatment which is around 80-85db and quite loud. well...
  45. d'Wooluf

    Frequency Therapeutics — Hearing Loss Regeneration

    ...system can present with hearing impairment. Characteristically, a reduction in clarity of hearing and speech comprehension is much greater than the loss of the ability to hear pure tone. Auditory testing shows normal otoacoustic emissions (OAE) and an abnormal auditory brainstem response (ABR)."
  46. frohike

    Cochlear Implant + Gene Therapy = Regrowth of Auditory Nerve?

    Is it just me or this is a huge breakthrough?
  47. Amber

    ABR Test — Who's Had One, What Was It LIke, Was It Helpful

    What are you looking to learn from the test? How could it help you?
  48. Giuseppe90

    Tinnitus After a Plane Flight with Cold

    I performed ABR (Auditory Brainstem Response). The results show normal values in both ears. In a few days I will have the MRI and the maxillofacial check. Now I'm starting to take 30 mg/day of Cyclobenzaprine for 12 weeks, my ENT told me that could help. I have a forceful crackle/pop every...
  49. Benjaminbb

    Low Frequency Tinnitus

    Do they know how CSF actually affects the ears? Does it do something to the nerves, brain or directly affect the cochlea?
  50. Frédéric

    Diabetes and Tinnitus — Is There a Link?

    Interpreting auditory brainstem evoked responses and distortion product otoacoustic emissions in diabetic patients with normal hearing Abstract Objective Hearing impairment is a reported late complication of diabetes mellitus (DM). Previous studies have suggested that microangiopathic...
  51. Reinier

    Inner Ear Hair Cell Regeneration — Maybe We Can Know More

    That is still not very accurate I would imagen. If this (@Aaron123 ) "Auditory Brainstem Response Latency in Noise as a Marker of Cochlear Synaptopathy" can be more accurate that would be wonderful. Developing this should not take an enormous amount of time? And tests are not invasive. I...
  52. Christiaan

    TU Delft & Prof. Dirk De Ridder — Bimodal Stimulation Device for Treating Tinnitus

    Valid point. Dr. De Ridder suggests in this article that the mechanism of vagus nerve stimulation (VNS), especially when paired with sound, is expected to influence the perceived volume of tinnitus directly, rather than hoping for an indirect or later effect. According to Dr. De Ridder, the...
  53. Danny Boy

    Acetyl-L-Carnitine Effective for Tinnitus?

    Tried it, didn't work, sadly.
  54. Stink

    Acetyl-L-Carnitine Effective for Tinnitus?

    ...otoacoustic emissions, tinnitus questionnaires (Tinnitus Handicap Inventory and Tinnitus Reaction Questionnaire), auditory brainstem response, functional MRI (fMRI), functional connectivity MRI, and cerebral blood flow evaluations were conducted before intake of ALCAR and were repeated 30...
  55. Matchbox

    Hyperacusis / Reactive Tinnitus / Hearing Distortion

    A neuronal tuning loss makes the most sense for us distortion peeps.
  56. Vaba

    Audiogram and Other Hearing Test Results

    ...first paper is another audiogram. Ignore the 12kHz dip, he didn't actually test that frequency. The next two are ABRs (Auditory Brainstem Response tests) which measure the my brain's response time and response strength to sounds entering my ear. Both ears respond in the same amount of time...
  57. dan

    Autifony Therapeutics Phase II Study for AUT00063, for the Treatment of Hearing Loss and Tinnitus

    Why would anybody bother to treat their tinnitus if they aren't depressed or anxious about it! wtf
  58. GBB

    Otonomy OTO-413 — Treatment of Hidden Hearing Loss

    I’d be willing to bet 10 dB of improvement would help substantially cut through tinnitus.