Search results for query: neomycin

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  1. Nonna

    Ear Keeps Popping and Hearing Seems Better

    Yes, if u mean like a bubble gum pop, i was asleep so it may not have been that loud. had two during sleep, and noticed right away my hearing was better. Wish I could get one more loud pop. I have a bunch of tiny ones now.
  2. C

    Frequency Therapeutics — Hearing Loss Regeneration

    My tinnitus and hyperacusis (loudness) is also the result of ingesting an ototoxin. In my case it was neomycin. I’ve had both since May 2019. I have no hearing loss up to 8,000 kHz. What treatment(s) would hold promise for me? Also, thank you for recommending getting an expanded audiogram in an...
  3. SoulStation

    Sudden Onset Tinnitus in One Ear

    I would not use that. It is an aminoglycoside antibiotic. They are known to be ototoxic and with the off chance that your ear drum is ruptured you don't want to damage your ear .
  4. linearb

    Still Really Annoyed With My Doctor!

    Interesting; I did not realize that some of the aminoglycosides do get the mycin suffix, so I am wrong about that. That makes the suffix itself seem pretty worthless as far as evaluating ear risks. Geg, do you know which drug it was? Was it a pill, or drops? An unfortunate reality is that...
  5. Zimichael

    How Did Your Hyperacusis Start? Has It Gotten Better?

    See my Profile for details... Basically prior tinnitus only, then ototoxic meds added the H. And clearly the meds, no iota of a doubt. (Neomycin and then Amphotericin. Oral not IV). P.S. Please let us know when you start the TRT and if the "progress curve" changes noticeably for you. What I...
  6. A

    Advice! Have to Use Neomycin Polymyxin Ear Drops

    ...and the effect it has had on my life. Im not simply being paranoid. You could use the same rationale approach to justify the the use of neomycin drops in ears even despite having tubes or perforated ear drums. These were the go to standard for otitis external for many many year and given to...
  7. E

    Is Anyone Else's Tinnitus All Over Their Head and Scalp?

    I was on the 10 mg pain killing dose on amitryptilyne for 12 years and got T . I have other reasons as well but will never really know the true cause. I regret the day I ever started taking it just incase it was a factor. Drs and dentists ruined my health
  8. Greg Sacramento

    New Tinnitus Sound After CT with Contrast

    @valeri 1. Have you taken any antibiotics in the last 2-12 weeks? (erythromycin, polymyxin B, neomycin and vancomycin), chemotherapeutic agent, diuretics (furosemide, bumetanide and ethacrynic acid), antimalarial drug (Quinine), anti depressant drugs and NSAIDs (Aspirin) generates or worsen...
  9. Tommi_boi

    Betnesol and Betnesol-N

    ...tell is a different product? My box just says Betnesol not Betnesol-N - Are these two things different?! Not taking this stuff if it has Neomycin. Any help would be really appreciated. Tom This is the link to what I've got -...
  10. Kriszti

    Tinnitus-Safe Antibiotic Cream for Folliculitis That Isn't Ototoxic?

    Neither of them is supposed to be ototoxic. It's a guessing game, unfortunately. Applying anything topically carries a much lower risk than per os or IV. Even on leaflets of ointments containing neomycin, the warning is just about toxicity if it goes through your eardrum.
  11. Markku

    Antibiotics for People Who Have Had Joint Replacements

    ...3 – Antibiotics – Aminoglycosides, Erythromycin, Vancomycin a. Aminoglycosides – Streptomycin, Kanamycin, Neomycin, Gantamycin, Tobramysin, Amikacin, Netilmicin. These medications are ototoxic when used intravenously in serious life-threatening situations. The blood levels of these...
  12. FloralDawn

    Diclofenac Is the Devil: DO NOT Take It If You Have Tinnitus or Hyperacusis

    Thank you so much for the helpful reply! I'm going to try a small amount of it like you did and see how it goes. Did you use gel or cream (or maybe some other topical)? I think the gel might be safer but I'm not sure.
  13. S

    Steroids: Prednisone / Dexamethasone / Others (Oral and Intratympanic Injections)

    Hi everyone - first post. I developed tinnitus and hyperacusis, 11 days ago. This was after taking Neomycin for 5 days (and immediately stopping it once I noticed the ringing). That will be the last time I ever take a drug prescribed to me without first doing research, but the damage is...
  14. grotulon

    Went to GP Today, Got Otomize Ear Spray

    Ask your doctor why he thinks giving you ototoxic ear spray is a good idea :)
  15. Zimichael

    Drug-Induced Tinnitus? How Is It Now?

    ...You can read all you need on my "Profile" info tab. Just click Zimichael, etc., etc. And yeah, the damage had already been done with the Neomycin before the Ampho. added the an extra kicker. I also personally know, and have known, others who have got T from meds (aminoglycosides in particular...
  16. ampumpkin

    Loosing It!

    ...50 pounds? On your avatar, you seem so slim... Did you have an hearing test done at the beginning? what were the results of that? I believe neomycin is the worst ototoxic antibiotics outhere! I took a -mycin antibiotics that is supposed to be ototoxic when given intraveinously... I haven't...
  17. C

    New to Tinnitus Caused by Neomycin/Polymyxin B/Hydrocortisone Ear Drops — Seeking Support

    ...discharge. I thought Id be given some eardrops and would resolve the itch. Well the specialist gave me an ear spray called Otomize (contains Neomycin). Almost immediately I began getting tinnitus. It gradually got worse over4 days at which point I stopped taking and also did my research. Like...
  18. ajc

    Having Tinnitus After Ear Wax Cleaning (Water Irrigation) and Neomycin Ear Drops

    Hello, welcome! Both of those things can cause tinnitus. I wouldn't necessarily blame the Azelastine for the ringing merging to your other ear as well. It's common for tinnitus to merge into both ears even if it appeared to start only in one. But just in case I would stop the spray myself...
  19. Kriszti

    How Do You Cope with Health Anxiety and Getting Back to Normal Living After Getting Tinnitus?

    ...shadowboxing now, and water under the bridge, but I'm so mad. I used Pimafucort on my hands due to exzema, and surprise! it contains neomycin. Which I knew, I read the leaflet, because my grandma had antibiotic resistant HAI, so I researched the big offender antibiotics. What I didn't know...
  20. paganismos

    Help, Tinnitus After Ear Irrigation, Should I Ask for Prednisone?

    ...pitch is not high anymore and its changed to a buzzing sound (after the prednisone) which is more tolerable for me. The ear drops contain neomycin sufalte, dexamethasone, polimixin b and hydroxypropyl methylcellulose. I know neomycin is ototoxic, but there's no perforation in my ear drum...
  21. jeff W

    Frequency Therapeutics — Hearing Loss Regeneration

    They will target drug induced vestibulotoxicity/ototoxicity specifically eventually I believe, it presents a perfect model as animal protocols show specific cell damage with huge amount of repeatable models already published. The litigation/claims are absolute enormous for that type of medical...
  22. Earing

    Frequency Therapeutics — Hearing Loss Regeneration

    I was thinking what if it restores some frequencies and not others so the sounds are all weird. Like when you mess with an equalizer on a stereo and the music sounds terrible. Or what if some cells start to regrow and die, and tinnitus becomes 100 times louder. The possibilities are endless.
  23. StephanieLC

    Confused About Ringing in Both Ears

    ...people developing tinnitus from a perforation only have it in the affected ear. Very confusing! I've also been worried because I had used Neomycin ear drops one time only (then realized they were ototoxic and stopped using them). I have no hearing loss in either ear and 3 ENTs are sure the...
  24. PolishSoldier87

    Celastrol Enhances Atoh1 Expression in Inner Ear Stem Cells and Promotes Their Differentiation

    ...the flat cochlear epithelium to forced expression of Atoh1. "We determined that seven days after unilateral elimination of hair cells with neomycin, differentiated supporting cells are absent, replaced by a flat epithelium. Nerve processes were also missing from the auditory epithelium. (...)...
  25. Wrfortiscue

    Tinnitus Worse After 20 Years — Doesn't Let Me Sleep and Causes Anxiety

    Jesus, what do you do for meds? My tinnitus is up and down with spikes. I don’t even know how to gauge it lol. It wakes me up everyday at night. Sometimes the spikes are loud when I wake up, other times it’s not so bad. Lately during the day it has been getting more and more quiet with fewer...
  26. J

    Just Got Diagnosed with Tinnitus

    ...and just got back from urgent care and they removed a pretty big piece of wax from my right ear. My doctor provided me with some ear drops Neomycin and Polymxxin B Sulfates... i still hear the ringing...and its driving me crazy. What is the likely hood of this going away over night? I would...
  27. Aaron123

    Inner Ear Hair Cell Regeneration — Maybe We Can Know More

    ...is a major cause of deafness. We found that HCs regenerated spontaneously in the newborn mouse after diphtheria toxin (DT)-induced, but not neomycin-induced, HC death. Regeneration depended on activation of Wnt signaling, and regeneration in DT-treated ears correlated to a higher level of Wnt...
  28. Nek

    Tinnitus After Ear Wax Being Impacted in Addition to Middle Ear Inflammation

    ...some inflammation in the canal but not on the eardrum. Told me it would go away in a few days or so but still has not. Doc. prescribed me neomycin and polymyxin but it still persisted after the 10 days I'm suppose to take it. My tinnitus sounds very high pitched, not static but like a hissing...
  29. B

    Don't Know What to Think

    ...causes, I've seen a general practitioner who spent about 5 minutes on me before sending me home with antibotics (oral azithromycin and neomycin eardrops). I realized about halfway through treatment that they probably weren't going to work, and admittedly ended up lowering the dose on the...
  30. gary

    Sudden Onset Tinnitus in One Ear

    12, it is true certain meds can cause T, but there are literary thousands of meds that have T as a side affect. I would not want to see you get a bad ear infection. Why don't you pose this question to Dr. Nagler over on "The Doctors Conner" He is an ENT & has severe T.
  31. dboy

    Is Anyone Else's Tinnitus All Over Their Head and Scalp?

    ...to each patient I would tend to believe that hearing loss is massively under-reported as a side effect. I've thought about this a lot since neomycin eardrops caused me a big increase in tinnitus, yet doctors seem to think they are safe so long as the eardrum is intact (despite knowing that...
  32. Jaysterk

    Tinnitus Spikes from Opening Soda Cans?

    ...spikes/damage from opening soda cans or any type of carbonated drink cans for that matter. Ever since I got tinnitus and hyperacusis from Neomycin 2 years ago, I've opened all my cans with earmuffs on. Particularly because I assumed that this might cause a potential setback. Two days ago, I...
  33. B

    Sudden Increase in Tinnitus; I'm Losing My Mind

    Does your ENT have an otoscope? I'm no doctor, but I thought ear drops were for inflammation of the ear canal (outer) or ear drum (that covers the entrance to the middle). Plus it seems like you'd have some visible signs of inflammation or at least minor pain if it was the outer ear and maybe a...
  34. sgal

    Antibiotic Ear Drops — Safe?

    Are there any antibiotic ear drops that are safe? My GP prescribed neomycin, polymyxin and hydrocortisone drops for my ear that had an earache in it a few days ago. On day 3, tinnitus started. I'm really afraid to take them (drops). She said my eardrum looked normal. She removed some wax...
  35. FGG

    Sound Pharmaceuticals (SPI-5557 & SPI-1005)

    I believe this paper is referring to loudness hyperacusis and not noxacusis. But I have talked to someone who had noxacusis after oral Neomycin so I'm sure it happens occasionally and I suspect would require similar treatments (though Aminoglycosides destroy way more hair cells and even...
  36. Bill Bauer

    Please, I Need Help and Encouragement. Can't See Any Hope and Don't Know What to Do.

    I also have multiple possible causes for my T. Will will never know the true culprit... The first 2-3 months after onset are the hardest. I've been there myself - I would weep multiple times a day, every day... It ought to get better, but you will need to give it time.
  37. Cameron C

    New Noise Due to Ear Infection After Months with Tinnitus. Chances It Will Be Permanent?

    Ok good, do you know how long you had it before getting treated? Im just afraid I got to it too late, since I never realized when it first started for me. I just know mine happened sometime in the months of Jan. or Feb. But knowing ya'll recovered makes me hopeful regardless.
  38. R

    Can Ototoxic Drugs Linger in the Ear?

    I was prescribed Neomycin and polymyxin b sulfates and hydrocortisone otic suspension 3 years ago and have had Tinnitus ever since, only recently has become more than annoying. I now hear it over noise and over conversations. I'm angry at the pharmaceutical company that doesn't place a big fat...
  39. Racehorse

    Hello Everyone

    ...called ‘neosporin’ for this. It’s a bacterial cream sold over the counter that contains one of the nastiest ototoxic chemicals around - neomycin-, and I was using this product in my nose so alleviate nose bleeds. Not realizing how dangerous this stuff is when used on membranes (high...
  40. Agrajag364

    Manual Earwax Removal in Ireland?

    ...advice anyone gives might have risks as well as benefits. I did end up putting a mild acetic acid-based spray on the inside of my ear as an alternative to the neomycin based drops I had been prescribed for a mild outer ear infection. But omitting to use antibiotic based drops would also have...
  41. Andrew01

    Tinnitus + Hyperacusis from Neomycin

    ...all of it so hang in there. Good luck with the elemental diet! I am going to try 2 weeks of Rifaximin to start, but willing to stop if it makes my tinnitus worse. I wouldn’t touch Neomycin with a ten foot pole but understand that Rifaximin is supposed to stay in the GI tract and is much safer.
  42. Darkener

    Ear Infection — Is Treatment a Bad Idea?

    ...and then drying up during the day. Very red and sore. So I was given Otomize ear spray, which includes 3 active ingredients: Dexamethasone Neomycin sulfate Acetic acid I'm wondering, though, if it's actually a good idea. I was told to use 3 times a day. I have used it twice so far and am...
  43. Bill Bauer

    New to This...

    Check out https://www.ehealthme.com/ds/Hydrocortisone/tinnitus/ This seems to imply that the risk is small. Going back to 1998, only 37 people had reported getting T as a side effect of hydrocortisone to the FDA. You may want to search the other components on this forum (and on the...
  44. Gb3

    Cochlear Organoids to Identify Drugs to Regenerate Hair Cells

    ...potent small molecule for hair cell differentiation. Regorafenib also promotes reprogramming and maturation of hair cells in both normal and neomycin-damaged cochlear explants. Mechanistically, inhibition of VEGFR suppresses TGFB1 expression via the MEK pathway and TGFB1 downregulation...
  45. watashiwawatashi

    Tinnitus After Ear Infection — Now Clicking and Strange Soreness in My Ears

    ...my first doctor, which looked in my ears and pretty much immediately deduced that I had an ear infection, fair enough. She gave me ear drops—Neomycin, if my memory serves me right—and sent me on my way for 2 weeks. Now, the Neomycin got rid of that pulsating, and with it, most of the pain...
  46. StephanieLC

    Steroid Medication for New Tinnitus?

    ...new tinnitus. Has anyone done this and can say it worked? I'm worried because I have a traumatic eardrum perforation, was stupidly given Neomycin/Polymyxin ear drops in the ER which I used once (3 drops) before I read they shouldn't be used with a perforation.. and a day later developed...
  47. SleeplessSoul

    Tympanometry Damaged Good Ear?

    ...it would harm me. I wish I hadn't gotten the test but I had to since I had a minor outer ear canal irritation the week before and put the Neomycin drops in for a few days and then stopped because the tinnitus spiked in my bad ear. Now here it is 3 am and I am so panicked that now my one...
  48. quietatnight

    Tinnitus from Ear Wax Removal

    Dynne I have no idea why your doctor gave you "neomycin" ? it sure was not necessary, and I don't know if it's otoxic or not, but even if it was, it's very unlikely that one dose should not cause any permanent damage, most otoxic drugs work their way out of the system over time and the...
  49. B

    Azithromycin and Tinnitus?

    I am experiencing an increase in tinnitus after 4 days (3x/d) of Neo-Poly-Dex eye drops (neomycin, dexamethasone) for chalazion. Was operating under view that eye drops do not have systemic impact and had to worry about impact on tinnitus only where AB drugs taken by oral or injection route...
  50. JohnAdams

    Celastrol Enhances Atoh1 Expression in Inner Ear Stem Cells and Promotes Their Differentiation

    Also remember this is direct application of these drugs, not oral systemic application.
  51. D

    Tinnitus Caused by Neomycin Ear Drops

    ...microsuction to remove it, and showed it to me. It looked disgusting, a glue-like consistency. He was very confident that it's the original Neomycin (Otocomb Otic) drops. He told me that I don't have to see him anymore, and my tinnitus will go away in a couple of weeks. I also had an...
  52. GregCA

    Advice! Have to Use Neomycin Polymyxin Ear Drops

    I'd personally not worry too much about it unless you have a perforated ear drum (then the drops can make their way to the middle ear and the inner ear/cochlea). But still, if you have a choice of another effective antibiotic, then perhaps a different choice would make you feel safer. How do...
  53. hopingtoheal

    New to Tinnitus Caused by Neomycin/Polymyxin B/Hydrocortisone Ear Drops — Seeking Support

    Thanks for this GregCA! Really appreciate your thoughts here. You're right—thanks for clarifying. This is encouraging to hear. I'm hopeful that the tinnitus is caused by some Eustachian tube dysfunction and, as that dysfunction is resolved, will also diminish in time. Great point. I've gotten...
  54. fishbone

    Hello Everyone

    Welcome to this site. Lots of good people here!
  55. Darkener

    Ear Infection — Is Treatment a Bad Idea?

    ...week since the infection, it's making itself known. Might be a permanent change. Very upsetting. Still reluctant to use any more spray. Neomycin is a type of antibiotic but the acidic environment created by the spray could be potentially damaging? I'm probably over worrying but my T is...
  56. Kriszti

    Diclofenac Is the Devil: DO NOT Take It If You Have Tinnitus or Hyperacusis

    ...absolutely okay. Keep in mind that my tinnitus is most probably not from ototoxic drugs. There is a slight chance, because I used topical Neomycin 4 days before original onset, but noise damage is much more likely. Original poster got spike from Diclofenac pills. I think in gel form, it's...
  57. JaysterT

    Worsening Tinnitus — Could It Be Because of a Recent Course of Antibiotics (Doxycycline)?

    I am no expert but I have seen Pregabalin thrown around here as causing tinnitus. I myself took it for about a month or so and didn't notice anything BUT shortly after I took Neomycin and baam I now have tinnitus and hyperacusis. STAY FAR AWAY FROM ANYTHING ENDING IN "CIN".
  58. FGG

    Terrible Tinnitus; Suspecting Ototoxicity from Polydexa (Neomycin and Polymyxin B)

    Anytime ototoxicity is suspected, I would consider steroids as soon as possible to mitigate as much of the damage as you can. It may be too late for oral steroids but intratympanic may still be possible. See an Otologist asap, and try to get an extended audiogram because ototoxicity shows up...