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  1. O

    Jumping/Jogging Changes the Pitch: A Sign of Somatic Tinnitus?

    I have the same type of tinnitus. Chronic ringing but also a pulsating high-pitched tinnitus. It also is in sync with my heartbeat when I run etc, and if I yawn, I get a louder separate tinnitus sound. Mine was caused by gunshots but worsened by Bruxism. This is somatosensory tinnitus but I...
  2. O

    Blocking Notch Pathway Leads to New Route to Hair Cell Regeneration to Restore Hearing

    I do. Barring a major discovery in molecular therapeutics (which isn’t completely impossible), I think we are at least two decades out from any sort of hearing regeneration therapeutics being available to the general public. Maybe longer for gene therapy. Gene therapy will probably also be...
  3. O

    Blocking Notch Pathway Leads to New Route to Hair Cell Regeneration to Restore Hearing

    Gene therapy though. Still many decades away. Molecular therapy is closer, just need to find the right molecule for the MYC pathway.
  4. O

    Dysacusis (Hearing Distortion) etc.

    A little update. I still have the distortion and it fluctuates from day to day. I have not tried benzos to see if they help with minimizing it. Flexing my masseter muscle also causes a high frequency chirp in my right ear. I suspect somatic tinnitus in addition to the dysacusis. I really wish...
  5. O

    New University of Michigan Tinnitus Discovery — Signal Timing

    Mine is worse after I am exposed to loud sound. I think it might be related to endocochlear hydrops or cochlear nerve inflammation in response to sound. It seems to be better when the tinnitus isn't as bad. I don't foresee Dr. Shore's device helping with the seashell but it should help with the...
  6. O

    What Do You Drink? What Beverages Can Improve or Worsen Tinnitus?

    Red wine, sour beers, Erdinger weissbier... water... basically whatever whenever but I try to limit alcohol to keep testosterone production up!
  7. O

    such an annoyance man; before this I loved life, I mean I still love life but it isnt as fun...

    such an annoyance man; before this I loved life, I mean I still love life but it isnt as fun when you are constantly suffering. lots of ppl are exposed to noise and dont develop it; we just got unlucky. A positive attitude makes a big difference, the symptoms worsen with stress and depression
  8. O

    I live in Canada so it could be many years before I get a chance at SS device. I am also willing...

    I live in Canada so it could be many years before I get a chance at SS device. I am also willing to try psilocybin therapy and other , as it seems that it gets worse as time goes on.
  9. O

    i was 22,hunting with my brother and didnt wear plugs, I brought them and when i went to put...

    i was 22,hunting with my brother and didnt wear plugs, I brought them and when i went to put them in he rushed me and told me to put them in after one bird. well, we got it and i forgot to put them in after my ears were never the same after.
  10. O

    Gunshot-Induced Tinnitus and Minimal Hearing Loss — Any Guidance Appreciated

    You can still shoot, but I would recommend investing in a suppressor system and not shooting without doubling up. Maybe it is best to reduce your shooting and look at other quieter hobbies to give your ears a chance to heal over the next year or two. Eat well, exercise and make sure you aren't...
  11. O

    New University of Michigan Tinnitus Discovery — Signal Timing

    I have two or three tinnitus tones. One can be manipulated with jaw movements and the other two are static. One is a tone, the other is a seashell like sound. @generalfuzz's ACRN helps with all of the tones except for the seashell sound. Do you think Dr. Shore's device could help me?
  12. O

    New University of Michigan Tinnitus Discovery — Signal Timing

    I have subjective tinnitus caused by an acoustic trauma (17 years ago) and it has worsened in the last years because of new noise exposures, TMJ and Bruxism. I now have worsened chronic ringing and “hissing” that is in sync with my pulse and can be silenced with mandible protrusions and flexion...
  13. O

    New University of Michigan Tinnitus Discovery — Signal Timing

    Guys, everyone really needs to leave Dr. Shore alone and let her work in peace. Some members of this community have an awful habit of pestering (some would call harassing) companies and scientists about treatments, and turning on them when there is nothing there for the individual emailing; it...
  14. O

    Otonomy OTO-413 — Treatment of Hidden Hearing Loss

    Otonomy is liquidating all assets and paying stockholders any remaining revenue. Keep or dump stock?
  15. O

    Repeated Modified Nerve Blocks and Auditory and Non-Auditory Nerve Stimulation

    Bro, it might work for those with skeletomuscular origins of tinnitus or cervical instability. Noise induced tinnitus might be different. I’m sorry it didn’t work for you. Meditate, focus on good healthy living and distracting yourself by staying busy. Try acupuncture, massage therapy, wait for...
  16. O

    New University of Michigan Tinnitus Discovery — Signal Timing

    there is a subset of somatic tinnitus called somatosensory pulsatile tinnitus whereby the DCN no longer cancels somatosensory sounds hence modulation of sounds through muscle or joint movements. The other theory is that the auditory pathway/brain taps into existing somatic pathways to maintain...
  17. O

    Hey, how are you doing now? I have similar symptoms I know what you are going through

    Hey, how are you doing now? I have similar symptoms I know what you are going through
  18. O

    New University of Michigan Tinnitus Discovery — Signal Timing

    Will Susan Shore’s device assist with reactive tinnitus? Or somatosensory pulsatile tinnitus?
  19. O

    Alterations in Auditory Brain Stem Response Distinguish Occasional and Constant Tinnitus

    Me too. I guess that is how the brain is supposed to work...
  20. O

    Hough Ear Institute's Hair Cell Regeneration Project

    Is anyone going to go to record what he has to say?
  21. O

    Sound Pharmaceuticals (SPI-5557 & SPI-1005)

    Otonomy already tried a steroidal treatment for Meniere's and it failed miserably.
  22. O

    New University of Michigan Tinnitus Discovery — Signal Timing

    4 to 6 thousand? So it will be unaffordable for 90% of the population? Bad business strategy.
  23. O

    Repeated Modified Nerve Blocks and Auditory and Non-Auditory Nerve Stimulation

    No control group... I have seen this many times before and it always turns out to be a dud. Yes, multiple types of tinnitus or multiple causes, but here we are and there isn't a true treatment for any of them, let alone a cure.
  24. O

    Repeated Modified Nerve Blocks and Auditory and Non-Auditory Nerve Stimulation

    No full cure of tinnitus, very mixed results, lots of guys doing it with little or no result. Just based on what I’m reading it doesn’t seem like there’s much validity in it.
  25. O

    Repeated Modified Nerve Blocks and Auditory and Non-Auditory Nerve Stimulation

    A lot of this seems like placebo, these results don’t scream curative. This is unfortunate.
  26. O

    Otonomy OTO-413 — Treatment of Hidden Hearing Loss

    OTO-413 has had better results than OTO-313 so far. The synapses readily respond to the medication and reconnect to the hair cell terminals. Easier to measure success too.
  27. O

    Frequency Therapeutics — Hearing Loss Regeneration

    Usable voice frequency band is 300 Hz - 3400 Hz. If word recognition is improved, then I would imagine tinnitus may benefit from these spectrums. Can’t see how 10,000 Hz would benefit other than it being exposed to the medication first. Most of speech energy is produced in the low-mid range of...
  28. O

    New University of Michigan Tinnitus Discovery — Signal Timing

    Fingers crossed this trial is successful and helps to quieten the sounds...
  29. O

    Neurosoft Bioelectronics: Implantable Electrodes to Treat Tinnitus

    Dr. Dirk De Ridder also said that hearing aids don't help with tinnitus but we know that in a lot of people both cochlear implants and hearing aids silence it for some people. Hell, I can turn on some neuromodulation videos on YouTube and get silence for a few minutes. I take what that guy...
  30. O

    Hough Ear Institute's Hair Cell Regeneration Project

    What is Hough Ear Institute doing these days? Whatever became of their bomb blast pill?
  31. O

    Tinnitus Seems to Be Somehow Linked to a Crucial Bodily Function, Studies Hint

    I too do not experience tinnitus when I sleep. But I also don’t experience smells, sounds or consciousness lol.
  32. O

    Prof. Thanos Tzounopoulos Receives $2 Million Grant

    Dude I understand you're suffering, like many, but that email you sent him comes off as rude and passive-aggressive and really does nothing to help the cause of the community. If anything it would push him away from interacting with sufferers.
  33. O

    Somatic Tinnitus and Treatment ⁠— New Evidence

    With regards to the chirp with masseter flexing... a high pitched "chirp" not far off from the hissing. Interestingly, when wearing my bite plate, my left masseter when flexed will also evoke an extremely similar "chirp". When I remove the bite plate the left masseter will not chirp upon flexion...
  34. O

    Lineage Cell Therapeutics — ANP1 for Treatment of Auditory Neuropathy

    I don't understand any of this. Seems like a funding drive for another failed biotech.
  35. O

    NeuroVR Device: Neurofeedback to Treat Tinnitus

    VSS has been cured or reduced with VR in some cases.
  36. O

    Somatic Tinnitus and Treatment ⁠— New Evidence

    Greg, based on your post earlier about people having tinnitus from noise trauma developing somatosensory tinnitus later, do you think it’s possible for this somatosensory tinnitus to be treated or reduced via TMJ/cervical treatment? I have to continue to strengthen my neck or it gets really...
  37. O

    Somatic Tinnitus and Treatment ⁠— New Evidence

    Forward head posture can be cured as long as it hasn't progressed to some kind of calcified/permanent kyphosis, but even then it can still be treated to some degree. Exercise, core training and physio/posture training can all help with posture.
  38. O

    I Think I Have Somatosensory Pulsatile Tinnitus

    Bumping the somatosensory pulsatile tinnitus thread to see if any have had any successes in treatment...
  39. O

    Acoustic Trauma Induced Low Hum Almost Completely Gone by Lowering Chin to Chest

    My tinnitus is similar, I have loud tonal tinnitus in my right ear, chronic 24/7 and on top of that I have a static "hissing" in my right ear that I can modulate with my jaw, and SCM muscles. The hissing is synchronized with my heart beat and I can stop the hissing my protruding my mandible or...
  40. O

    UCI — Acoustic and Electrical Stimulation for the Treatment of Tinnitus

    Don’t need to fully understand it. Few medical conditions are fully understood. Just need real efficacious treatments, and stat.
  41. O

    Repeated Modified Nerve Blocks and Auditory and Non-Auditory Nerve Stimulation

    Sounds like it all could be natural healing that may also have happened without intervention. Only something like 2-5% of cases are chronic. Not holding my breath on this one, especially given the location of the treatment. It’s basically unattainable for North Americans.
  42. O

    Repeated Modified Nerve Blocks and Auditory and Non-Auditory Nerve Stimulation

    Why is somatosensory tinnitus an exclusion for participation in the paper?
  43. O

    New University of Michigan Tinnitus Discovery — Signal Timing

    I am a non-combat vet and I have it. I already had tinnitus but I developed the somatosensory tinnitus after a subsequent work related noise exposure. Constant hissing that I can modulate with jaw movements. I can also hear my heartbeat “hissing” in sync with it and it’s worse when exercising...
  44. O

    Repeated Modified Nerve Blocks and Auditory and Non-Auditory Nerve Stimulation

    I haven't read the paper but a part of me is thinking it could just be marketing for their private clinic. The lack of a control group/placebo is not good.
  45. O

    Repeated Modified Nerve Blocks and Auditory and Non-Auditory Nerve Stimulation

    Hoping this is legit and helps millions of us. There is most certainly a connection to the facial nerves and auditory nerves hence the somatosensory tinnitus that many of us develop in response to sound. Even if this works, I think there is still a market for Dr. Shore's device. We need all...
  46. O

    Hough Ear Institute's Hair Cell Regeneration Project

    While I hope it helps you, I believe the drug was developed to treat tinnitus and hearing loss stemming from noise causes. Best of luck.
  47. O

    tFUS (Transcranial Focused Ultrasound) for Brain Health & Possibly Helping Tinnitus

    Near the end with regards to vagus nerve stimulation.
  48. O

    Frequency Therapeutics — Hearing Loss Regeneration

    New hair cells likely are not attached to the auditory nerve.
  49. O

    Objective Measurement of Tinnitus — ABR (Auditory Brainstem Response)

    Still have no way to fix it unfortunately.
  50. O

    Frequency Therapeutics — Hearing Loss Regeneration

    This is in vivo buddy. I guess once drugs like OTO-413, FX-322 and FX-345 hit the market we will have somewhat of an idea as to whether regenerating hair cells will reverse tinnitus. Are any drugs coming to repair hair cells that have been damaged by noise but are still semi functional?
  51. O

    Otonomy OTO-413 — Treatment of Hidden Hearing Loss

    If only regenerating the cochlea were that easy friend. I actually agree with you that the brain may adapt and fix precious maladaptive tendencies.
  52. O

    Sensorion's New Drug: SENS-401

    They're still evaluating it for secondary endpoints.
  53. O

    Ideas and Suggestions for Future Episodes

    Charles Liberman, Ed Rubel, Albert Edge, Stefan Heller, Ronna Hertzano, Anthony Ricci, Matthew Fitzgerald, ... I have other suggestions. Great work with the podcast. Looking forward to future episodes. I will contribute more when financially able.
  54. O

    Sensorion's New Drug: SENS-401

    Let's hope 4 weeks was long enough for any hair cells that would regenerate to regenerate. Also we don't know; it is entirely possible that the hair cells regenerated but did not connect to the nerves. Might need a dual drug therapy that delivers the hair cell re-generator and then a cochlear...
  55. O

    Acoustic CR® Neuromodulation: Do It Yourself Guide

    Treatment Tone Spacing and Acute Effects of Acoustic Coordinated Reset Stimulation in Tinnitus Patients The more I read the more hopeful I become. There are great strides being made with regards to hearing disorders; bimodal stimulation, neuromodulation, electrical stimulation, pharmacological...
  56. O

    Otonomy OTO-413 — Treatment of Hidden Hearing Loss

    Upon further investigation, many experts in the field are theorizing that cochlear synaptopathy may in fact be responsible for some tinnitus and hyperacusis. Check out this quote from Dr. Charles Liberman. There may be a benefit of such drugs for those suffering from tinnitus or hyperacusis. In...
  57. O

    Otonomy OTO-413 — Treatment of Hidden Hearing Loss

    I don't think this is the drug we're waiting for. They said on the Tinnitus Talk Podcast that there were no reports of tinnitus improving with the usage of the drug in the trials. Maybe the drug would have an application as an adjunct therapy with Dr. Susan Shore's device or something; but...
  58. O

    Frequency Therapeutics — Hearing Loss Regeneration

    This is true and is why tinnitus is an anomaly and the vast majority of people will never experience tinnitus in their lifetime.