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Yet another team is trying to solve the inner ear delivery issue. Injectable polyplex-loaded glycol chitosan thermogel for efficient and safe inner ear gene delivery Highlights A novel RH-PAMAM G2 polyplex-loaded HGC thermogel system has been designed to enable effective gene delivery to the...

Well, it is a shame that hyperacusis sufferers were not allowed to take part in this survey. A Delphi survey to determine a definition and description of hyperacusis by clinician consensus Objective There is currently no singularly accepted definition of hyperacusis. The aim of this study was...

I am not a doctor, therefore I don't know the medical flow charts or medical guidelines. I just wonder what were the hints that tell the doctors to test an extended CT and MRI (not just in the cerebellopontine angle to rule out Vestibular Schwannoma). Is it because the patient suffered left...

Jugular Bulb Abnormalities Associated with Phlebectasia in Patients with Meniere’s Disease: Novel Surgical Approach Internal Jugular Phlebectasia (IJP) is a rare entity in which there is a fusiform dilatation of internal jugular vein, usually presenting with a neck mass or tinnitus. The Jugular...

This article mentions that paraganglioma can trigger tinnitus, although it does not mention if the resection of these tumors stops tinnitus. Transcanal endoscopic excision of tympanic paraganglioma: A three-case series Paragangliomas are rare neuroendocrine tumors that arise in sympathetic and...

This thread is aimed at gathering information about occupational noise at work (not including military and recreational). An overview of occupational noise-induced hearing loss among workers: epidemiology, pathogenesis, and preventive measures Occupational noise-induced hearing loss (ONIHL) is...

This kind of tumor (so different from Vestibular Schwannoma) can cause tinnitus. So it needs to be screened. Extensive Meningioma of the Posterior Cerebral Fossa Presenting as a Serous Otitis Media Meningiomas are benign tumors originating from the arachnoid villi of the meninges. Meningiomas...

I thought it was not useful to post this publication in the "Research News" section but also thought it was more useful to post it in this section since a lot of newbies (who are most of the time anxious) could be reassured if they fall into one of the categories described. Eventually, this...

For those interested in electronics, we can have this thread to gather all electronic models of the auditory system. First article: A Transmission-Line-Based Cochlear Standing Wave Model To Elucidate Mechanism of Human Auditory System Abstract— How do people hear sounds? As a counterpart of...

The neuro-otology of Susac syndrome Objective We characterised the clinical and neuro-otological characteristics of patients with Susac syndrome. Methods The medical records of 30 patients with Susac syndrome were reviewed for details of their clinical presentation and course, neuro-otological...

Abstract Purpose: Hyperacusis is a disorder characterized by reduced sound tolerance leading to ear pain, emotional distress, and reduced quality of life. Many people with hyperacusis turn to the Internet for information and support from online communities to discuss their condition. The...

Pulsatile tinnitus caused by an aberrant artery running over the surface of mastoid bone Objective Pulsatile tinnitus (PT) caused by an aberrant artery is rare. We report an unprecedented cause of PT resulting from an aberrant artery coursing the mastoid surface, and qualitatively discuss the...

‘Sound Cannons’ Used on Protestors Can Cause Serious Hearing Loss or Damage Long Range Acoustic Devices (LRADs)—also called sound cannons—emit high-decibel sounds up to 162 dB SPL. That level is well above unsafe noise exposure for any amount of time and can cause permanent hearing loss...

Even if it is a case study, it seems interesting: Pulsatile tinnitus caused by pneumocephalus after Janneta surgery Pulsatile tinnitus of nonvascular origin is rare. We herein present a case of pulsatile tinnitus complicated with Jannetta surgery due to a communication created between the...

Tinnitus associated to middle ear surgery and correlation to the audiometric data. Aim: To evaluate the effect of middle ear surgery on Tinnitus and possible correlation to the audiometric data. Materials and methods: Retrospective analysis of all middle ear surgeries in a tertiary university...

I wanted to start a thread in the research news section for those who are concerned. First article below: Comparison of translabyrinthine and retrosigmoid approach for treating vestibular schwannoma: A meta-analysis Highlights To roughly evaluate the efficacy and safety between...

Seyit Mehmet Ceylan Department of Otolaryngology, Sanko University School of Medicine, Gaziantep, Turkey BACKGROUND/AIMS This study aimed to identify and analyze the top 100 cited articles about tinnitus research. MATERIAL and METHODS Using the Web of Science database, we searched the term...

Association of periodic limb movements during sleep and tinnitus in humans Abstract Both of periodic limb movements during sleep (PLMS) and tinnitus were related with dopaminergic system dysfunction. However, it was still unclear whether PLMS, one kind of sleep disturbances, was associated with...

1 - Cause of tinnitus is not mentioned. 2 - Henk koning performed percutaneous radiofrequency of C2 in a previous study: Percutaneous Radiofrequency Lesion of the Superior Cervical Sympathetic Ganglion and Tinnitus. ABSTRACT Introduction: The eight cervical nerve might be a source of input to...

Assessing the Heterogeneity of Complaints Related to Tinnitus and Hyperacusis from an Unsupervised Machine Learning Approach: An Exploratory Study Abstract Introduction: Subjective tinnitus (ST) and hyperacusis (HA) are common auditory symptoms that may become incapacitating in a subgroup of...

Superior semicircular canal dehiscence (SSCD) is a rare disorder that causes vestibular and auditory symptoms resulting from a dehiscence in the middle cranial fossa floor overlying the superior semicircular canal (SSC). The symptoms that result from this include vertigo, autophony, hearing...

I am confused since it also talks about non pulsatile tinnitus. Background: There is no consensus on the prevalence of sigmoid sinus dehiscence, with each study offering various definitions and mechanisms of symptoms. Patients who undergo resurfacing surgery for sigmoid sinus dehiscence do so...

Objective: This study aims to evaluate the clinical characteristics and present surgical outcomes of transtemporal venous decompression technique in the treatment of pulsatile tinnitus. Study Design: Prospective cohort study. Setting: Tertiary private neurotologic skull base clinic. Patients...

Background: The Human Immunodeficiency Virus (HIV) has become a global pandemic. With the improvement of antiretroviral (ARV) treatment regimens, life-expectancy of HIV-positive individuals has increased. HIV literature suggests that head and neck manifestations may be the first indication of...

Tinnitus is not mentioned in the Abstract but is mentioned in the full article. Full article: https://academic.oup.com/milmed/advance-article/doi/10.1093/milmed/usz471/5721123 Gulf War Illness Symptom Severity and Onset: A Cross-Sectional Survey Abstract Introduction: Gulf War illness (GWI)...

I did not know in which thread to put this "UFO" info, so I created one. I hope I gave it a good title. If I understood correctly, we use artificial intelligence to predict whether this or that treatment (rather psychologically oriented) will be effective on this or that person. Honestly, I...

A recent consumer survey by Deloitte reported that smartphone adoption rates are nearing their peak, with as close to nine in 10 adults (aged 18-75 years) having a smartphone that can support mobile applications (apps).1 Ninety-five percent of smartphone owners use their device every day, and...

An Investigation of Hearing (250–20,000 Hz) in Children with Endocrine Diseases and Evaluation of Tinnitus and Vertigo Symptoms Abstract Introduction: Despite much advancement in medicine, endocrine and metabolic diseases remain an important cause of morbidity and even mortality in children...

P1495 Suddenly haunted by a turbulent heart beat in the right ear. Post-traumatic monolateral pulsatile tinnitus caused by cervical arteriovenous malformation: colour-Doppler ultrasound and angio-CT find INTRODUCTION Tinnitus, the perceived sensation of sound in absence of corresponding...

MRI detection of endolymphatic hydrops in Meniere's disease in 8 minutes using m3D-real IR and a 20-channel coil after targeted gadolinium delivery Abstract Background Endolymphatic hydrops (EH) become visible in vertigo patients, particularly in those with Meniere's disease (MD), in vivo using...

Development and Validation of Hyperacusis Handicap Questionnaire in Individuals with Tinnitus Associated with Hyperacusis ABSTRACT Introduction: Hypersensitivity to sound and tinnitus are often co-morbid and can influence emotional well-being, hearing, sleep, concentration, cause anxiety, and...

For those who are interested in the correlation between viruses and tinnitus. BACKGROUND/AIMS Tinnitus is a common medical problem that disrupts patient comfort. The majority of the reasons accused in the etiology of tinnitus are unknown. The aim of the present study was to determine the...

Abstract Hypothesis: We hypothesize patient-specific flow models to be an adequate in vitro surrogate to allow for characterization of pulsatile tinnitus (PT) that affects three to five million Americans. Background: PT, rhythmic sounds without an extracorporeal source that patients...

Psychosocial consequences of the loudness of tinnitus Introduction: Tinnitus distress is associated with the perceived loudness of the tinnitus. Objectives: To evaluate the psychosocial problems in tinnitus patients and to explore any relation with the tinnitus loudness.Design: From all...

Abstract Previous studies have shown that personality traits are related to tinnitus distress as measured by the Tinnitus Handicap Inventory (THI) and the Tinnitus Questionnaire (TQ). However, little is known about the role of personality on tinnitus distress over time. We collected the THI and...

For those who are interested in statistics, see attached file. Hearing Difficulties and Tinnitus in Construction, Agricultural, Music, and Finance Industries: Contributions of Demographic, Health, and Lifestyle Factors

Do they want to make THI and THQ obsolete? An Exploratory Step Toward Measuring the 'Meaning of Life' in Patients with Tinnitus and in Cochlear Implant Users. Abstract BACKGROUND: Many questionnaires attempt to quantify the "quality of life." However, we believe understanding the quality of...

Shame on me! I realized with the interview of Professor Alain Londero at the TRI 2019 conference: That I forgot to relay this piece of news: https://clinicaltrials.gov/ct2/show/NCT03773926 https://medtechengine.com/article/tinnitus-solved-the-french-start-up-that-wants-to-end-the-torment/...

Abstract In October 2018 the new Environmental Noise Guidelines for the European Region were published by the World Health Organization (WHO), providing strong evidence that noise is one of the top environmental hazards to both physical and mental health and well-being in Europe. However...

A Pertinent Reconstructive Surgical Method Targeting Dural Sinus Hemodynamics to Resolve Pulsatile Tinnitus Objectives: 1) To provide information on the treatment of pulsatile tinnitus (PT) with transtemporal extraluminal sigmoid sinus angioplasty (ESSA); and 2) to discuss the current clinical...

Cognitive Performance in Chronic Tinnitus Patients: A Cross-Sectional Study Using the RBANS-H. Abstract OBJECTIVE: Many tinnitus patients report cognitive deficits such as concentration and attention difficulties. The aim of this study was to comprehensively assess cognitive functioning in...

I know this is another sound therapy, but I relay this news without censorship. The Long‐term Effectiveness of Tinnitus Multivariate Integrated Sound Therapy (T‐MIST) in 148 Tinnitus Patients with Normal Hearing Thresholds: Our Initial Experience Abstract This preliminary study provides a...

What do our Indian Fellows think about it? Indian Society of Otology A Prospective Study to Evaluate Effectiveness of a Tinnitus Relief Device in a Clinical Setup Abstract Introduction Tinnitus has been shown to decrease the quality of life of a person. Being a less understood domain of the...

Study on treatment of chronic tinnitus by tetanus stimulation and evaluation methods of tinnitus. DOI: 10.13201/j.issn.1001-1781.2019.09.015 Abstract Objective: The purpose of this study was to explore the efficacy of tetanus stimulation in tinnitus treatment and the correlation between the...

Researchers Discover Proteins That Could Soon Restore Damaged Hearing and Irreversible Deafness https://www.hopkinsmedicine.org/news/newsroom/news-releases/researchers-find-proteins-that-might-restore-damaged-sound-detecting-cells-in-the-ear 08/05/2019 Using genetic tools in mice, researchers...

Since there was no thread about "otosclerosis" or "stapes surgery" in the "Research News" section, I created one. Changes in Hearing Threshold and Tinnitus Severity after Stapes Surgery: Which Is More Important to the Patient’s Quality of Life? https://doi.org/10.1159/000500992 Abstract...

Parental Separation and Parental Mental Health in Childhood and Risk of Insomnia in Adulthood among Patients with Tinnitus. Abstract BACKGROUND: Many patients seeking help for tinnitus also suffer from insomnia. Adverse childhood experiences may affect the likelihood of insomnia in later life...

Since I did not find a thread about "canal dehiscence" in the "Research News" section, I created one. For those who are concerned by canal dehiscence and tinnitus, here is an article to make up your mind before surgery. Sealing of superior semicircular canal dehiscence is associated with...

Jose Luiz Villaça Avoglio Private practice of Orthodontics, Guaratingueta, Brazil https://doi.org/10.1016/j.mehy.2019.109280 Abstract There is large support in literature linking tinnitus to dental occlusion and temporomandibular joint disorders (TMD). However, there is no model to explain such...

I did not manage to find the clinical trial registered number. A double-blind randomized controlled trial on the efficacy of mixed pure tone sound therapy in chronic tinnitus patients with different hearing loss]. Objective: The effectiveness of two different sound therapies in chronic...

I did not manage to find out if this clinical trial is related with the other "neurofeedback" threads. First the reference of the clinical trial: https://clinicaltrials.gov/ct2/show/NCT02383147 Then the results below: https://doi.org/10.1155/2019/3540898 Investigating the Efficacy of an...

Systematic Review of Temporal Bone–Resurfacing Techniques for Pulsatile Tinnitus Associated with Vascular Wall Anomalies George S. Liu, Brian C. Boursiquot, Nikolas H. Blevins, MD, ... First Published January 22, 2019 https://doi.org/10.1177/0194599818823205 Abstract Objective To...

For those who are concerned by this specific subtype of tinnitus : clocking tinnitus and migraine. Clocking tinnitus: An audiology symptom of migraine Abstract Objectives In contrast to previous concept that tinnitus is confined to an otologic disorder, current evidence supports it as a...

Imaging of Ménière https://books.google.fr/books?hl=fr&lr=&id=Z2p7DwAAQBAJ&oi=fnd&pg=PA19&dq=tinnitus&ots=RsBpkwVSDi&sig=Ii-CQBUVk1m4cqH8Nd4gvkTIhww#v=onepage&q=tinnitus&f=false Key Points The delayed (4-hour) intravenous gadolinium-enhanced 3D FLAIR MR imaging technique is most frequently...

I admit that I appreciate the efforts made by Iranian researchers on tinnitus: they are very pragmatic, very focused on experiences, and cross all aspects of this condition. Even if it is not always conclusive, it has the merit of being done. Effect of Low-Level Laser Therapy on Otalgic Pain...

https://www.msn.com/en-us/travel/video/a-swiss-tourist-sues-graceland-hotel-for-dollar75000/vi-BBOWSX8 A Swiss tourist claims the hotel located across the street from Graceland failed to turn off an emergency alarm for 30 minutes, which ultimately caused him to develop the condition tinnitus...

For those who are interested and concerned by Acoustic Neuroma.

Stapes hypermobility as a possible cause of hyperacusis Abstract Objective Hyperacusis is a reduction of normal tolerances for everyday sounds. Although several publications have been produced demonstrating that minimally invasive surgical procedures may improve patient symptoms, the precise...

Sound Change Integration Error: An Explanatory Model of Tinnitus A growing body of research is focused on identifying and understanding the neurophysiological mechanisms that underlie tinnitus. Unfortunately, however, most current models cannot adequately explain the majority of tinnitus...