Search results for query: *

Introduction: During the last decade, a number of candidate drugs for the treatment of tinnitus have emerged with the hope of alleviating the burden of millions of sufferers with a persisting ringing in their ears. Knowledge of the pathophysiologic mechanisms has progressed remarkably in the...

Otonomy posted their 1st quarter financial results today. I think most of the stuff in there is already known, however, it gives a nice short summary about their drug pipeline...

Only slightly interesting despite the title: Apawu AK, Curley SM, Dixon AR, Hali M, Sinan M, Braun RD, Castracane J, Cacace AT, Bergkvist M, Holt AG. MRI Compatible MS2 Nanoparticles Designed to Cross the Blood-Brain-Barrier: Providing a Path towards Tinnitus Treatment. Abstract: Basically...

Didn't see that coming... This might be of interest for people taking part in the AM-101 (or similar) trial or having intratympanic steroid injections: Using anaesthetics doesn't help reduce the pain of the injection

https://www.boehringer-ingelheim.com/press-release/china-southeast-university-collaboration-develop-hearing-loss-treatments They started working with Kyoto University on this topic earlier this year...

Well, sometimes you stumble upon strange things. This is definitely one of 'em... ;) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803736/ Basically they are currently trying to help people with cervical pain syndrome using cervical collars. A larger paper is in preparation. The article reports...

Action on Hearing loss funds research on stem cell delivery.

See their NEWS page entry from September 1st (unfortunately there's no direct link to the article, only to the news page). PRAGMA Therapeutics and UK Ministry of Defence’s Center for Defence Enterprise collaborate to support preclinical research on innovative treatment for tinnitus September...

Wow, didn't expect this: I haven't read the full study yet, but if anyone's interested, it's available online.

https://www.statnews.com/2016/07/13/hearing-loss-decibel-steven-holtzman

Seems like it's almost there... Press Release

More interesting basic research on how hair cell regeneration works. Action on hearing loss has a nice article summarising the result. Or take a look at the journal article. Short summary: Birds do it, fishes also (where "it" means regenerate hair cells, of course...). So they looked at what...

Seems like they're trying to find other uses for the drug. Reading this it seems like the CLARITY-1 trial is doing better than their QUIT-1 trial (of course this is just speculation)... Autifony Press release

Somewhat off-topic, but I just stumbled over an interesting article in Scientific American about chronic pain. While it's not about tinnitus, it might still be an interesting read for those interested in the broader context, as the mechanisms in play are somewhat similar. The basic mechanisms...

Not sure why no one found this yet, but Autifony posted a summary of the QUIET-1 study: http://www.autifonytherapeutics.com/publications/Autifony_QUIET_Final_data_FINAL_28April2016.pdf Summary: There was basically no difference between the placebo and AUT00063 group. Highlights: - AUT00063...

Has someone here noticed any difference to their tinnitus when taking Ambroxol? It's the active ingredient of several cough medicines and seems to have pretty few side effects and is pretty cheap. Actually, it's available without prescription in Germany (and probably everywhere else). There...