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  1. patorjk

    Coffee Fruit Extract to Increase BDNF?

    We now know that OTO-413 (BDNF) can improve hearing when injected into the cochlea. It's got me wondering if supplements that increase BDNF in the body can have any kind of noticeable effect. I know there were people trying high doses of Turmeric / Curcumin, with some claiming it helped -...
  2. patorjk

    Otonomy OTO-6XX — Hair Cell Regeneration

    This thread is for discussion of OTO-6XX, a drug being developed by Otonomy to regenerate hair cells in the ear. At the time of this posting, very little is known about the drug. Here's what I'm aware of at the moment: * It's been in development for several years. * As of August 2020, Otonomy...