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Warning: long, speculative rabbit hole. I came across this study last night and was intrigued (I'm going to tie this into noxacusis, stick with me): Middle Ear Muscle Dysfunction as the Cause of Meniere's Disease It suggests that hydrops is perhaps a consequence of middle ear dysfunction in...

Somehow this trial has fallen under the radar but is interesting and the current phase wraps up end of this year: Effects of Huperzine A on Presbycusis(Δ,kHz, dB,MMSE, AD) Huperzine A is an Acetylcholinesterase (AChE) Inhibitor and it seems most relevant to age-related hearing loss sufferers...

I don't think I quite realized how confusing noxacusis terminology is until I got it myself. It's been eye opening to say the least. With tinnitus, I easily knew the brief period I had it severely was "severe" (could only be masked by a noise as loud as a hair dryer) and understand that it is...

Hi all, So I have developed ear and face pain recently and even though my case isn't severe (I can do 80% of normal daily activity with ear plugs in), I live with someone now (my reselling partner) whose long term plans are likely to take him back to the state he's from. That could happen as...

I'm writing this on behalf of someone who wants to know if others suffer from this but doesn't have the mental or emotional energy to start the thread themselves and asked me if I would. Is there anyone here who has about a dozen tinnitus tones and multiple reactive tones on top of this...

Starting a thread for anyone who is interested in following medical progress in general and not just in the otology and tinnitus space. It's definitely a transformative time for medicine where research is moving away from symptomatic treatment and addressing the underlying pathophysiology. I...

After reading this, I'm very curious if it's possible to affect potassium ion channels appreciably naturally. Going to give this a go: https://www.fasebj.org/doi/10.1096/fj.201900485R Has anyone else tried cilantro extract?

Autifony are back with a new Kv3 potassium ion channel compound. This one is for schizophrenia and "hearing disorders." I wonder what "hearing disorders" they are referring to. This was announced today: Autifony Therapeutics announces commencement of a Phase I study of AUT00201, a novel Kv3...

I had mentioned this in other threads, but I had been working on a letter to Dr. Woodcock of the FDA. Before I sent it to her, however, I was looking for member feedback. I know a few people have expressed interest in helping me with this letter. The mods suggested I put this post in this...

Came across this website and biotech company. They apparently have a drug for tinnitus and another for treating NIHL in pre-clinical. As well as a prevention for NIHL in phase 2. So far, though, I can find no other info about them apart from their website. Anyone know more...

Ultimately, whether by regenerative medicine or bimodal stimulation (once they fine tune it better especially), neuroplasticity is what will be needed to reduce or eliminate tinnitus at that point. There are lots of examples of this working conceptually; Mirror therapy for phantom limb...

Anyone have experience with this? This is unrelated to tinnitus, but it looks like my best friend (and the only person who was in the trenches with me through all my health battles) is facing this. I'm at the ER with him and he is rapidly losing the ability to walk and I'm scared shitless...

Hi y'all. I spend entirely too much time on this forum, but it troubles me that, in all my reading, i have yet to find someone with my flavor of hearing issues. Background: I had sudden bilateral and symmetrical hearing loss about 10 months ago due to high dose (and prolonged) Azithromycin...

Found this announcement today: https://www.businesswire.com/news/home/20191113005806/en/Pipeline-Therapeutics-Participate-Stifel-2019-Healthcare-Conference Here is their official website: https://www.pipelinetherapeutics.com/ It appears to be a relatively new biotech company. Of note...

Hi, Been mostly posting in the research thread but I am at the very bottom and can't see around the dark edges of what has become my life. A year ago, I had a career, a marriage and was finallypregnant after a long time of trying. First, I miscarried, then began to have severe vertigo...