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In this case I hope that for minor hearing loss with heavy synapses damages, additional growth factor therapy provided by hidden hearing loss researchers could be available, so that sound clarity and dynamics become optimum, as long as mixed therapies (Frequency + NT3 neurotrophin for instance)...

My fear is synapses couldn't be restored enough to be useful if hair cells are intact.

Who knows. Maybe 20 years or hopefully sooner. Actually it is more and more admitted that hearing loss can lead to dementia, and by this occasion launch alzheimer much earlier on persons with risk, so if this issue is more and more recognized, it may be shorter until a full cure

https://www.reuters.com/article/auris-study/auris-medical-to-abandon-hearing-loss-drug-trial-idUSL3N1NY3SI

This new topic is intended to gather such information, whether it be about side effects or even about controlling side effects. https://newatlas.com/stem-cell-hearing-cancer-risk/52108/

Many of us were asking the same question about the Bitcoin not so long ago : )

Maybe yes but only if the cause and location of sudden hearing loss is well known. Recently a quiet famous french actor got it. No cause was found first but after months of investigations, damages were located near his auditory nerve and it came to the conclusion that the cause was overuse of...

From what I remember on old tinnitus-hearing loss- hyperacusis forums and testimonies fifteen years ago, apart from corticoids injections which could be very effective in the case of acute inner ear noise traumatism if taken immediately, many tinnitus, hearing loss and hyperacusis sufferers were...

Ok but never underestimate the lying ability that is widespread among drug makers and physicians. Even hidden defect that were found during trials can be hidden once the drug is sold on the market. I had horrific side effects without any improvement when an ent prescribed me vasodilator pills...

The race for a cure is already launched and the successful winner will earn ££££$$$$€€€€, near 2035 in the worst case or near 2025 in the best case.

Back in the beginning of the mainstream internet, there were many horror stories from hyperacusis and tinnitus sufferers polydrugged by antidepressants and benzodiazepines especially rivotril which switched their brain off for weeks

Memantine is well known to be inefficient and even deadly in the long term. But when you tell it to physicians they often grimace because they are still stuck in an old pill paradigm

Let's hope that optimization of safety along with transparency will prevent crooks from hiding some dangerous side effects in this race. There was a link on the forum about a case in clinical trials for some diseases in China. The true seal of safety and efficiency might be the first and genuine...

@RB2014 Could you also tell us please how is the sharpness and comfort of your hearing along with tinnitus depending on volume and dynamic fluctuations when you wear hearing aids ? I mean : are the surrounding sounds becoming metallic / distorded along with tinnitus raise when surrounding...

There were some records (but I don't remember when and where) implying that cochlear synaptopathy was even responsible for some substantial threshold drops which could mean double hope for most of us if grown factors become the first treatment available

Marlino you are right, it is near 2025 that a common computer is expected to reach a human brain intelligence and near 2050 that it would reach all the human brains from the earth. It is at least guaranteed we would all be fixed if we manage to become old.

Among the new president's electorate there are many army veterans suffering from hearing issues and middle class baby boomers starting having hearing issues for some. Less money for abroad interference, more factories in the United States, if the bet of isolationist United States along with...

Suffering from mild hearing loss and tinnitus after prolonged noises exposures in the past, I seem since a few months ago to have actually decrease of the tinnitus and the mild hyperacusis (along with loss of hearing dynamics a sparkle) after a possible new ear trauma because it coincides with a...

Since the beginning of tinnitus (mild), barely manageable when normal speech in noise but far from before tinnitus, and huge difficulties with speech in noise when there is noise + reverberation like factories, under the rain etc , and much less punch and sparkle when listening to music, all of...

The title of the article is pure idioty. No pill has ever cured or fixed something when it comes to tissues that have been definitely destroyed in the human body. Novartis, Eli Lilly are praised to the skies but these companies have already killed hundred of thousands people with their pill's...

You're not alone. I had the same 15 years ago and I'm barely ok now, but it need to be fixed, it is vital for well-being again. I'm sure there are many other people who suffer from it but unable to explain that, like the older persons almost brain dead because of hearing loss or those for whom...

It is now proven that older persons with hearing loss are risking dementia, and there are many many older persons with hearing loss. There might be a honey pot for two markets : deafness (+tinnitus) cure and euthanasia. Hopefully the first overcome the second ! And therefore if efficient tools...

I wonder how could be done a clear display from each damage with current test tools since the amount of damage in each inner ear zone (neural, ciliary) should probably be known the most accurately possible in order to handle the amount of what must be repaired for each person.

By any chance are there any informations about decibel recovery after neurotrophic factors treatments in those preclinical stages ? I ask because there are many persons with decibel threshold loss, even you with no dramatic decibel loss can feel a lack of power and sparkle from what i...

For 15 years many tinnitus-hyperacusis-hearing impaired forumers hazarded this guess, at last an evidence is scientifically shown now.

Sorry for my ignorance, is it about spiral ganglions or an other nerve supplied zone ?

I took it for many years without any positive effect believing stupidly that healing would eventually be triggered. Among side effects there are Parkinsonian symptoms and the French FDA even wanted to discontinue it because there are no proven benefits at all.

Maybe not bad news that autifony stopped. Many oral drugs are often full of serious side effects, like Trimetazidine which was praised to the skies by some presumteous Ent doctors and drug representatives in last decades for tinnitus treatment. 15 years ago an ent doctor prescribed me a...

15 years ago in front of all those ear specialists, when one made hypothesis that damages linked to hidden hearing loss and tinnitus could be located in the spiral ganglions zone, 100% of them were shouting as if they heard blasphemy against their religion of consensus. One even told me with a...

Among his electorate there are many war veterans, and among those veterans, there are many wounded veterans waiting for cures for debilitating injuries like hearing issues. And if his project is not only promises, an isolationist usa might focus more on new markets like regenerative medicine...

In this case I'll leave it to all the courageous who will be the first to dare using the cures if they exist one day. Their testimonies will be crucial, hopefully they won't be betrayed like all the elderly persons used as guinea pigs without full recovery purpose in the allopathic medicine.

I want to be confident in regenerative medicine but I also fear because there are currently drugs on the market killing or disabling hundreds of thousand people every year (psych drugs, alzheimer drugs, statins, blood pressure drugs and many more) and however they are successful industries...

Military complex > wars > blasts > hearing loss, tinnitus, hyperacusis > needs > research, development, market huge rise of music festivals > likewise

After not having been believed by all those "physicians", that would be justice, but does research target mixed hearing loss therapies as well ? Because there are many noise injured - in addition to nerve damage - who seem to have significant hair cell loss too. Hopefully no agreement between...

Bioengineers show why lab-made stem cells might fail: Errors in DNA folding

Hopefully not too deep in the brain and close enough to the inner ear to hope significant relief in our lifespan since very little is known about the brain.

I believe the price could be the same as current most expensive hearing aids in the best case or the price of a cochlear implant in the worst case. I will save too, though for me it's more a luxury (regaining the overall 15-20 db loss to be cured, making normally music again, hearing in noise...

Or much later fully paid by your health insurance if you pretend to have hearing loss induced dementia :joyful:

Do you believe it's the journalist who's lacking correct knowledges or scientists who are wrong ?

Common sense makes me believe that it is like salamanders regrowing lost limbs. Not fully identical, a bit weaker but fully operational.

The eardrum becomes itself the loudspeaker and reports say patients gained a wider range of frequency and word comprehension but I agree the root of the disability is not managed. It is like current bionic limbs, more and more efficients in movements, probably reaching human capabilities in two...

It is the same for music hardware devices like synthesizers, mixing desks, effects etc. Softwares are currently nearly reaching the same sound quality as hardware for quiet cheap, though purists still notice a difference for sure. In the early 2000's virtual instruments and devices were still...

If I talk about my immediate feelings, I would say that starting from the early 2000's, the amount of information is exponential every 3-4 years but again, it's only studies on paper, and sometimes clinical tests on animals, but nothing significant about humans yet. At least one thing is sure...

I started to seek answers already 15 years ago, but forums and public reports were rudimentary. It was more talked about - understandably - the raw sufferings resulting from tinnitus, hyperacusis and hearing loss on audiograms. On forums, if one explained clearly and millimetricaly his or her...

So do I, therefore for music production I use a lot of reference mixes made by other bands since I lost a huge amount of dynamics with this sensation of flat porridge sound which also increases tinnitus.

Actually I have exactly the same issues as you though my brain has more or less compensated over time. Sorry I used the term post traumatic stress disorder which has made a mild misunderstood in the conversation because I don't know the scientific words to explain these emotional modifications...

I believe it is a kind of post traumatic stress disorder which could eventually diminish, without any drugs, but if natural supplements seem to help you continue with them if they are harmless. I say that because I suffered exactly the same. After many months overnight I listened to music again...

Until now public studies only reported research on either only nerve cells or only hair cells, unless i missed some studies aiming to target both in a unique delivery ?

RB2014 we are in an a crossing era. What was known to stay irreversible becomes slowly less inexorable. And people around 60-70-80-90 years - which have mostly hearing loss - usually don't use internet with the same fluidity as the youngers. Breakthroughs are sometimes seen as witchcraft too...

Many Otorhinolaryngologist are even not aware of recent scientific interpretations about inner ear wounds which however are public.

Teleshopping actors ?

I still buy gear too and the irony is that since acoustic traumas (caused by loud events after which I was always been told i'm mentally ill and that noise is not the cause until audiograms showed it many years after) I became a lot better skilled in audio and music production but unable to...

There was a case in a cosmetic stem cells clinic where a patient had bone growing in the eyelids after an injection. Therefore I either loose hope because of these stories though happening in non approved therapies, or I keep hope when reading reports about rats beeing more or less cured under...

With psychdrugs, on the mid term almost 100% have side effects and a huge part among those who don't die becomes brain dead and sick (diabete, dementia, liver destruction, rapid aging etc). Btw I have had a major brain and heart seizure which almost killed me because of an antidepressant several...

It's indeed a B77. I like old reel tape decks as well, with their thick and warm sound and their design. Hopefully if a cure for our conditions would eventually exist, I could use it again like before (mine is an akai gx-4000d) : using it as a drum playback while playing live in a band...

It depends on the number of hearing loss and tinnitus sufferers in the next decade, it might eventually become practically discount in the side of the patient if well reimbursed. Those last months there were many many forecasts about a futur hearing loss epidemic among the elderlies. And...

Retailers haven't sold all their white noise generators and hearing aids along with their almost useless gadgets yet, if a cure is sold fast, they are on the dole. Therefore the conversion to cure sales might be slower. A cure would make their expensive junk obsolete.

It's about 500000 persons (lots of seniors) directly killed by psychdrugs in the western world every year. I know diabete drugs killed in the past, as well as cardiac drugs (a healthy close relation died overnight) but I have no number nor timespan ideas for them. Idem for other drugs I can't...

Personally I don't believe in alternative treatments that work very good, unless it fits for few people. For sure, sound therapy, relaxation etc are harmless. Naturopathy and homeopathy are I believe a swindle but again, harmless for our bodies. We only can avoid ruining our bodies until a cure...