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I don't know but probably stay away from Agmatine also. Agmatine enhances antidepressant potency of MK-801 and conventional antidepressants in mice Just might have interactions with what you are taking.

I honestly don't know about Agmatine. I believe it has to do with nitric oxide which has more to do with Glutamate action. You are polydrugging to a point. My niece died with 5 meds, that caused depressed breathing. I have met a person who stared straight ahead, and say "I am on 4 meds, I don't...

The other company is out of the UK. I don't know much about them. Their version you have to refrigerate. I thought the worst side effects were hypotension, possible with interaction with other meds and the overrated diet, that honestly doesn't need to be followed closely. Boy was I wrong...

It is weird how long it takes to diagnose ADHD. Everyone thinks it is just people who can't sit still. There are two types. It has a lot to do with executive dysfunction, but executive dysfunction can happen in many illnesses. Possibly LSD might be better. It is trial and error. I am curious...

No, no noise events. I don't wear headphones, I hate concerts, I listened to sports talk. I really feel it was from Prozac or weaning from benzos or Anafranil.

Most people, sick of ADs, even without tinnitus are. Such a poor success rate. I know someone with visual snow and tinnitus and he gets more out of LSD. Wouldn't recommend that if tinnitus is the main issue. LSD has an effect on Dopamine. Dopamine can raise tinnitus. So can Serotonin of course...

I have done about four audiograms over 3 years. It is scary how mine match exactly the same over three years. Basically perfect, even the extended have matched. No hyperacusis. LDLs we're up 100+, yet I have intrusive tinnitus. Kinda throws a dent in the only reason intrusive tinnitus happens is...

I have found nothing. It is highly somatic, so I am working on my neck right now. It has been stiff for years. Some days the range of motion is so limited, because it starts hurting. It was either Prozac or withdrawal from benzos or Anafranil. I jumped back on both when the tinnitus started. So...

I know you have been looking for something to kick the depression. Have you tried 5-HTP? Not condoning the use but doses of 0.05 g of shrooms instead of 0.1 - 0.3 g seem to be helping people, to kick out of a depressive state.

Great to see. I wonder if it is feeling better mentally or just the Flupentixol. They don't prescribe that in America. Please be careful of the long term side effects or side effects that can sow up from antipsychotics.

Botox around my jaw did nothing for me. No measurable hearing loss, even with official high frequency test. I don't have a problem with hearing in noisy places (sign of hidden hearing loss). Most likely meds gave me mine. So I support your hypothesis of it being my dumb old brain. Desensitized...

There are so many factors. I still don't know if you are saying it is definitely the Ketamine? Changing benzos can have the effects of withdrawal. That is why if someone is to move from Klonopin to Valium, it is a slow adjustment over. Having had tinnitus for five years and having had my fair...

If I massage my neck muscles enough, fluid drains, from ear/sinuses.

So Nardil went through a change and was sold in 2003 to Pfizer. They changed the inactive ingredients. It went from 13 ingredients to 9. Some people came out and said it was not as effective. Two companies at least decided to make their own version as close to the original as possible and were...

Pretty sure NAC works on Glutamate and Glutathione. Hey, fellow OCD person here. I understand going down the polydrug world. I am finding you can't polydrug to fix OCD. I'm off ADs right now. Going through withdrawals. Still on Valium 10 mg and 2000 mg of Gabapentin. Fish oil is used to help...

Have you tried to get your neck muscles checked? There could be tension you don't know about. Honestly I find the Tympanic Resonance Hypothesis to be very fascinating. Look it up and see if it matches you. It is a long read, but described me and most of my symptoms to a T. If you have a fear...

Liquid titration is a good idea. Find a doctor who will support it. I believe it is fat soluble and you can taper using milk. Or alcohol titration. Move to 5 mg Valium possibly. But that might be excessive for 2 weeks of Klonopin use. For all the love on here for Klonopin, there has to be an...

That is a pretty jaw dropping amount of benzos.

I think it has much more to do with how well it reduces anxiety or it is literally calming down DCN activity. If it was purely neck/tension, Valium would be the better option, as I believe it is much better in muscle relaxation, but it isn't as great for tinnitus. Guessing because it isn't as...

Honestly it is used sometimes for things like Tylenol overdose at hospitals. It is safer than many people make it out to be. Are you thinking trying it for your OCD? Have you tried Inositol yet? Can be hard on the gut. Stomach cramps mostly, but some people with OCD swear by NAC and Inositol. I...

My daughter did it, but it is because she was somewhat on the spectrum. She has grown out of it. It is healthy to teach the iPod age about it, and to put on earplugs when mowing the lawn. But yeah I would monitor it. Also don't let her date the guy who drives the stupid trucks with the modified...

Doesn't have to. ETD, even without negative ear pressure can cause a weird feeling. TMJ, and neck muscles can play a part. If my ears feel full, I start massaging my neck muscles and they drain. Or take Sudafed PE. So no. Sometimes on this board you will get the feeling it means it, by reading...

What is hard is my tinnitus is the ultimate case of somatic. I am getting neck cramps right now and, when it cramps, the tinnitus stops for a second. I can also turn my head so far to the right that it stops, but I am talking like exorcism, turning. Any med that ramps it up, returns to base once...

Are you scared of some sounds or do they really bother you to the point you get angry? If it is just panic, I am with you, as I have OCD and anxiety. I think coming to these boards make my fear worse. But I always do what is wrong to do. It gets better. I have been to the movies, doors...

No matter what, I have been looking for a new way to control blood pressure. Added bonus is it would kill any vampires.

I do. I also have OCD. So reading about this or that increasing tinnitus, made me scared of sound. The fear tenses your muscles up, which doesn't help tinnitus.

My ear fullness is connected to my jaw/neck. Putting heat on my neck drains fluid from my ears. It is one of the few ways to drain my sinus and ears. The burning you said is gone. If it's still there, I was going to suggest opening your jaw and move the joint forward. It helped mine. I had...

This helps me. So does rubbing my hair around. If only a woodpecker would land on my head. I have no tinnitus days, ultra loud tinnitus days and in between. Sounds like it is in my head, intrusive when loud of course, but I think it is partly because I hear it in my head. Really somatic or...

I believe it is called Wellbutrin in America. Lots of stories of it causing tinnitus. Honestly a lot of people say it goes down later after quitting. Like up to a year, but it is gradual. So better as you go, until silence, if it is the cause.

It is honestly how I have come as close to habituation as possible. I have spent many nights going to bed listening to my 8/10 tinnitus. What I find is if I do it, I catch my mind wandering to different things and then tinnitus. Most days I would wake up to quieter days.

To suffer with depression and anxiety and then to have this happen. Stop beating yourself up over this. I have also seen on non tinnitus forums, people doing TMS, saying they got tinnitus. A lot of people have reported it. Isn't 140 dB worse then an MRI?

Tinnitus has multiple causes. Drugs can cause it and it can go away. TMJ. People on here put their eggs in one basket even when it comes to cures. A cure may fix it for some and not the others. @Greg Sacramento, sorry to hear you came from Boston. I am from Maine. Guess it isn't true that all...

Well that's the problem right there. He was using earmuffs, not a mirror.

Maybe going onto someone's post that is having soul crushing reactive tinnitus and saying, boy do I wish I had that back, isn't going to provide much help. I know it got off-topic and you meant no offense, but we have to be here to support. What the OP is going through is devastating for him...

Who says the treatment ends? Diabetics will always take insulin.

Lidocaine patch almost worsens my tinnitus, but interesting.

Didn't De Ridder question Dr. Shore's approach for improving tinnitus? If Lenire got approved in the US, then De Ridder could piggy back off that to get faster approval. It is easier to get devices approved once another one has, that is "close" to an already approved device.

I mean I might think about it. What is the end goal of the research? What are they trying to figure out? I live in Maine but work for a company in Massachusetts. Funny enough, my company's headquarters are in the same building as Decibel Therapeutics. I just want to knock on the door and say...

I felt it was a sort of, enough inquiries already, shut up.

Excuse my language. Ah fuck nuts. Does your tinnitus sound like it is coming from the brain or the ears? Is your original cause noise induced? Did it go down after removing the med? Good luck.

Did it worsen it though? My therapist gave me some insight into myself. I do horrible with antidepressants. Definitely not bipolar. She said I seem to suffer from dysthymia. I knew I had OCD, anxiety and now this. I did VERY well on Ketamine IV. Troches, I got addicted. I saw some users with...

Luckily a sample of one, when one is @linearb, is better then most. He has been a long time, great addition to Tinnitus Talk. I know you aren't saying he isn't. Just gives more hope than a random person showing up and saying this worked, maybe or maybe not answering questions and then moving on.

I know, obnoxious isn't it? I find it kinda poorly written to talk about it being a disservice and would only cause frustration if this or that happened in his response. There is going to be frustration no matter what.

I think I was speaking to Deb at the beginning. Really so lost on what point you are trying to make. Sorry I think there is a translation issue going on or something.

How do I know I have OCD? How about everyday before tinnitus, having intrusive thoughts about hurting your family or having relationship questions, then spending endless hours trying to look for reassurance. I have tried Keppra, but for other reasons. It didn't do anything. Ketamine at lower...

Answer it or not, it is up to you. Have you before tinnitus and all these symptoms, had anxiety, maybe sometimes debilitating?

No problems with Cialis for me. I mean um someone else I know. I don't know if Maca Root or Horny Goat Weed work in the same way. With performance anxiety maybe a therapist specialist in this domain might be more helpful then meds, if it is worsening your tinnitus.

Could you explain what you mean by it helping central tonal tinnitus, but not buzzing? Mine goes day of near silence, next day starts to rev up and can be static in my head but sounds like it is near my ear, by the third day it is dentist drill in my head. Then next day silence again. So at...

For some reason I could tell you have OCD. I do too. One sign is how well researched the person is. I will mention that I tried Abilify. Go real slow or start at the smallest amount. It didn't work for me and I got uncontrollable intense blinking. It was so hard to explain. Not Akathasia but...

My mother has it. She has Alzheimer's, so they did an MRI and it was a reported finding. She did have tinnitus for two years but it went away. They monitor the growth every year to make sure it doesn't press against the brain. Surgery is a last resort because you lose your hearing a lot of the...

I would be careful of chiropractors. I am sorry I don't believe in it. You seem like someone who does deal with regular doctors. I don't blame you. I don't think they can help. Just saying be weary of "natural" methods. Hypothalamus damage doesn't even sound close to be anything real, unless you...

Good Lord man, having that stuff happen on a bike and a car and yet you are thinking of flying?

It is tough to tell. The only way to know is to try. I am going off 40 mg of Valium and at 10.75 mg now. I am also switching from Anafranil for OCD to Nardil. I will only know by trying if I get better. Ketamine was doing great for me, but I got addicted to it and it made the tinnitus worse in...

Look up the Stamets protocol which is microdosing + Lion's Mane mushroom + Niacin, or Fadiman: https://microdosinginstitute.com/how-to/microdosing-protocols/

I don't know if I have ever heard of switching from Ambien to Valium. That is usually for getting off Xanax, Klonopin, Ativan. I would try to cut your dose 10%. Most doctors won't even make the switch to Valium. They will laugh or just kick you out. Not saying they are right to laugh. They just...

No, microdosing never leads to tripping. If you are sensitive to meds, try at 50 mg and keep upping over some days to 300 mg at most. Of course you can feel side effects, like irritability. I don't take well to most serotonogetic drugs and musthrooms work on serotonin. A trip usually wouldn't...

This is great. Thank you for coming back and reporting. The only sad thing is that L-Carnitine made it louder. It is supposed to be great at raising libido.

I have been working in IT for 17 years. Everything from server administration to now security engineering. I guess I have never thought of myself as a computer toucher. It kinda sounds like the computer isn't consenting to what I am doing and I should be jailed. To be fair the operating system...

I have tinnitus sound coming from my head. Possibly from benzos. I would like to know if the one ear bud thing matters and if Dr. Shore thinks her device would help. Also someone said that the device is targeting the neurons that create the tinnitus. Guessing they are talking about fusiform...

No. I am one of the mice they gave tinnitus and tried AM-101 to fix it. It didn't help the tinnitus but now I know English, American Football, how to type and surf the internet. #MiceHateTinnitusAlso