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It's likely not for the rest of your life. Maybe only 3 - 5 years.

I had burning ear pain in 2019-2020 from 1.5 h commuting with my car. And I was lucky that COVID-19 came and I could sit in my apartment 24/7 with earmuffs and recover as I could work from home. Probably otherwise I would have completely destroyed my ears before quitting my job. I can assure you...

This is maybe correct for someone with healthy ears. But for someone who already has tinnitus and hyperacusis, this is bad advice. One should not neglect the pain signals that the body is sending. Maybe some also improve by ignoring the pain, but you are then playing with fire as you could end...

Moonwalk against the Occlusion Effect Could be the title of a paper in a hyperacusis journal.

Probably tinnitus will be solved by Darwinism before a working treatment is found.

I am not so sure if you can say that Russia allied with China. China probably does not want to break all economic ties with the west. I think a few billions each year for a few years is possible. By the way this gives probably a good boost to the US defense industry and Europe is now buying...

I am wondering why there is such scepticism in the USA when it comes to supporting Ukraine. I think there was no such scepticism during the Afghanistan & Iraq war and now we have a war in Europe. And they only need military aid and money. No US trooper will risk his life there.

I read somewhere that mostly this is a blood flow problem. So you could try supplementing with Magnesium & Potassium, which are also good for the ears. May not be a short therm solution, but worth trying.

That's how I understand the upper left quadrant as well. For those the treatment increased loudness, but reduced TFI. I am also wondering how that's possible.

Heal in isolation.

Fortunately, for most, tinnitus improves. So finding someone like that is not difficult. But did the pill in this case help him? Maybe he would have had the same improvement if he took a sugar pill.

Improvement takes time in the order of years. Hyperacusis without tinnitus is quite uncommon. I had 13 years tinnitus before I got hyperacusis.

It has improved. I have the feeling that 24/7 hearing protection loosens up those ear muscles and thereby improves hyperacusis. I have also read elsewhere here that tense ear muscles are related to hyperacusis.

In a coffin you have the problem that there is no ventilation. But you can buy a sound proof cabin. The ones that I looked up online had a noise reduction of 30 dB. I am wearing foam earplugs at night which probably has the same level of noise reduction, but for someone who isn't able to use...

I guess before hearing regeneration drugs come out, Prof. Thanos will have his RL-81 on the market.

It wasn't a silent MRI. That was just advertised on their website this way.

This combo of foam earplugs + noise-cancelling headphones works great for me when driving. For flying I am a bit sceptical on use of foam earplugs. But I will not fly anyhow until my hyperacusis has improved to a point where I feel confident in doing so.

How do you equalise pressure with foam earplugs during take off and landing?

Load up on Magnesium.

The reason is probably as it was discussed in the OTO-313 thread: seizures per month is probably much easier to measure as an outcome versus tinnitus improvement.

There are also medications for other conditions which are not objectively measurable like pain for example. Why do you think tinnitus research should be stopped? Because the risk that trial participants take is too high? I think that's everybody's free decision.

The Ebselen from Sound Pharmaceuticals seems to be the most promising drug currently as they have completed the Phase 2 trial and are now starting Phase 3. If it does not fail, it may be available in a few years.

Hi @Lesky, glad to see you are still around. Hope your pain hyperacusis has improved? You created this thread nearly ten years ago.

Tinnitus is very individual so probably no one can tell you what the future holds. But it's a very good sign that you have experienced improvement. So there is no reason why it shouldn't continue to improve if you relax and protect your ears.

Ok, that's not nice. But it probably hasn't set you back two years. Just remember that we always need to wear hearing protection as those random events can occur anytime. If I know I have to talk to someone or if I am in the office, I am always wearing those musician (or Christmas tree) earplugs.

What caused your setback? If you load up on Magnesium & Potassium and protect 24/7, it will also get better this time, maybe it will take a little longer. It is shitty that we have to live like a recluse for a few years, but better to do this to have some quality of life in the future. After two...

I haven't tried earbuds, but foam earplugs + noise-cancelling headphones is probably the best protection you can get when driving a car. It's also more comfortable than normal double protection as the noise-cancelling headphones do not sit so tight on the head.

Tinnitus seems to be also quite stable. Foam plugs seem to work quite well for the wind and guys cutting trees with chainsaws. (2/2)

First time in three years I was mountainbiking in our forest here. Only my legs and butt hurt and not my ears as it should be. (1/2)

It's in most countries not available anymore. Interestingly I found some entry in a German medical forum where someone is asking for an alternative for Flupirtine as he was using it for years for treating his tinnitus. Flupirtin gibt es nicht mehr? On ClinicalTrials.gov there are just 3...

If I had to choose between tympanometry or LDL test, I would select the LDL test.

These Gamma-secretase inhibitors were already used by Audion with not really fantastic results. So unless they have a complete different approach, results here will not be groundbreaking.

I can understand that he is not commenting on XEN-1101. That's like asking Otonomy about FX-322. It would be nice to have some update on his RL-81, however. I think the Tinnitus Talk Podcast interview was in May 2020 and there he said that clinical trials probably will start in a year or two...

It has improved. So sounds like kitchen fans and running faucet don't annoy me as much. Most improvement I am aware of is with computer audio. 2020 0.5 h of Teams conference gave me burning ear pain and now after 2 h I may have some slight ear tingling sensations. Clearly I try to reduce those...

Wearing hearing protection 24/7 is probably the best decision that I have made in the last couple of years. I am doing this around 1.5 years now and my pain hyperacusis and tinnitus have reduced.

Running did spike my tinnitus, so I stopped doing it. That was before I got hyperacusis. But probably running with earplugs will produce a huge occlusion effect, so I will not do it. Maybe I will start bicycling when this has improved to a certain extend. But if this has no effect on tinnitus...

Yes, if you don't already have, get some Peltor Optime III earmuffs and start supplementing with Magnesium.

Maybe you need a quieter vacuum cleaner. There are ones which are under 60 dB loud today.

Congrats for your improvement. Especially after huge noise exposure.

But one should talk only with someone whom one trusts about this. There are cases here that ended up in psych ward because of this and this does not help hyperacusis in any way. There are also no medications for hyperacusis, so one is just left with the option to avoid all triggering noises and...

It was not pain, but if I slept without earplugs I could feel my ear muscles were tensing up in the morning. I don't know how it would be now. But ears take quite some time to regain some strength. So I will continue to do this for the next few years.

My tinnitus has improved by doing 24/7 protection. Initially it was also too bad to sleep with earplugs. However the 10+ hours of sleep like a baby is also not possible at the moment for me.

Yes, since late 2020. Improvement came after months. But I am still protecting. I feel my ears need a few more years of protection.

It's probably only dead silent at night when you live in the middle of nowhere. Otherwise cars are passing by, car doors are shut quite loudly, drunken youngsters, ...

It's now two years ago. It was some gradual improvement, but I am not over it yet. Still using hearing protection 24/7.

Yes, the spike did lower. But that took quite some time. I didn't use double protection, big mistake.

This is the reason why there is a delay: And that's probably not so unexpected knowing the side effects of Trobalt. I wouldn't want to risk severe visual snow, but that's everybody's choice. So he seems just being serious in making a safe drug. I wouldn't call him off. That's the same as what...

I would add Magnesium and Potassium citrate to the list.