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    Otonomy OTO-313 — Treatment of Tinnitus

    For anyone that is considering applying to the OTO-313 trial, the doctor that performs the injection can find out whether the participant got the placebo or the actual medicine, if the participant were to have an adverse event or tinnitus gets worse. Does anyone have any experience or knowledge...
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    Steroids: Prednisone / Dexamethasone / Others (Oral and Intratympanic Injections)

    Steroid pills does lower my tinnitus a noticeable amount during the taper, but after the pills, the noise gets louder. The injections stopped the tinnitus for a few hours but then it returned louder with a change in tone, went from a loud buzz to a high pitch ring with alternating periods of...
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    Otonomy OTO-313 — Treatment of Tinnitus

    @ChrisBoyMonkey, Am I understanding correctly that they intend OTO-313 to stop tinnitus no matter the cause? I have seen your user name around the different forums, do you think the machine based treatments help people with hearing loss? I don't understand the different claims that 90% of...
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    Otonomy OTO-313 — Treatment of Tinnitus

    Why should this be a 1 to 4 week treatment? I don't know how a person with acute onset could even get in a trial within 4 weeks... Confused as to why 1 month is a cutoff, I may have access to this sometime, so I am eager to hear from ChrisBoyMonkey on the placebo vs real drug stuff, and...
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    Otonomy OTO-313 — Treatment of Tinnitus

    Does anyone know if participation in a OTO-313 trial causes hearing loss or damage that would prevent use of drugs such as FX-322 or Hough Ear Pill when available? I am confused at to whether its a good idea to pursue trials with acute tinnitus or try to cope till something like expanded use or...
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    Misoprostol — A Treatment for Tinnitus?

    I didn't think access would be that difficult since it's used to protect stomach from ulcers and NSAID use... I found this online... One option for self-managed medication abortion is misoprostol, one of two drugs used in the Food and Drug Administration (FDA)-approved regimen for medication...
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    Misoprostol — A Treatment for Tinnitus?

    http://www.tinnitusjournal.com/articles/tinnitus-treatment-with-misoprost-a-blinded-and-placebo-controlled-study-11059.html I was thinking of trying this. From the study conclusion: "...The tenacity of present study is that, we have included a large sample, with well-matched tinnitus...
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    Otonomy OTO-313 — Treatment of Tinnitus

    Thanks for the positive comments, this is hard to deal with...
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    Otonomy OTO-313 — Treatment of Tinnitus

    Thanks everyone for your replies and advice, I really appreciate the positive comments.
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    Otonomy OTO-313 — Treatment of Tinnitus

    F-u-T, Thanks for your reply I think it was from a flu vaccine, but I have been told its due to mild to moderate hearing loss in the high frequencies, stress, blood sugar spike, viral, unlucky, and every thing in between. Been to 4 ENTs as of today, and 3 audiologists working off the initial...
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    Otonomy OTO-313 — Treatment of Tinnitus

    @ChrisBoyMonkey, Would you let me know about your experience with the OTO-313? It's an hour and a half trip to the place to get it done, they told me it had to be so many weeks after I was off steroids, which puts me in January. I am considering getting the steroid injections in January...
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    Otonomy OTO-313 — Treatment of Tinnitus

    @ChrisBoyMonkey, did you find out about whether you received the actual drug in the study? I had been talking to them about the OTO-313. I thought that the Gacyclidine was a safe medicine for injection, so now I am at a loss. My tinnitus is new so I have just finished steroids and it's gone...