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UPDATE: I've taken Sulodexide for almost two months. The main side effect is an some aggravation of my pre-existing gastric reflux disorder. But bearable. The main conclusion so far: it's helping my tinnitus somehow. It doesn't really treat or cure it, but it somehow reduces, not the base...

No, Saffron is not long lasting, and actually it seems that your body quickly adjusts to its effects, so it's not a cure. But it may relax you. Saffron seems to work like an actual anti-depressant drug. Something like that: Saffron (Crocus sativus L.): As an Antidepressant Here is the topic...

Unfortunately, there was a small spike again yesterday, so in addition to the Sulodexide, I used the only supplement (from many I tested) that actually works for me: natural Saffron spice, extracted by 20 mg of vodka. I awoke in near silence (the silent days are the ones I forgot I am having the...

Update: I need to say that I am trying Suledoxide after very, very huge spike I got during my flu/pharyngitis episode. After I started to take the pills, the spike dropped to the baseline. I doubt that it is because of Sulodexide, probably just a lucky coincidence. I will continue to take the...

In the beginning, yes. However, I believe that after 30 days, I will increase the dosage to 4 pills, since I have read that it is a very safe drug used for preventive purposes, etc., with no risk of bleeding. And I opted not to take it with Melatonin because (just in my opinion!) Melatonin...

Ok, starting Sulodexide today: Vessel Due F 250 LSU capsule. Twice a day.

Hello, I will try Sulodexide soon according to the protocol described in this paper which looks really serious. Will update. Sulodexide Monotherapy in Chronic Idiopathic Subjective Tinnitus: A Randomized Controlled Trial

I got Sulodexide and Melatonin. I will try this protocol.

Really sad. Would you try to add 3 mg Melatonin before the sleep as in the study?

Hi, in the beginning I was carefully taking ~ 20 units twice a day, soaking them in the warm milk or vodka. Later I was using just a small pinch of Saffron, not measuring it. Actually now I take it only occasionally, maybe twice a week. Something happened to me, I am not so much bothered by...

So ~6 weeks of Saffron use. I definitely benefit from it, and will continue to use. It helps somehow with the mood, however, it is not a cure for tinnitus, of course. The effect is very strong in the beginning. Later the body gets adapted and you need to increase the dose, and still the effect...

An update: I have continued to take Saffron. My elevated mood has disappeared now, I have some slight anxiety attacks (I had anxiety problems before the SSHL), in general my mood is not good, but I don't feel depressed, just tired of being in the anxious state. Most interestingly, I am not...

It's been 2 weeks since I started taking Saffron. Objectively speaking I cannot say that the tinnitus loudness decreased, but I noticed that I somehow don't care so much about tinnitus anymore. I keep finding myself sometimes forgetting about it, for example, I no longer use masking music. And I...

I got SSHL, tinnitus, with perfect sugar level, no insulin problem, and totally support @linearb's post above.

Long story short, I enjoyed the movie Sound of Metal, however... there was almost nothing related to the tinnitus. Maybe only the feeling he got when the cochlear implants were turned on. The constant disturbed noise. I wish someone would create a movie about a tinnitus hero, and obviously...

Some additional information that might be useful: "Most dried Iranian saffron pistils more often contain about 35 mg crocins per gram. At a concentration of 35 mg crocins per gram of saffron pistil, we’d need to prescribe 100 mg twice per day to match the dose of crocin used in the studies...

I paid 10 EUR for 1g in my local natural herb store, which should last for approximately 20 doses. I would say that this is probably one of the cheapest supplements I have tried for my tinnitus. And actually this is the only supplement that has a decent confirmation about its above-placebo...

It's been 6 days since I took my first portion of Saffron. I am also continuously running various kinds of custom made sound therapies. Today I woke up and this morning is probably the best morning I have had since the onset of the SSHL. The tinnitus is somewhat there, but not so intrusive...

NAC is one of the few supplements I am still taking. It helped me well with the elevated liver enzymes at least. This was very nice and unexpected. Actually it protects my liver while I am drinking, this is incredible. No surprise it is clinically used to save the liver from fatal poisoning...

I would be lucky to announce that Tinnitus Mix worked :) However, unfortunately, for me it works as masking sound at best. I had no problem with that industrial noise and quickly adapted to it, I can sleep with it no problems. But unfortunately I had no long term effect... But what the hell, I...

I started to take the Saffron. I know how to recognize and I immediately can feel its serotonergic effect: good mood without reason, vivid dreams. However it is unbelievable that it kicked in so soon, just in 3 days. The tinnitus loudness is not affected, it seems. However because of good mood...

Could you please elaborate more on the pills?

NAC helped to regulate my liver enzymes, but did not do anything for tinnitus.

Despite official treatment protocols, there are some doubts if steroids can actually help at all. Because nobody (due to ethical reasons) does the studies with control group (people with ISSHL who would not get any treatment). These doubts came from anecdotal evidences that similar percentage...

I have been using NAC for a long time, the only benefit I could find is that it regulated my liver enzymes to a normal level, they were higher for the last few years. I saw some posts here that NAC is better than L-cysteine. I am well aware that most publications use NAC to check its...

If the cause of your tinnitus is TMJ, there are quit a several ways to try to fix that. Have you tried them all, including botox? In addition, if you are in such state as you describe it, you should agree that you will lose nothing if you pay a visit to a good psychiatrist to try medications...

The first month has passed. The tinnitus got the second tone sometimes, the new tone is beeping like Morse code. The loudness has not changed - at least I think so. What is interesting, that somehow suddenly I felt much more calm about it. Like my perception of it has changed. It is here, it...

Betahistine is a medicine called a histamine analogue. It works by increasing the effect of a histamine. So it is an opposite of antihistamine. And yes, scientific papers show that it does nothing for tinnitus.

http://www.residualinhibition.com/residual-inhibition.pdf I started to experiment with this. It seems that using frequency generator app to play 8000 Hz , I can inhibit my tinnitus for a moment. Very interesting. But I need to make it very loud as I am partly deaf on that frequency so a little...

It seems that I can activate the residual inhibition effect by generating 8000 Hz pitch sound loud enough - very interesting! And it seems that my idea to leave the damaged ear in the total silence is not good at all: "Roberts’ 2007 paper discusses a theory that treating patients early in the...

I got strong tinnitus due to ISSHL 3 weeks ago. I started Tinnitus Mix therapy 5th of August as per the instructions mentioned. The therapy sound itself does not bother me that much actually. After first night, no improvement noticed, I will try for a few nights more, plus will try to listen to...

The audiogram done the next morning after the onset. In addition, now I started to notice that my tinnitus somehow feels not so annoying/maybe slightly better in the mornings, yet during the day it strengthens again and become hardly bearable in the evening. It reacts to the sounds, I guess...

The same reason why there is still no cure from tinnitus: it is very complex and possibly has several - or maybe even many underlying different mechanisms for each individual. Alcohol increases GABA so it can be linked with the hypothesis that at least for some people the tinnitus mechanism is...

Meniere's typically comes with very strong vertigo, not simply dizziness, and usually the low frequencies are lost, not high ones. So not likely. Unless, of course, it will happen again after some time. I will have MRI after a month, but not sure if somebody will be able to see something.

Unfortunately I became the member of tinnitus community as well. I got some good insights from browsing Tinnitus Talk so decided to share my case too. 14 July suddenly felt dizzy simply sitting in the front of PC. I tried to stand up, but I was feeling like heavily drunk. In the past I had some...