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I was on MRI last week. I advise you to use earplugs. I bought 3M E-A-R Classic and combined with headphones (they will provide you with them) it was OK. Machine noise is rather in the low or middle frequencies. It caused no damage to my ears. I have also mild hyperacusis. My biggest concern was...

Unfortunately, clinical trial (ID: NCT04066348) of Etanercept has not even started. Delayed probably because of COVID-19. To make it even worse, inclusion criteria include: Tinnitus associated with blast- or noise-exposure of at least a moderate severity as defined by a score of >25 points or...

Zopiclone IS OK. I have used it daily for 4 months. Some people have used it for years. Interesting report here: An approach to long-term sedative-hypnotic use Forums are full of prophets of doom spreading pharmacophobia. People with positive experiences usually don´t even have motivation...

Roy, did you consider a cochlear implant or treatment with Zoledronate? According to this study it could help: Bone disease medications may reverse hearing loss Regeneration of Cochlear Synapses by Systemic Administration of a Bisphosphonate Naturally, dosing regimen for some effect in humans...

Where are you from? If you live in US , you can try some orexin blocker. Dayvigo for example.

You can roughly check your high frequencies here: https://www.audiocheck.net/audiotests_frequencycheckhigh.php I have -75 dB/-50 dB L/R at 8 kHz on standard audiometry, but I can hear something up to 11 kHz. Obviously - start with your volume DOWN.

Of course. That is true. What if patient #5 had lost some IHCs but still had peripheral axons. They could reconnect. I know that it is unlikely, but that can be a reason why it happened only in one patient. But as I said: who knows.

Yes they have.

He says central axons, not peripheral axons (between IHC and SGN). It is a big difference. One more thing: Without central axons, cochlear implants would not work.

Yes I know it is not a synaptopathy drug. I wrote "As far as I know, FX-322 DOESN'T influence this". Charles Liberman says that SGNs last for decades, not their axons. Axons and synapses degenerate quickly. SGNs survive decades without these axons. Link to video, time 4:50-6:00:

What about continuous loss of IHCs' synapses from SGNs? As far as I know, FX-322 doesn't influence this. Charles Liberman says that synapses and axons degenerate most rapidly. If IHCs are left without synapses, it's almost the same like being dead. That would result in distortion and reduced WR...

Are you sure that all their studies were non-faked? Do they even know that there is something like ASSR test?

I suppose the subjects that more than doubled their WR score will be the same who faked their WR score in recruitment the most.

Firstly, buying biotech stock is support only if you take part in IPO or during capital raise. If you buy FREQ after that, it is not support at all. Secondly, I appreciate the time and effort of many people here. But unfortunately, it doesn't bring diagnostics or treatments much closer. More...

That is exactly what I think. If you ask people to financially support Tinnitus Talk, or research, they don't have the money. But they have enough money to buy stock...

Roy, according to the study in the link, you can have hearing loss even with perfect audiogram. Study shows hearing tests miss common form of hearing loss

This thread has thousands of views, but nobody decided to financially support The Bionics Institute's tinnitus research. So sad. https://www.bionicsinstitute.org/Appeal/tinnitus-appeal

I'm really looking forward to the episode with Dirk De Ridder. He is my favorite scientist in the field. Here is the link to his presentation from March if you are interested.

I just stumbled upon The Bionics Institute tinnitus research program, and they have raised just $3000 AUD from their goal of $100,000 AUD that they need to raise for their current program. OMG. Is it really so hard for people here to raise $100,000 AUD? There are more than 30,000 members here...