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I've been doing a lot of thinking this week, trying to untangle the web of ear damage symptoms that have followed my acoustic trauma, and I've come to a similar conclusion. I have high frequency hearing loss that is greater than yours and Benjaminbb's (30ish dB at 6 kHz and 40ish dB at 8 kHz)...

I'm not aware of the specifics on that. You can always try contacting them. This is a good question. I'm not well versed enough to know the answer (I'm not sure anyone really is when it comes to the mysteries surrounding this condition...), but it really boils down to whether the damaged cells...

Not sure what you mean by industrial approval, but the first trial is supposed to begin in the fourth quarter of this year.

Huh, never thought of that aspect. Interesting speculation for sure.

Yes, according to these slides (page 17 and 36), there were 4 (out of 13) subjects that saw 10-15 dB improvements at 8 kHz. https://investors.frequencytx.com/static-files/6d161090-16f5-49f4-9606-8caceb5a88a1 It also looks like they only tested up to 8 kHz in the trial(s) that the stat comes...

Well, FX-322 only really touches the higher frequencies, so yes, that's where it works best, because that's the only place it could work. The only audiogram improvements in any of the trials were seen in a few patients at 8 kHz. I don't believe any of the extended high frequency audio testing...

In theory, yes. In pure terms of physical proximity, that's the case. But there might be some other factor at play. The crux of this question is very interesting to me and I hope they're trying to figure out why the outer hair cell improvement is lagging behind the inner, especially in the...

Yeah, just over two months since onset. Just going to give it some time and see how things go.

Very interesting. Your hearing loss issues closely mirror my own. Moderate loss at 8 kHz and my ultra highs are pretty shot as well. Had the steroid shots a couple weeks back but it doesn't appear they've done much honestly. Still glad I had them done. Maybe I'll have some delayed improvement...

What caused your hearing loss and what frequencies was it at?

I'm very interested if the potential for multiple doses is there as well. It seems like the scientists at Frequency Therapeutics sure thought so, but making the dosing schedule so compact was obviously a big mistake. We'll have to wait and see, but I'm sure at some point in the future after the...

I've seen this image before but never looked that closely at the differences between regrowth re: inner and outer hair cells and at different frequencies. They treated the mouse cochlea in a more direct manner than your typical IT injection, right? Would that change the outcome for outer hair...

That's very interesting. Could you expand on this a bit? Did you notice no improvement for a while after the shot and then gradually noticed it coming back over a certain time frame?

Thanks. Hoping you see some positive results with this. Definitely worth a try.

Definitely going to follow your results with the PRP. What level and frequencies of hearing loss do you have?

Very interesting, never even heard of it before, but have seen studies about BDNF and NGF in regards to tinnitus before. What country did you get this prescribed in? Seems like it might only be a potential treatment in certain countries. Definitely update us on how it goes.

Scan was pretty long. 30-40 minutes. And yes, I definitely developed tinnitus afterwards with my other symptoms. It comes and goes though. It seems better now than when it started at least. Do you have ear fullness/pressure along with the clicking and popping?

Very interesting. I recently experienced an acoustic trauma as a result of next to no protection during a very loud MRI. The earplugs they gave me were garbage and kept falling out and I had no clue about the loudness beforehand. I've had some on and off Eustachian tube issues beforehand, but...

Glad to hear it. Did you have any hearing loss at all or just the tinnitus?

Did anyone else experience obvious fluctuations in their hearing loss post acoustic trauma? Mine was just over a month ago so I'm still mostly in the acute stage. Tinnitus fluctuates too, but that seems very common. To me, it seems like the fullness and the hearing loss are very connected in...

How long/what dose was your course of steroids?

@Seabert, any update? I've started taking this due to some positive results for high frequency losses of a couple people in this thread.

I found an ENT that does them and you were correct, he was willing to do both ears at the same time. First one has been completed. Both my hearing loss and tinnitus seemed somewhat better the day after (yesterday) but I'm not sure about today. Things still seem to be fluctuating so it's hard to...

I'm kind of wondering something similar. If we try FX-322 and it doesn't give sufficient results, would this at all interfere with the ability of FX-345 to work later down the road? I do have some moderate high frequency loss that I'd love to fix, but definitely want something that gives the...

Gotcha. I'm with you on that, if I can get them done and they end up working, I'll take however many they are willing to give. Still a work in progress right now, it seems many ENTs hold back on giving them out. Thought it would be easier with actual documented hearing loss on an audiogram and...

Has anyone who has received the steroid shots had it done in both ears during the same treatment? Not necessarily at the exact same time, but one ear one day, and the other a day or two later? Anything like that? My issues are bilateral so I would need to double up and I'm trying to understand...

@RadioKid722, thanks for the post. Yeah, I'm working on finding several new ENTs for next week to see if any of them would be willing to do this. Any improvement would be worth it at this point. The only thing is that my hearing loss is bilateral, and it seems as though the injections are more...

Thanks for the response. I feel for you, this has been hell for me given how much I valued my hearing before this, and more severe hearing loss than what I'm dealing with can't be easy at all. I know steroids aren't close to a guarantee, but I want to throw everything at this in hopes that...

Hey, I recently acquired tinnitus as well as high frequency hearing loss (and a couple other symptoms like fullness, etc) due to acoustic trauma about three weeks ago. I've taken a seemingly reputable audiogram test online that showed I had moderate - moderate/severe hearing loss at 8 kHz...