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Are there any information on the next version of this device out? From where do you know that?

What does this mean for the company "Cognosetta" and their product?

What happened to Cognosetta? Their website has been offline for months... Does anyone have further information about them?

Spending too much time on tinnitus research destroys me. It's depressing that there are no treatments on the horizon.

Nice find! This is really exciting because this is a completely new approach. What solves the problem, is that everything has to be regenerated perfectly in the right place and order to regain function. They try to reprogram the inner ear cells to turn their biological clock backwards. I guess...

AudioCure's focus is on "acute hearing loss and acute tinnitus".

First poster I'm interested in: Poster Session 1: SA225 Drug Discovery for Noise-Induced Tinnitus Based on the SBAD Model (Joseph Pinkl, McKenzie Rice, Jianxin Bao) Particular questions: What's the development stage of this treatment? Is there a timeline for upcoming milestones? Second poster...

I got an answer from Professor McNaughton: "Thank you for contacting me. Our work has shown that tinnitus is driven by the HCN2 isoform (protein conformation) – but unfortunately the HCN4 isoform is critical for a normal heart rate. What we need is to develop a drug that can distinguish between...

Why? They mentioned their timeline on the Tinnitus Talk Podcast. Everything is according to plan... They stated that they are planning to release NHPN-1010 in the mid-2020s.

I found further information on their website about the NHPN-1010 launch: "One of the aims of the research at HEI is to move the findings from the research bench to the clinic. Accordingly, the demonstration of the effectiveness of a combination of antioxidants on preventing hearing loss in...

I doubt what you are saying. The veterans' compensation for tinnitus in the US alone is higher then your stated hearing aid market value. Why are you so pessimistic? People need hope, that's the only thing we got with this terrible affliction.

What are the realistic facts, that you are talking about? Let's take a view from the economic perspective: Companies want to make money in the first place. Investor/company decisions don't exclusively depend on how much people die from a disease. The hearing regeneration market is a big...

I got a response from Gateway Biotechnology: "We just received a favorable FDA response for our drug development plan, and now are in the process of applying for further funding to complete our IND application. Hopefully, we can start our clinical trial in two years."

Tinnitus is hard to measure. In addition, trials cost a lot of money. I think that these are the main reasons why they are not focussed on tinnitus. They also stated that these medications (XEN1101) might be potentially helpful for other neurological diseases. I guess they are aware of the...

When can we expect clinical results/data from the XEN1101 Phase 3 Epilepsy Program? At ClinicalTrials.gov they estimate the study completion date in October 2025.

I found a new article about Mr. Clas Linnman's approach. It's an interesting interview with a message of hope. Mirror Therapy for Tinnitus https://catalyst.harvard.edu/news/article/mirror-therapy-for-tinnitus/

Great find. Transformative therapeutics have never been closer to becoming reality. The Kv 7.2 modulator race is on.