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Trying to work on my business startup with so many unexpected obstacles has been stressful. Hurricane Helene has delayed me further. Hope this is the last roadblock.

PTSD related memory issues are always bothersome.

The greatest accomplishments can be achieved simply by having the courage to ask friends for help. I'm so amazed & inspired by the progress.

Ngl the filters on this site can become a puzzle. I get why they're there, but I find myself trying to change every word to fix it LOL.

I'm so proud of you guys! You're all doing incredible work.

The staff of Hub/Talk are sincerely wonderful people, & I'm immensely grateful for their hard work in raising awareness & running this site.

A PTSD diagnosis is scary.

Back after a lot of work in my personal life. Tinnitus is still a pain. Will be working on related business startup now.

Someone randomly liked a post from this old thread, so, I'm just going to give an update saying that I stopped around COVID-19 after making a profit of a few grand and didn't want to do it anymore because of life circumstances stressing me out. I'm now a college graduate with a robotics degree...

A lot of people forget that 70% of the world aren't altruistic in nature.

Got sick on Thursday and now my left ear is bothering me more.

Yes, this is a weird situation where much of the anecdotal reports on growth factors on Tinnitus Talk do not match the results of the scientific studies, including those that involved human subjects. I have wondered why this is. It would be unrealistic to assume all these studies were fake, but...

Principle Component Analysis?

His conspiracy theories were a bad influence on my anxiety back then and it really disturbed me how far he was willing to go to slander/insult people. Looking back, I'm amazed with how they tolerated with him for so long. Although I'm now convinced he handled everything wrong, I'm grateful on...

I'm going to find a way to treat this, one way or another. It's not a matter of if, it's a matter of when. Nothing will stop me.

"Stem cells require a mixture of growth factors and nutrients to differentiate and develop. The medium should be changed each day." -(BMC)

The least costly potential solution to this madness just HAD to have a cancer risk, among other things. Ugh. There's always a downside.

It's amusing how 7 years ago I was complaining about tinnitus and 10 dB hearing loss, but now I'm complaining about a notch at 20 lol.

Ok. So. Standalone IGF-1 IT-injections: Very risky, despite studies of efficacy. ~100 mcg may be all I'm willing to try. Will ask doctors.

Keep hoping, searching, and fighting. An answer will be found. Maybe not today, but someday, and that someday could be here before you know.

It would really help if anyone knew a endocrinologist so that we could have an educated insight for IGF-1 safety.

IGF-1, insulin-like growth factor 1, is a growth hormone that helps regulate the human body's division of cells. It helps us grow when we are children, and contributes to our healing ability (nerves, tissue, bones, etc) and muscle growth. People that have a deficiency in it develop many issues...

If I could get $300 PRP injections for what it would require, I could probably find myself doing that in India in the near future. I'm going to get a consultation with Advanced Rejuvenation in a week or two, but I probably won't do that until next year. I'm two months away from graduating for...

My lack of time from a few months ago made me believe that BDNF wasn't in PRP, but it apparently is? That's good I guess.

It's been acting up since I stopped using LLLT. At my community college, I have a course where I have to assemble motors and another where the air conditioning is bothersome, and ever since I stopped using LLLT, my tinnitus has gotten worse and my left ear has been less tolerant. Previously I...

Fibroblast Growth Factor, BDNF, and Insulin-like Growth Factor seem to be the most discussed growth factors in stereocilia regeneration.

Fibroblast Growth Factor is another growth factor worth looking into. Unfortunately, there's no peptide version available.

If molecular, stem cell, and growth factor therapies don't work... just... what else would there be left?

Hey, are you using a hearing test app? There's a really good one called Hearing Test Pro on Google Play. It may be on the Apple Store. It actually goes to the ultra high frequencies. I plan on doing morning and night (before bed) tests every day and posting the results once a week as soon as I...

Most of what I've read online of studies on humans have been focused on sudden sensorineural hearing loss, including the PRP (which contain IGF-1). Although the results are good and promising, those are still not old injuries, so it's hard to tell. Studies on mice, on the other hand, have shown...

I must admit that the more I look into the "peptide" version, the more I am interested in trying to get that from an ENT. If the price is really around $100 for a milligram, and the cost of an IT-injection isn't tremendous, then the concept becomes really enticing. If the peptide variant is...

Why does regenerative medicine have to cost so much? Lol

Foreign standalone IGF-1 is a cancer and diabetes risk because it creates an imbalance in the system, as opposed to what is naturally produced in the body. Although 0.15 and 0.3 milligrams of IGF-1 are small, I would prefer to encourage risk minimization. IGF-1 that comes from the body is a lot...

Both chromatography and immunoaffinity purification can be used to purify IGF-1 from plasma or serum. However, immunoaffinity purification is often the preferred method for isolating low concentrations of a specific protein from a complex mixture, such as plasma. This is because the technique is...

There are moments like this where I wish I was rich. A potential answer right in front of me but it could cost so much money.

@scotty03874, after further research, I am back looking at IGF-1 now that I have learned that it can indeed be extracted from PRP. There's so many scientific publications on IGF-1 out of all the growth factors in PRP that have shown that IGF-1 standalone can induce proliferation of stereocilia...

Hey Erika, how are you? From my own research, I have learned that IGF-1 can be extracted from PRP. This would be my preferred option since IGF-1 standalone has already been shown in publications to heal cochlear damage. It's also more potent this way. I'm also now interested in exosomes and...

This Eureka feeling would be great if I had the money and time to test it out lol.

150 micrograms of standalone IGF-1 can be extracted from PRP. The safest most potent option, but it would cost more.

Well, I am glad we finally have this context. Forums can really be a huge game of telephone. I'm not going to pretend I know anything about this field, but I do know that a lot of misinformation can pile up from many posts over time. Truth can get lost in translation, especially if there's lack...