How Willing Are Doctors to Give Medication for Tinnitus?

[morgothaod]

If I simply go to a doctor and say that I have tinnitus and need medication to sleep. Do you think I'll get a lifetime supply of medication? I would like to keep taking something that'll help me sleep better and not be given a few pills and no additional refills.

 

[Danny Boy]

If I simply go to a doctor and say that I have tinnitus and need medication to sleep. Do you think I'll get a lifetime supply of medication? I would like to keep taking something that'll help me sleep better and not be given a few pills and no additional refills.

Try amitriptyline for sleep, it's pretty amazing.

"Amitriptyline acts primarily as a serotonin-norepinephrine reuptake inhibitor, with strong actions on the serotonin transporterand moderate effects on the norepinephrine transporter.[31][32] It has negligible influence on the dopamine transporter and therefore does not affect dopamine reuptake, being nearly 1,000 times weaker on it than on serotonin.[32] It is metabolised tonortriptyline—a more potent and selective norepinephrine reuptake inhibitor—which may complement its effects on norepinephrine reuptake.

Amitriptyline additionally functions as a 5-HT2A, 5-HT2C, 5-HT3, 5-HT6, 5-HT7, α1-adrenergic, H1, H2,[33] H4,[34][35] and mACh receptor antagonist, and σ1 receptor agonist.[36][37][38][39] It has also been shown to be a relatively weak NMDA receptornegative allosteric modulator at the same binding site as phencyclidine.[40] Amitriptyline inhibits sodium channels, L-type calcium channels, and Kv1.1, Kv7.2, and Kv7.3 voltage-gated potassium channels, and therefore acts as a sodium, calcium, and potassium channel blocker as well."

Interesting that it has a function on the potassium channels.

 

[Telis]

You don't want to take meds for life because of tinnitus. The meds loose their effect over time and can cause additional hearing loss and destroy your brain.

 

[truesilence]

Melatonin and camomile tea. Try some relaxation as well before bed.

 

[Harold]

hey Danny Boy. I like the Melatonin and camomlie tea over the harder reuptake meds you talk about above.

 

[Xorthian]

Do

Try amitriptyline for sleep, it's pretty amazing.

"Amitriptyline acts primarily as a serotonin-norepinephrine reuptake inhibitor, with strong actions on the serotonin transporterand moderate effects on the norepinephrine transporter.[31][32] It has negligible influence on the dopamine transporter and therefore does not affect dopamine reuptake, being nearly 1,000 times weaker on it than on serotonin.[32] It is metabolised tonortriptyline—a more potent and selective norepinephrine reuptake inhibitor—which may complement its effects on norepinephrine reuptake.

Amitriptyline additionally functions as a 5-HT2A, 5-HT2C, 5-HT3, 5-HT6, 5-HT7, α1-adrenergic, H1, H2,[33] H4,[34][35] and mACh receptor antagonist, and σ1 receptor agonist.[36][37][38][39] It has also been shown to be a relatively weak NMDA receptornegative allosteric modulator at the same binding site as phencyclidine.[40] Amitriptyline inhibits sodium channels, L-type calcium channels, and Kv1.1, Kv7.2, and Kv7.3 voltage-gated potassium channels, and therefore acts as a sodium, calcium, and potassium channel blocker as well."

Interesting that it has a function on the potassium channels.

Dont we need openers and activators? Its kv blocker so idk, if it had positive effect on t violume we would know already.

 

[Danny Boy]

Do
Dont we need openers and activators? Its kv blocker so idk, if it had positive effect on t violume we would know already.

http://www.ncbi.nlm.nih.gov/pubmed/11771024

"We investigated the effect of amitriptyline, a tricyclic antidepressant, on patients with subjective tinnitus. The study group consisted of 37 adult patients admitted to the Ear, Nose, and Throat and Audiology Department of Hacettepe University. The amitriptyline group consisted of 20 patients and the placebo group consisted of 17 patients. All of the patients were evaluated using a questionnaire, audiologic evaluation, high-frequency audiometry, impedancemetric tests, auditory brainstem response, tinnitus frequency, and loudness matching assessed by audiometric methods at the beginning and end of the study. The patients in the amitriptyline group received 50 mg/day amitriptyline in the first week and 100 mg/day for the following 5 weeks. In the placebo group, the patients received tablets consisting of lactose starch for 6 weeks, with a dosage of 1 tablet/day. The subjective complaints of the patients in the amitriptyline group decreased, and the "present" symptoms resulted in fewer complaints. The severity of tinnitus decreased in the amitriptyline group by means of subjective and audiometric methods. In the placebo group, no significant change was observed. The success of treatment was 95% in the amitriptyline group and 12% in the placebo group. Amitriptyline therapy was concluded to be effective."