OK, I Know How Crazy This Sounds: DIY AM-101 Treatment with Ketamine

[steinamo]

Regarding the AM-101 treatment, they do a intratympanic injection to get close to the inner ear. Would it be hypothetically possible to get some ketamine, dilute it in some distilled water, run that baby through a neti pot and then force the water into your tympani by gently "blowing your nose" to get the water up your e-tube and let it hang out for a while? Would there be any benefit to this seemingly stupid idea?

 

[steinamo]

And if this is so radically stupid that you don't want people seeing it I'm happy to delete it.

 

[linearb]

Well, AM-101 is actually esketamine in a gel. Ketamine vs esketamine may or may not matter, but, if you just blast some up there, it's going to be very rapidly absorbed and broken down -- AM-101's gel time releases over a more extended period.

 

[linearb]

But if you want to send me some ketamine I will be happy to try this, you know, for science :-p

 

[steinamo]

Haha, well it's worth a shot, isn't it?!?