Recent content by 100Hz

  1. 100Hz

    Topical Ambroxol and Acyclovir for Hyperacusis

    I took 30 mg pills orally, but it didn't do a lot from what I remember. I tried it topically because of a few articles I read around that time, like this, plus a few others out there: Topical Ambroxol 20% for the Treatment of Classical Trigeminal Neuralgia - A New Option? Initial Clinical Case...
  2. 100Hz

    Topical Ambroxol and Acyclovir for Hyperacusis

    Has anyone ever tried Ambroxol applied topically around the ear and trigeminal area? I tried it a few times orally when I first got some but it had no real effect, but crushing up the pill instead and mixing it with skin cream and applying directly to the areas of pain did seem to help with...
  3. 100Hz

    Round and Oval Window Reinforcement for the Treatment of Hyperacusis

    Good luck with it. Would you mind asking them the burning question about the reversibility of the surgery (in the case that it did not work, and a drug was released in the future that required a semi-permeable round window for successful diffusion), I would really appreciate it. I have seen it...
  4. 100Hz

    Pain Hyperacusis in Relation to Acoustic Shock & Synapse Disconnection

    As long I could have music and noise back in my life again and that noise was not causing me pain while listening to it (or after / delayed) then yes I'd take anything as long as it continued to work. I've tried taking benzos and some other stuff before and giving music a go but it didn't work...
  5. 100Hz

    Pain Hyperacusis in Relation to Acoustic Shock & Synapse Disconnection

    I have got some but not tried it yet because I'm not in that much pain right now, bored shitless in silence though because every time I test my ear I know I'm not going to get away with it. I don't need pain killing drugs, I need a drug that stops or disables the pain-causing mechanism. Praying...
  6. 100Hz

    Pain Hyperacusis in Relation to Acoustic Shock & Synapse Disconnection

    That's interesting @grate_biff, I always thought you had face pain with your noxacusis, and the way you describe your tinnitus is the way mine feels after a setback, screaming, but mine goes it goes hand in hand with facial and ear pain. I also hope you find something to help you one day.
  7. 100Hz

    Challenging the Current Terminology of Hyperacusis

    I don't know but my symptoms range from ear fatigue/reactive tinnitus through to setback pain which is on a different level completely. Although it's kind of a scale, it isn't gradual, there's a trigger point along the scale where a switch gets tripped and the symptoms become infinitely worse...
  8. 100Hz

    Challenging the Current Terminology of Hyperacusis

    From what Ive read I think a good theory is cochlear inflammation that stimulates the trigeminal nerve endings that are actually in the cochlea. The trigeminal nerve apparently links back to the dorsal cochlea nucleus and this fluctuating level of inflammation is what could be causing the excess...
  9. 100Hz

    QurAlis' QRA-244 — An Alternative for Retigabine (Trobalt)?

    I'm a bit hazy on this, haven't done much on it for a while but the conclusion I came to is that FX-322 could work as long as it either, a) fixed wherever rogue ATP / cytokines etc. were being released from (so if the broken ATP release site was replaced by PCA process then it would fix it but...
  10. 100Hz

    Pain Hyperacusis in Relation to Acoustic Shock & Synapse Disconnection

    I've been reading some threads from around 2015 / 16 when quite a lot of people were trial treating with Trobalt and something else called Flupirtine. They seem to be the only 2 potassium channel drugs I can find that fall under a very specific subgroup called 'Neuronal potassium channel...
  11. 100Hz

    Pain Hyperacusis in Relation to Acoustic Shock & Synapse Disconnection

    @Born To Slay, @Marin, thanks, that's very helpful. I'm hopeful for the Xen drugs as I understand they are reformulations of Trobalt. When I started looking for Tegretol but ended up with Trileptal I didn't realize they were also epilepsy drugs drugs at first, but when I found out they were I...
  12. 100Hz

    Pain Hyperacusis in Relation to Acoustic Shock & Synapse Disconnection

    Hi @Marin, I got some Trileptal recently (28 days 600 mg per day). I haven't tried it yet but I can't find anything to suggest it's something that can be taken as needed and it looks like a long term drug that needs to be increased over 4 weeks to get to recommended dose of 2400 mg. Do you know...
  13. 100Hz

    Wisdom Teeth Extraction with Hyperacusis

    Ah, yeh mine might have been a bit different. They were coming through slightly angled and were partially out but still had not quite finished but were crushing the other teeth together which is why I had to have them out. There was enough out for the dentist to get a grip of them anyway.
  14. 100Hz

    Wisdom Teeth Extraction with Hyperacusis

    @weab00, I had this done when I was your age for the same reason, all 4 wisdom teeth (no noxacusis at the time though). After the anesthetic injections there was no drilling, the guy just pulled them straight out with dental pliers (one side top and bottom first, then the other side 3 weeks later).
  15. 100Hz

    Pain Hyperacusis in Relation to Acoustic Shock & Synapse Disconnection

    Yes I think the initial instant pain is cochlear related as well because it happens in real time as noise hits and is frequency specific and then if it continues it becomes apparent that the middle ear becomes involved as 'some signal' gets relayed back to the middle ear due to the cochlea...