Recent content by Chriscom

Agreed on both points!

My tinnitus usually is a steady-state high tone. I can think of a couple other more erratic manifestations I've had that blessedly so far are quite temporary. I'd rather have at least a slightly louder steady high tone than some of the other soft erratic ones for sure.

I don't have deep knowledge here, but it's common for drug trials to work in mice and fail in humans. The two are highly similar--many successful human drugs after all have started after successful trials in mice--but the differences are enough to make it a bit of crapshoot. Very sorry for all...

Research subjects are now being recruited for this device in the Boston area (Mass., USA): https://rally.massgeneralbrigham.org/study/tinnitus_research_study You can apply to enroll on that page. From that announcement: What we are studying We are doing this research study to evaluate a new...

You've had a tough road, best of luck to you and thanks for communicating what you can, when you can.

That's a fairly significant mistake! Good to hear, thanks for sharing.

Don't worry, they're not going to shut down the trial based on one possible NDA violation. Millions of dollars spent on drug development in general and double- or gazillion-blinded studies specifically would never be risked if those investments could be sunk by one person over-sharing their...

Will you let someone else focus on what I said, and not what you imagined I said? The distinctions I'm drawing are not complicated.

To be clear, I am not saying that the preliminary, promising results of this drug were the result of a placebo effect, or that this particular NDA-breaking participant (if it's for real) is just experiencing a placebo effect. I'm saying the placebo effect is possible, and that's one reason...

If you would like to learn more about placebo effects and hearing, googling up some studies isn't difficult. Especially in relation to hearing aid trials. Here's one: Placebo effects in hearing-aid trials are reliable "Participants compared two devices that were acoustically identical, except...

Actually, they could, that's part of how the placebo effect works. And the online hearing-challenged and tinnitus community is small and connected enough for this to spread like wildfire. And there's no way to determine if this is accurate and truthful. Of course we're human beings and many who...

I had never tried this before, but I get a very slight but definite reduction in volume by clenching my jaw. Certainly not something I could do enough to help. I agree that the latest exclusion-criteria list is awfully specific across an odd group of characteristics, and that by the time the...

It's a risk but it's not automatic. I needed an MRI to rule out acoustic neuroma last year. I did some research to find one of the quieter machines in my area (major metropolitan area, so I had more choices than many), had it done (no neuroma, yay!), and escaped without any increase in my...

That's great, so thanks for looking into this and thanks to the others who learned of this and proposed it.

When I had my steroid injection to see if it would recover any of my hearing (nope), talking didn't come up--and while I might have said a word or two when they left the room, I think any extensive talking would have drawn attention to my throat and thus swallowing--I'm finding it hard not to...