Recent content by JK888

I don’t recommend that you do any of those “treatments” I mentioned in previous posts alone.

It can be both. This study indicates that it is due to inflammation: https://news.arizona.edu/story/brain-inflammation-identified-potential-target-treat-tinnitus

Most people grow it themselves. This is a course on how.

It is insanely expensive, and unlikely to have an effect on neuroinflammation unless injected directly in the spine. It doesn't cross the blood brain barrier otherwise. Psilocybin does block TNFa and crosses the blood brain barrier and it is practically free.

Yes. MUCH safer. Overusing steroids can lead to bone death, particularly the leg bones. I know someone who got desperate to make their cluster headaches stop, and overused steroids. They had to have double hip replacements. With Psilocybin, there is no physical risk anywhere close to that. I...

Truffles are very weak in comparison to mushrooms, so you would have to eat a lot more each time to get the same effect. Per gram, mushrooms contain roughly 10 times more Psilocybin than truffles. It will be cheaper to grow it for yourself in these quantities. I wouldn’t start the process...

Control The Experience. I suggest you focus on learning cues and techniques for managing the trip. Learn some “rescue” techniques on what to do if you become uncomfortable. Don’t forget that there are “rescue techniques”. With the use of VR headsets as one of the redirecting tools, the...

I stand corrected. I assumed that the term just meant reacted to sound in general.

I was a guinea pig for the Psilocybin part, but not exactly microdosing. Psilocybin Stopped the Ringing in My Ears

I think that they will have great results. The effects of 5ht2a agonism and inflammation are well documented. They can look at dozens of different inflammatory diseases, the mechanism is the same. Antioxidants? Sure. They are good for you. Destress, eat healthy, yadda yadda. But taking some...

I did something like this under the influence of psilocybin, and it was EXTREMELY effective. After my attention wandered, I eventually couldn’t even find the sound again.

Steroids are effective, but they cannot be used long term. Even using Psilocybin requires regular dosing. If I had been using steroids at this frequency over the past year, I would be due for a double hip replacement.

Be careful about jumping to conclusions about anything regarding plasma levels. TONS of medications can reduce TNF in plasma. That is just blood. The tissue they need to target can technically only be tested upon autopsy. Maybe a spinal tap could give some info, but it wouldn’t be necessarily...

Did you read the article I posted above about neurodegenerative disease and TNFa? Between that and the one about Enbrel, it should be pretty clear that we are not talking about inflammation limited to blood vessels.

This paper does a good job of explaining why biologics don't help neuroinflammation: Neuroinflammation as a Common Feature of Neurodegenerative Disorders Keep in mind that it is old, FYI. I'm not sure what happened with the new interest in Thalidomide.