Recent content by serendipity1996

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    Otonomy OTO-313 — Treatment of Tinnitus

    Frequency are not using notch therapy - they are doing Progenitor Cell Activation. Completely different things.
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    Xenon Pharmaceuticals' XEN1101 — Kv7 Potassium Channel Modulator

    We also have anecdotes from people on this site that the old Retigabine (Trobalt) helped their noxacusis.
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    Frequency Therapeutics — Hearing Loss Regeneration

    Exactly - I think Retigabine could definitely provide symptomatic relief but at the end of the day it's not a curative drug or repairing the underlying structural damage that has led people to develop tinnitus. It will also probably come with side effects even though it's been made safer. It's...
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    Road to Recovery from Loudness and Pain Hyperacusis (Noxacusis)

    Right but earplugs aren't really "sound deprivation." Most musician's plugs and even most foam plugs are only reducing and taking the edge off - hardly like you're in a sound isolation booth.
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    Frequency Therapeutics — Hearing Loss Regeneration

    This is not the case and has been known for a decade - Robert Jackler from the Stanford Initiative to cure hearing loss mentioned that regrown hair cells come with intact synaptic connections that link up with it and called it a 'miracle'. Also, Frequency's own studies have shown that...
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    My Hyperacusis Is Cured & I Barely Have Tinnitus Anymore

    It's always good to hear recovery stories but head's up everyone - DXM is not classed as a psychedelic drug, it is in fact a dissociative (e.g., Ketamine is a dissociative but not a psychedelic). This should be corrected or made clear.
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    Frequency Therapeutics — Hearing Loss Regeneration

    I mean, I don't think it's just some lone tiny minority of people on this thread who believe in this theory, as you seem to think. This is hardly a fringe opinion either. The Hearing Health Foundation last year made a post about how treatment of noise-induced tinnitus will require developing...
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    RL648_81: Synthesis and Evaluation of Potent KCNQ2/3-specific Channel Activators

    Most of the discussion has been on Xenon Pharmaceuticals, which has developed a reformulated version of Retigabine with improved potency, safety, and selectivity. They already have two drug candidates in Phase 2b and Phase 3 of clinical trials.
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    Episode 17: Tinnitus, Ingrained in the Brain? — Prof. Dirk De Ridder

    I think it's worth noting that last year the Hearing Health Foundation, one of the most prominent organisations in this space, published a post stating that curing noise-induced tinnitus "will first require curing hearing loss"...
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    Hyperacusis Has Subsided

    No, my first experience of hyperacusis was late 2016 which went away after a few months. I then had a major setback/relapse at the end of 2019 and it's taken the last 18 months to recover from it - I had 24/7 burning ear pain for 3 months but lingering facial neuralgia and sensitivity for a long...
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    Hyperacusis Has Subsided

    It was related to my acoustic trauma and has lessened over time as my hyperacusis has improved. I don't have it any more.
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    Frequency Therapeutics — Hearing Loss Regeneration

    There are closed captions.
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    Share Your Coronavirus (COVID-19) Vaccine Experience: Any Impact on Your Tinnitus or Hyperacusis?

    Got my 1st Moderna vaccine this morning - only side effect thus far has been a sore and stiff arm. No effect on tinnitus or hyperacusis.
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    Frequency Therapeutics — Hearing Loss Regeneration

    You did mean this as a joke, right?