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http://www.dailymail.co.uk/health/article-2956195/Pill-stop-hearing-loss-tinnitus-tested.html#ixzz3S6PV22Vi

Thanks for the effort. Do you know if you have to be a resident of Germany, Austria or Uk in order to participate in the study?

This is the power of the double blind placebo study. They give the drug to one group of people and a placebo drug to another group. Neither of the groups know what they got (double blind). Then they have to find the difference in cure rate (here probably som kind of reduction parameter) between...

All right. What a heated debate. I don't like the vibe! Here are my two cents: Yes, Dr. Wilden's 'scientific' explanations are a bit lame. Is he a quack? Well, some people seem to have had positive effect of his treatments. Does this mean that his treatment would pass a double-blind placebo...

Hi Tenna, The mind is a powerful tool. Indeed. I, too, believe that in order to succeed in any tinnitus treatment you must believe in it. This (Iben & Mødregruppen 15-02-2013 (2) / Ibens – Radio24syv) is also on tinnitus (Danish). A woman, who's husband had tinnitus, explains how he imagined...

Yes it does. You think that Swedish guy You wrote to could be a scammer?

That must be a fantastic sensation to have silence. Can you describe it?

I have a bunch. Had them since I was a child. Never got worse. Hardly ever notice them anymore. Don't annoy me at all. I find them funny to play with sometimes.

Come on researchers! Hurry up!

Really! I never thought about heaven as a quiet place before I got T. But if I am going to have an afterlife, it better be quiet! Yesterday I read about a guy who has been in solitary confinement for 28 years. One of the things he described was about the lamps in his cell that buzzed: ' In...

'This device delivers mild electrical pulses to the nerve endings in the tongue. mutebutton is intended to be used for at least 20 mins per day and over the course of weeks and months, has been clinically shown to significantly reduce the loudness of the tinnitus sound and the associated...

Early 2014 - that's very soon. The 'button' part sounds a bit like the 'tap the backside of your skull'-tricks. I wonder if it's meant for permanent suppresion or temporary relief. Edit: Oh, I can just use their website. The Device | mutebutton is an innovative new tinnitus treatment that...

Indeed it does. I can't believe that only 300 researchers worldwide are working on research in an area that affects so many people. I think too many tinnitus associations (etc.) believe too much in habituation - not that I don't believe in it, not that it's not a great thing that one can...

With all the respect for The Tinnitus Clinic (www.thetinnitusclinic.co.uk), this is a good example on why it would be good to have a researcher answer questions. I could provide other resources telling you another story.

http://clinicaltrials.gov/ct2/show/NCT01934010?term=tinnitus&recr=Open&rank=22 This is the next trial. They only take people who also participated in the previous trial.

Dear Ken, I am so sorry to read about your situation. You can always find support on this forum! You need to get some sleep. All doctors know that this is very important. If Lorazepam helps you sleep, then you allready found something in that regard. Insist on getting the medication. Be...

@Markku, have you ever tried contacting some of the prominent tinnitus researchers and asked them if they would like to do a Q&A / AMA session here on Tinnitus Talk? It would be nice to have an expert confirm/deny many of the theories floating around this site. Mainly, maybe, in terms of...

If you mean 'sensorineural', then it refers to tinnitus caused by a sensorineural hearing loss, hearing loss due to damage to the inner ear (loss of inner hars cells, that transforms vibrations to neural activity (sound) in the brain)

I am wondering... If we accept the hypothesis that T is the brain adjusting to missing input on certain frequencies, and if we assume that the hearing loss is not total, then could a perfectly fitted hearing aid not do the same as repairing the inner ear?

Hi Anne, You can't protect yourself from accidents. It is not your fault. Wait and see - the ringing will probably subside. Hopefully.

To me, the first step is to accept that it's a fight that cannot be won overnight. I keep listening for the fast way out - that the T dissolves by itself. After, now, almost 5 months, I am slowly (!) accepting that this is not going to happen, so I have decided to start the fight. MY first goal...

I wish I knew that too. There are two kinds of low: One that feels like my brian is taking away the focus from it. And another one that feels more like the actual sound is low. The last one is so much nicer, but totally random. In both cases, I can still hear it, though.

Yes. A lot. There's nothing constant in my T. Yes, maybe the low-volume pure tones, that I hear underneath 'it all'. Sometimes my T is almost non-existant. Sometimes it's the loudest. Sometimes it's a sharp tone, sometimes it's noise as you describe. Fluctuating up and down in pitch with...

I can't believe why ENTs do not take this more seriously. They must have had numerous of people coming through with T. Many of those people must have been very distressed. I just don't get it. I don't know what they imagine? A soft little pure tone only audible at nighttime? Well, i have that...

I was told about a study done in Germany, where T patients had the T loudness matched (as I recall it was done by masking level) on different days. Some days they reported their T to be loud, somedays the opposite. The study apparently showed that the masking volume was the same everyday. It's...

@JTP: Oh, yes, I am aware of that. The latest audiogram I had was up to 12,5 kHz . 8kHz and 12,5kHz was 0 dBHL. I have dips down to -10dBHL up to 6 kHz. Haven't had my audiogram done for higher frequencies, but I can hear pure tones up to 17,5 kHz without boosting the volume too much

No, I don't have hyperacusis. My tinnitus is super fluctuating. Both in form and volume. And very high pitched >15kHz when it presents itself in the pure tone form. Edit: Thanks for the explanation, jazz.

@Jake I hope you're right. I really do.

Well, if this ends up working, I actually don't care if I should wait a little bit. Two reasons: 1. The sole fact that knowing a treatment is available makes tinnitus much less annoying. For me, the hard part is the incurable part. 2. They can improve the implementation while testing on the...

That's what I heard about the cortisone as well. For sudden deafness.

What I have heard about cortisone injections is that sometimes it helps if it's injected within the first few days of onset. And the scientific community doesn't even agree on that. Never heard about the acid, though.

Call them on behalf of this community. Try to get some results. Some trials they have done. That would be highly appreciated.

constant? always sounding the same?

Dear dmhead, Sorry to hear about your tinnitus. Hopefully it is TMJ and can be corrected. To this, I am a bit curious - how does your tinnitus sound?

How does your T sound?

Dear TinnitusTalk, I am wondering if any of you experience this (or maybe has some kind of explanation): If I am masking my T with white noise, the T is louder and sharper in pitch when I turn off the noise. Significantly. I am playing the noise through laptop speakers at a low level.

@Owch. Yes, it's indeed within the margin of error. Especially since the hearing tests are normally done with 5dB-steps. There is also an effect of training. But as you say, there is a consistent overperformance, which is a good sign. And the subjective feeling you had during the audiograms also...

Oh. Was it 'such an organisation'. I raed it al worng, then. But anyway, c'mon researchers! I still believe this to be one of the most well-paved roads to a tinnitus cure for a large variety of cases.

I remember him mentioning that he had spoken to some kind of organisation, that recommended this clinic - I just can't find the quote. Am I wrong?

I have been in contact with the clinic and they claim to have treated 3 people with very good results. They even gave me a telephone number to a guy I could call, who would tell me of his experince - it is a bit suspicious, though, that this guy is 'currently in Bangkok'... I have asked them...

I had an email correspondance with Karl Koehler (http://news.medicine.iu.edu/releases/2013/07/hashino-stem-cells-inner-ear.shtml) and asked him 'Does IV injections with human cord blood stem cells have a chance to repair damages on the human cochlea?' - this is the treatment @attheedgeofscience...

Could you try to sneak in some stem cell questions? :-) 1. Do you think that IV injections with human cord blood stem cells have a chance to repair damages on the human cochlea? 2. Would there be a way to optimize the chances in this kind of treatment ie. different approaches, supporting...

Very touching. I can't comprehend how wonderful an experience that must be. She has a very good language for a born deaf person? Actually, there has been sensorineurally deaf people reporting that their tinnitus dissappeared after turning on the cochlear implant. And then staying away several...

I get this warm fuzzy feeling inside - if I could record this fuzzyness it would probably mask my T - when you say 'sooner than later' :thankyousign:

Let me try and explain, what I think might be the explanation: The high pitched T is hard to mask as not many other daily sounds has a very high pitch. The reason you are hearing it all day is probably because of that rather than it's volume itself. Then at evening you have another tinnitus...

That's batshit crazy! I would suspect people without tinnitus to be at a much higher risk? Also getting T for a musician for the first time is more likely to have him cancel the tour than an eventual increase?

@seal I get your point (though I would think that it was Liam making fun of Noel.) But all the 'don't be such a baby about it' is probably a good way to handle it for many people, since there is no cure. But I doubt that any musician wouldn't have the ear fixed if it was a possibility. The...

Yeah, well, it might seem a bit overoptimistic, but if a cure for this disease (or symptom as experts prefer to call it) is to be found we must push all the buttons. Furthermore we must try all options. Stem cell treatment might not (?) be at the point yet where it can totally restore anything...

Yes. And since its from the umbilical cord, otherwise thrown in the trash, the ethical issues are few.

From https://www.researchgate.net/publication/257646859_Tinnitus_therapeutic_use_of_superficial_brain_stimulation?ev=contentfeed: ABSTRACT (...) Single sessions of rTMS over the temporal or temporoparietal cortex have been successful in transiently reducing tinnitus perception. Repeated...

A few more links I have stumbled upon recently. I have mainly focused on umbilical cord blood stem cells, since those apparently are the most potent ones and treatments injecting these intravenously are already available. http://www.ncbi.nlm.nih.gov/pubmed/20871652 Umbilical cord blood stem...

Oh, actually Erlend and I are doing this at the moment. Everytime we stumble upon a stem cell article we email the authors and ask them if the current state of stem cell technology could have any real possibility of providing any improvement in the inner ear. So far none has responded. Eventual...

Dear sword&shield! One of my best friends is a professional jazz musician and after having tinnitus for 15 years he now plays in big bands without earplugs. His tinnitus has not worsened. It does not bother him anymore. He can't remember pure silence. I can't fathom this myself, but as he said...

I just wanted to agree on this part, especially.

This is physics due to 3 factors. I suspect this phenomenon only exists for high frequencies. 1. The interference pattern for high frequency pure tones has very short distance between the minimum and maxiumum points. This means that if you move your head (side to side) you will notice pressure...

Hmm... Googling 'LY41175' gives results, where you can buy the chemical. On 'http://xcessbio.com/index.php/small-molecules/ly411575.html' they actually tells you the oral dose they gave the mice in the experiment. I am aware, that it would be stupid to experiment with the drug, but it's...

If this guy has promising results I am very excited. Reading the top result on Google (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297194/) has convinced me that he is not just hocus-pocus. He seems to consider the big picture in that article. I would just very much like to know if his testing...

Well, this is going to be speculations, but I see the treatment divided into two separate steps: Step 1: Treat the underlying cause of the tinnitus. For the cases where this is cochlear damage (noise, ototoxicity etc.) stem cells will probably be the key. Many people throw around the number 10...

Current IRB stipulations require more detailed updates. Not related to current patient safety or non-compliance issues. I suppose IRB is some kind of review board that accepts the trials. This trial, apparently, needs more 'details'. What these details are, we don't know (besides from what's...

http://www.cellcare.com.au/latest-research/another-research-item Human testing on restoring hearing with cord blood stem cells! ...and http://www.multivu.com/mnr/53686-cord-blood-childrens-memorial-hermann-fda-approved-stem-cells-hearing-loss Edit: Apparently this is old news (2012) - it...