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Using a combination of 3-D printing and cultured cells, scientists in China have grown new ears for five children born with a defect in one ear called microtia, which impacts the shape and function of the ear. In a first-of-its-kind study, researchers describe how they collected cartilage cells...

so what happens with people who have both synapse damage and hair cell damage? Do they need both medical approaches in theory by decibel and FX? How do we even know what type of damage a HUMAN has? Where are the imaging devices because at the moment a hearing test seems vastly, VASTLY outdated...

What are your guys thoughts on FX approach towards Hyperacusis caused by noise exposure? Love some discussion around this

so what happens if you get this procedure and then damage your hair cells again? Proper fucked and nothing can help you? Lol

I don't know if I am the only one but this is the drug I am really excited about as opposed to Frequency Therapeutics' approach. They're actually REPAIRING the broken auditory nerves and it looks like the medication was induced orally through animal models. Very excited about their approach!

sorry i was a little unclear, I am meaning that those dead hair cells are still making noise/brain stimulus is filling the gaps of missing frequencies. Their approach is creating new hair cells, but the old ones are still going to be there. Won't the dead ones still be firing away regardless of...

They die? Well even after a year they seem alive and well because they're fucking ringing like crazy still to this day haha. I just understand how this works.... like the hair cells will repsond to sound regardless of if you want them to or not, like the sound waves will still hit those...

Does anyone have any idea what happens with the damaged hair cells with frequency's approach? I understand they are using progenitor cells (whatever that means) but what about the ones that are actually damaged? Will they remain damaged and then will there be new hair cells next to them? How do...

The hair cells or ribbon synapse. Either one is the broken input that is causing the ringing . The brain obviously has a role in this because the brain controls literally everything in our body. But, the brain responds to input. Without the input or broken input there normal functionality

it's not 2-3 years away, you keep spreading false things on this forum. Nobody knows, you dont know better than clinical researchers either so no idea why you think you do. Only truth is that they are somewhat closer than they were a few years ago as their understanding increases. Stefan Heller...

can you provide references to published studies where the brain says it can't unlearn T? Reading this sort of stuff is highly annoying. The brain responds to input, i.e a pinching in your arm is registered in the brain as pain. Remove the input the pain will go. aka fix the cells causing...

AM-101 is done and dusted I feel. Forget it and go live your life and put your faith into regenerative medicine which is probably 20 years away before some of it hits the market. It sucks yes, but there's not really much else we can do.

It got me thinking lately. I still think it's somewhat 20 years away but who knows haha

holy shit, currently going through it and there's so much stuff. Him in r/startups asking what he should call frequency tx before it even had a name and there's photos of stem cells he's created and uploaded that look like a penis from years back (hahahaha). great find! it's a gold mine of his...

is a dip at 3k an indication as well? just seems weird as it's only in one ear and the only loud noise came from headphones.

there's my audiogram. kinda weird how i have a sharp dip in 1 ear only when im 99% sure mine was caused by headphones

anyone else hear have noticeable hearing loss but has no trouble hearing in loud noises? for example my music sounds different and i have t and h but i hear my friends fine in busy restaurants and when there's plenty of backgound noise. Goes to show how far behind this field of work has been...

headphones but i was also on 200mg of doxycycline a day for 6 weeks straight for a sinus infection. But i did listen to loud headphones during that time as well. it could have been a the headphones, the doxy or a combination of both. who knows, but i really think it was the headphones sadly...

the last paragraph you respond to about it not working in humans, what is that paper/where did you source it from? cheers!

i have hearing loss just haven't updated. I notice a difference in my music now and i have pain. Feel free to pm for my audiograms

and this is why you should never consult the internet for medical opinions. Some of the worst advice i've read in awhile. So many wrong things about this post that I want to tear to shreds but I just feel like its's a waste of time with people who have no idea what they're talking about in the...

50+ years from what, a cure of tinnitus or heairng loss? they'll figure out hearing loss before tinnitus. You can't even give a timeframe because neither do you or medical experts know. I'll go out on a limb and say that they'll figure out how to restore hearing loss before fixing tinnitus (even...

great, but we want a proper biological/neurological fix to hearing loss and Tinnitus. Wish these studies wouldn't even happen, you don't need to do a study to come to the conclusion that meditation and mindfullness helps with stress and health problems. Complete waste of time on their behalf!

Part of me wonders if the delay is because they want to try the much more advanced Anc80 viral vector that was only broken to the public in January (which was a harvard discovery). in short the "supercharged" aav that is wrapped in bubbles instead and has far superior results. Who knows, could...

you keep posting links that have already been dicussed. Please don't post anything at all before looking in the forums. it's highly f****** annoying

Was about to say this as well. Thank you. Samir take the hearing aid talk elsewhere!

When they say phase 1/2 trial do they mean they're in phase 1 AND 2 or Phase 1 OF 2?

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0051915 < here's a study in regards to hearing aids and T. It's pretty obvious Tinnitus is caused by loss of sensory hair cells/synapses. I don't see how it's not, I never had T or H 6 months ago and now I have noticeable hearing...

Nope hasn't improved and don't see it improving until they know how to restore hearing biologically! I'm use to it now more I guess, like when i go to the city I just expect the loud brakes but my reaction is a lot better I believe. Whilst T and H is a bitch it's manageable don't ever forget...

I take 10mg of amitriptyline a night ( basically the same) and it helps me sleep and stay asleep. It's helped me massively. It made my T jump for a like 4-5 days then went back down and has kept it somewhat normal. It won't increase your T for good so don't freak. It takes about 2 weeks for...

i experience exactly this. Bass sounds tinny or like a tamperin instrument. I read your post about super hearing Lex from a few weeks/months back in regards to car brakes...i also have this. I can pick up the screeching from a mile away. That and basically anything squeaky

Those of you with hearing loss, does music sound different or not as good anymore to you?

I know we shouldn't expect much from the novartis trial but if it comes back that a handful of people have seen some improvement then this is massive news. It's massive because it shows that 1) they can successfully reach the cochlea and 2) the gene identified for hair cell regeneration plays a...

when do you think we will see this being used in human studies?

so my question......do the old hair cells/dead synapses remain when they regenerate the supporting cells? Or when they mean regeneration they mean regenerating in the EXACT place where the damage has occured (meaning that they still fire away causing T/H)

I have a question guys, when they talk about regenerating the hair cells within our ears and using supporting cells, does this mean that the old dead hair cells will remain? From what i am aware they want to use "progenitor supporting cells (frequency TX) " but this hints at regenerating hair...

@stophiss here are my hearing test results. The first one is 2 weeks ago and the second image is my results from yesterday. The audio sad that my tests were basically the same even tho there was a slight dip in 5db in my left ear. She acknowledged that this was a margin of error and could...

yeah bro, mine can be a bit like that as well. the most annoying thing is the sound distortion i have and hearing loss i.e. my music sounds different because i cant pick up the certain sounds anymore. it sounds like a bit of a mess. The T isn't so bad after awhile it's just like there which...

Honestly, just ignore it. You can't go about life being scared of loud noises. I've had T for a month and encountered a lot of loud sound in my day to day life in the city - buses that have air breaks, car horns, metal/steal being dropped etc the lot. You'll make yourself paranoid about sound...

^^ as title.

@stophiss fantastic response! I never thought of it that way but you make very valid points that could very well be correct. I have my second audio test tomorrow so i will update you on her thoughts with my T and H and see if she can give any of her thoughts. Once again great reply!

About a month leading up to the full onset of ringing

hey man i am the exact same as you! The bass sounds like a blowing speaker but i have no probs hearing higher frequency, although my ringing is how pitched? I get a low tone sometimes but its not very often so i am very confused as well

Hey there. I love music and it's sadly given me tinnitus. The biggest issue is that music just sounds out of tune due to hearing damage where i can't pick up certain frequencies. Are there hearing aids that help mask the tinnitus and make music more enjoyable again (at low volumes of course)

and i think it's given me tinnitus and hearing loss :( anyone else had this? The internet is conflicted

i found the noise of fans, nature, waves a little too much but crickets seem to be really really soothing. it's 10 hours long as well!

If we were told we were terminally ill T would most likely become the least of our worries So keep smiling beautiful people I know its hard but we can do it :)

I will update you lot in the coming week to see how I get along. It is not tapered it's just 60mg Prednisone straight for 10 days from the doctor

Stay safe and kick T's ass by living an awesome life as much as you can. Do something out of your comfort zone! Life is too short to be sad regardless of the situation. We can walk, we can run and we can see. We are not in wheelchairs. We are not terminally ill. We just have this annoying...

just to add I had a beer (330ml) about 3 hours ago and i don't know if it's just a massive coincidence or the beer drastically reduces my T? it's like a 0.1/10 and its not even a ringing, it's the sound of crickets.

what the hell? it's noise induced as well and expecting it to come back any second but i am highly confused? I've had it for 3 weeks

Hey there, T recently started for me around 3 weeks ago in my left ear and I recall it around the time I got neil-med sinus rinse water in my ears. I also listen to loud music, but i had a hearing test and it showed a dip in my hearing in my left by about 13db in a certain frequency. I'm quite...

Here are my results. I have noticed the onset of tinnitus in my left ear the last couple of weeks, with it going into the right on occasion. Have been on doxycycline the last 5 weeks for a sinus infection so not sure if it is related, but my GP said that doxy is not ototoxic. The Audiologist...

I've had tinnitus for about 10 days now and music sounds weird. I have a very clicky jaw and pain in the TMD joints and I grind my teeth. Is there any way that my jaw could influence the way I INTERPRET sound?

I have only had tinnitus for about a week but my jaw is clicking like crazy and when I push my lower jaw forward it's making like a grinding/cracking sound in my ears that is very loud with immense pain?

Hello guys, so I recently developed Tinnitus ontop of my chronic sinus issues i've been battling for nearly 6 months! (I know sucks :( ) Anyway, I did a bit of research and I came across TMD/TMJ. Anyway for 2-3 weeks I complained to my doctor that i could hear mild ringer in my ear, and...