Acamprosate (Campral)

I am very curious about Acamprosate because it suppresses the glutamate receptor neurons, which is exactly what happens when you get drunk. My tinnitus DISAPPEARS when I drink copious mount of red wine. As I am drinking to relieve my tinnitus, I am hoping that the glutamate suppression effect from the drug will do the trick for my tinnitus.
 
I am very curious about Acamprosate because it suppresses the glutamate receptor neurons, which is exactly what happens when you get drunk. My tinnitus DISAPPEARS when I drink copious mount of red wine. As I am drinking to relieve my tinnitus, I am hoping that the glutamate suppression effect from the drug will do the trick for my tinnitus.
My consciousness disappears when I drink copious amounts of red wine. This makes every ailment I have disappear! Of course, they all come back when I wake up, along with a hangover...

Anyway, one week into trying Acamprosate and so far no noticeable change. If anything, it has made it subjectively worse. Very disappointing.
 
Another study on Acamprosate was conducted a few years ago, with positive results. It seems to work better in those who have had tinnitus for a shorter duration & sensorineural tinnitus, i.e., perceived in the ear/hearing loss-related.

I'm sure some here would benefit. I'm keen to give it a go.

Impact of Acamprosate on Chronic Tinnitus: A Randomized-Controlled Trial

Someone posted this on another thread:
I have high frequency tinnitus white noise ("hiss") in both ears I wear hearing aids and have had tinnitus for over a decade, but it got bad after falling asleep with rain sounds EQ'd to compensate for my hearing loss. It sounded "real" and seemed like a good idea. I woke up to a symphony of screaming tinnitus in both ears. One year later it had gone down quite a bit, and I went to sleep with my hearing aids in place next to a new but noisy Frigidaire air conditioner. I woke up from that with increased tinnitus in both ears and a new, lower pitched tone in my right ear (which was 3 feet from the A/C). I can live with the hiss (which has lessened), but the lower tone in my right ear is what bedevils me. My particular tinnitus, BTW, is much worse when I wake up from sleeping.

I am taking: Acamprosate (666 mg 3 times a day), Sulodexide (1 oral capsule twice a day), Luteolin and Rutin (100 mg each twice a day), Ginkgo Biloba (120 mg twice a day), CoQ10 (200 mg once a day), and Melatonin (3 mg once a day).

All the above except for the Acamprosate I've been taking for over 6 months. All of them seem to help, but the biggest change has been since taking Acamprosate 2 months ago and, in the last week, please do not laugh, Sake wine. Sake helps. Not drunk, but slightly buzzed. But that is on top of the Acamprosate, which was helping a good deal on its own. As for the Sake on its own, I wouldn't know I drink Gekkeikan Sake (which is the cheap stuff). Before, every night, I drank 100% Agave Tequila in moderate quantity, but when I overdid it, the tinnitus would get worse. Regular wine (white or red) seemed to always make my tinnitus worse. But Sake is different. The effect of the Acamprosate BTW has been very gradual. My plan is to go 6 months and see where it leaves me. But I started drinking Sake just for old times sake after seeing it in the market, and I noticed a rather abrupt and significant reduction of the lower right ear tone.

So, I'm happy with it, and FWIW, I wanted to pass it on.
 
I took Campral for a week but developed a terrible rash on my chest and stomach, so I stopped taking it. After I discontinued the medication, the rash went away. It has now been about three months.

I was advised to try Klonopin (Clonazepam) to see if it affects my tinnitus, but I am hesitant to do so.
 

Log in or register to get the full forum benefits!

Register

Register on Tinnitus Talk for free!

Register Now