AM-101 Was My Savior

[ahs]

When I enrolled into the am101 trial that I had heard about on here I promised myself I would update everyone on my results. At the beginning of the trial my tinnitus was I felt 8/10 and some days 9/10. After the injections my tinnitus quickly improved and at the 2 week mark I was consistently at 2/10 and many days 1/10. The positive results have remained. Right now I'm at about 1/10. It doesn't noticeably fluctuate. I was about 2 months into tinnitus when the injections were given. If anything changes for me I will make another update. I hope others attain similar results.

 

[monacco]

@ahs
How did you know that you have received the real drug ? may be it was just a natural reduction

 

[JohnK]

How did your tinnitus come about?

 

[elizabethab]

When I enrolled into the am101 trial that I had heard about on here I promised myself I would update everyone on my results. At the beginning of the trial my tinnitus was I felt 8/10 and some days 9/10. After the injections my tinnitus quickly improved and at the 2 week mark I was consistently at 2/10 and many days 1/10. The positive results have remained. Right now I'm at about 1/10. It doesn't noticeably fluctuate. I was about 2 months into tinnitus when the injections were given. If anything changes for me I will make another update. I hope others attain similar results.

How did you sign up for this? I am barely 2 months in-have been told it has to be within the first three months...I am in North Carolina....

 

[marqualler]

How did you sign up for this?

Start here:

http://tinnitus-study.info/

 

[LadyDi]

Awesome, @ahs. One can assume it was the drug -- although there is no way to ever completely know for sure. Regardless, it's great to get an update and to hear you are doing so much better.

 

[liquefact]

Can you describe the after-injections process please? Did the loudness of your T increase after injections? How long it took to go to the baseline? When did you start feeling the improvement?

Thanks.

 

[Nucleo]

Can you describe the after-injections process please? Did the loudness of your T increase after injections? How long it took to go to the baseline? When did you start feeling the improvement?

Thanks.

To my knowledge, this is the most up-to-date info on AM-101: https://www.tinnitustalk.com/thread...dates-and-discussion.6558/page-20#post-119473

You shouldn't expect improvement until several weeks in.

 

[liquefact]

Yeah, know that thread. Still wanted to hear @ahs 's personal experience. Glad to see that we have one more data point proving it works.

 

[Cheza]

@ahs That's great news and gives reason for hope, especially for those with acute tinnitus. I hope the reduction is permanent.

 

[Ecip]

Yes, if this works for acute tinnitus (not the acoustic shock kind, don't really know why I have tinnitus) then I'll be getting me some of that.
And if it works for people who had years of T then maybe I'll send my old man that way too! He really screwed his ears in a tunnel explosion.

 

[Nucleo]

Yes, if this works for acute tinnitus (not the acoustic shock kind, don't really know why I have tinnitus) then I'll be getting me some of that.

AM-101 is actually targeted at acute tinnitus caused by a traumatic event (acoustic injury, barotrauma, middle ear infection). They are recording patient history (I hope so at least). I guess we will have the breakdown of efficacy vs. tinnitus etiology.

 

[Ecip]

If this works, that would be a great breakthrough.

 

[Richard zurowski]

Wouldn't this drug only benefit people with short term tinnitus and not long term tinnitus?

 

[Keith D Mitchell]

Wouldn't this drug only benefit people with short term tinnitus and not long term tinnitus?

I'm actually in talks regarding the trial now and what I was told is they are only accepting people that meet the two requirements;

1. Have had tinnitus for less than 3 months
2. Tinnitus was due to an infection and not by loud noise.

It may be different depending on the study/who's running it, but that's exactly what I was told.

Luckily for me, I meet both of those requirements, so we'll see if I get accepted or not.

 

[Markku]

I'm actually in talks regarding the trial now and what I was told is they are only accepting people that meet the two requirements;

1. Have had tinnitus for less than 3 months
2. Tinnitus was due to an infection and not by loud noise.

It may be different depending on the study/who's running it, but that's exactly what I was told.

Luckily for me, I meet both of those requirements, so we'll see if I get accepted or not.

People whose tinnitus was triggered by loud noise not accepted? As far as I know, that's incorrect information. I wonder if there was a miscommunication / misinformation? Can you double confirm with the study center?

US AM-101 Phase 3 Trial:

UK AM-101 Phase 3 Trial:

 

[Keith D Mitchell]

People whose tinnitus was triggered by loud noise not accepted? As far as I know, that's incorrect information. I wonder if there was a miscommunication / misinformation? Can you double confirm with the study center?

I'm still waiting to hear back, likely won't get an answer until next week, but I remember the persons exactly words regarding this. As this was my second time talking to them, the first time she flat out denied me as I didn't know the cause of the ringing. That changed once I said it was confirmed as an middle ear infection, course of treatment and my hearing charts.

 

[JohnK]

What sorts of questions do they ask your when you go in for a pre trial evaluation? Anybody with experience in this?

 

[TJohns]

Where are all these am101 people who are a year out ? Do they just stop coming to TT ?

 

[Bobby B]

I saw that a lot of them switched over to the
SilenceTalk.com forum

Check it out, some of the posts are pretty depressing :

"Can't take it anymore - this silence is killing me"

"Woke up to the sound of my heartbeat ! Please help"

"Neighbour's cat drives me crazy with the noise of walking over the grass all day"

And a real eye opener :

"Miss the good old days waking up with my tinnitus - do you think that going to 5 ac/dc concerts in a row standing at 2cm from the speakers will help getting my life back ?"

 

[TJohns]

Yea that does suck
Hope to switch over one day myself

 

[Zora]

@Bobby B ?!?! Da fuq? I cant believe that. i'd be soo happy? I mean...silence thats all we want dont we? Sorry but I dont understand....

 

[Zora]

@Bobby B could you give me a link? i couldnt find Silencetalk.com

 

[ceauses97]

@Bobby B ?!?! Da fuq? I cant believe that. i'd be soo happy? I mean...silence thats all we want dont we? Sorry but I dont understand....

He was being ironic. Women....

 

[Sebastians]

*facepalm*

 

[Zora]

haha....you must be so cool....I read it very quickly, and btw there actually are
people who are saying that if their T wouuld leave them, tgey would feel like something is missing.

 

[RaZaH]

Indeed , when I get the occasional silence (while on trobalt) I truly find that something is missing , super weird!

 

[trocobob]

Indeed , when I get the occasional silence (while on trobalt) I truly find that something is missing , super weird!

lol , the same for me ...seems like this is the effect of habituation

 

[Alue]

I saw that a lot of them switched over to the
SilenceTalk.com forum
Check it out, some of the posts are pretty depressing :

"Neighbour's cat drives me crazy with the noise of walking over the grass all day"

To be honest that sounds like some severe hyperacusis.