An Update: Emerging Drugs for Tinnitus

[Daniel Lion]

Currently compiling a list for emerging tinnitus treatments. So far I have the following:

For tinnitus directly:
OTO-313 (Otonomy)
XEN1101 (potentially)
Lenire
University of Michigan Device
University of Minnesota Device
Visual Snow Device (maybe, potentially? awaiting more information from visual snow initiative on what this is about)

Hearing loss restoration:
FX-322 (Frequency)
CGF-166 (Genvec/Novartis)
LY3056480 (Audion/Regain)
OTO-6XX (Otonomy, further into the future)

Hidden hearing loss:
OTO-413

Potential treatments in the very far future:
Refined deep brain stimulation (what Neuralink wants to achieve)

Did I miss anything?

Sex, drugs, and rock n roll... ok , minus the rock music.

 

[Badger19]

Currently compiling a list for emerging tinnitus treatments. So far I have the following:

For tinnitus directly:
OTO-313 (Otonomy)
XEN1101 (potentially)
Lenire
University of Michigan Device
University of Minnesota Device
Visual Snow Device (maybe, potentially? awaiting more information from visual snow initiative on what this is about)

Hearing loss restoration:
FX-322 (Frequency)
CGF-166 (Genvec/Novartis)
LY3056480 (Audion/Regain)
OTO-6XX (Otonomy, further into the future)

Hidden hearing loss:
OTO-413

Potential treatments in the very far future:
Refined deep brain stimulation (what Neuralink wants to achieve)

Did I miss anything?

So... nothing for hyperacusis?

 

[JohnAdams]

CGF-166 (Genvec/Novartis)

Seriously, look into this. This requires that they surgically remove your eardrum, drill a hole in your cochlea with a laser, and then inject your cochlea with viral vectors containing ATOH1.

 

[Earing]

Seriously, look into this. This requires that they surgically remove your eardrum, drill a hole in your cochlea with a laser, and then inject your cochlea with viral vectors containing ATOH1.

I can't see how removing the eardrum would be a good thing.

 

[JohnAdams]

I can't see how removing the eardrum would be a good thing.

well, they reattach it, but yeah I'm with you.

 

[Earing]

well, they reattach it, but yeah I'm with you.

There is one of the 3 little bones attached to the eardrum on the inside.

 

[Sevv]

Seriously, look into this. This requires that they surgically remove your eardrum, drill a hole in your cochlea with a laser, and then inject your cochlea with viral vectors containing ATOH1.

Ah yeah, you're right. In addition, it seems mainly to be for severe to profound hearing loss. Means however this is the deafness cure if it works. And if it does, it will probably so important that they'll find a better way for administration... who knows?

 

[Lilah]

So... nothing for hyperacusis?

White noise generators, they have removed hyperacusis for some.

 

[GregCA]

There is one of the 3 little bones attached to the eardrum on the inside.

It's called the malleus.
It's possible to do an incision and move the ear drum out of the way and then reattach it after you've done what you wanted to do behind it.
I've had it done 3 years ago. My daughter had it done 3 months ago.
I've also had a hole drilled in my cochlea.
It's not a fun procedure.