Tinnitus Sedation with Botox, 82% success
I've been suffering from tinnitus from acoustic trauma. In addition, I experience jaw pain from clenching teeth due to the stress of tinnitus.
The very morning after I received masseter botox injections, I woke up with relief, wondering why it was so quiet! Shocking reduction in suicidal intrusive multi-tone tinnitus that's been resistant to treatment! Even silent moments without ambient noise during the day. Full effect is after 10 days. I had the lowest dose of 30-35 units, whereas the paper goes up to 100 units.
A 2018 paper with impressive outcomes after temporalis and masseter injections. 14 out off 17 with disabling tinnitus improved, of which 11 it completely disappeared, whatever the cause! That's 82% improved and 65% cured!
https://www.sciencedirect.com/science/article/pii/S0028377018300778
This is stronger than the previous 2005 paper with 3 injections to the ear... 7 out of 26 improved or 27%:
https://pubmed.ncbi.nlm.nih.gov/15944559/
According to Ca Ear Institute:
Q: How can BOTOX affect tinnitus? A: BOTOX is thought to decrease response in a neural pathway known as the autonomic nerve pathway. Stimulation of this pathway is what is thought to cause significant tinnitus irritation. Decreased activity in this pathway may subsequently decrease the tinnitus.
Sani Aesthetics in Los Gatos offers the temple and mandible injections for TMJ, but usually you'd go to a dentist, TMJ doctor or neurologist.
2018 PAPER:
Tinnitus sedation after botulinum toxin injection into the manducator muscles
https://doi.org/10.1016/j.neuchi.2018.05.010
Introduction
The treatment of bruxism by injection of the manducator muscles aims to reduce the tone of the temporals and masseters, requiring non-negligible amounts of botulinum toxin, accompanied by inevitable diffusion of the product. In a retrospective study carried out on a cohort of patients treated for bruxism, we observed remarkable efficacy of botulinum toxin in some of them with tinnitus, whatever the origin.
Material and methods
This is a retrospective study of 288 patients treated for bruxism in the same institution. All the patients were injected into the masseter and temporal muscles with botulinum toxin (Botox *: Allergan Pharmaceuticals, Westport, Ireland), the injected doses varying according to the intensity of the contractions observed between 30 and 100 U at the level of the masseter and between 10 and 50 U in the temporal muscle. The files were reviewed over a period of 2 years, between 2015 and 2016.
Results
Out of 288 files reviewed, 17 patients suffered from disabling tinnitus, resistant to any form of drug therapy. Fourteen saw their symptoms decrease (in 3 cases) or disappear completely (11 cases), with an effectiveness persisting at least until the following session (3 months).
Discussion
By their common innervation by the trigeminal nerve, neuromuscular dysfunction of the masticatory muscles could induce reflex hypertonicity of the muscles of the middle ear, as well as myoclonus of the palate resulting in tinnitus. Some of them could have a toxic origin, by excessive release of glutamate in the ear. N-methyl-D-aspartate (NMDA-Rs) receptors are located at each synapse of the auditory pathways, and are characterized by a slow response, with a long refractory period, after excitation by glutamate, allowing protection of the system in the event of a sound attack. An over-excitation beyond the possibilities of repair would be involved in the occurrence of hearing loss related to noise, presbycusis and the occurrence of tinnitus.
Conclusion
Our series is the first to demonstrate a possible effect, probably by inhibiting the release of glutamate, at the receptors of the inner ear. An open and prospective study, ideally multicenter, will be necessary to confirm the validity and the reproductive character of our results.