Fosfomycin or Amoxicillin for UTI? Which Is Safer for a Tinnitus Patient?

[javier massanet]

One year ago I had chronic prostatitis, and because of the many antibiotics that I took I produced clostridium difficile for which I was given vancomycin which gave me severe tinnitus.

I currently have faecalis UTI infection and I have to take one of the following antibiotics during 2 weeks: amoxicillin, ampicillin, imipenem, daptomycin, teicoplanin, linezolid, fosfomycin, nitrofurantoin, gentamicin or rifampicin.

What would be the least otoxic?

The last one I took was amoxicillin but I left it at four days in because the tinnitus became much stronger.

Is fosfomycin the best option for me?


Kind regards,
Javier
Mallorca (Spain)

 

[Bill Bauer]

Are you saying that your tinnitus got stronger after four days on amoxicillin? This is very strange, as it is supposed to be the safest antibiotic...

Neither of the two antibiotics that you mentioned appear on
http://hlaa-sbc.org/wp-content/uploads/2013/11/Ototoxic_Brochure.pdf

 

[Star64]

Do not take anything that ends in mycin or micin; these are extremely ototoxic, especially gentamicin, this drug is well known to cause hearing loss especially if given IV or in high doses... Amoxillicilin is usually safe but not that good a drug for certain UTI bacteria... do not take cipro or any quinoline antibiotics either, they have been known to cause havoc on central nervous system for some people.

Wishing you a speedy recovery

 

[JohnAdams]

Cranberry juice.

 

[linearb]

@javier massanet I haven't had any problems with Amoxicillin; we're all different.

However, in many cases "prostatitis" or "bacterial prostatitus" has nothing to do with bacteria and is actually a muscle tension problem. Oddly, antibiotics may temporarily help with the pain, because many of them have anti-inflammatory actions, but an Ibuprofen might do much the same.

If you really have a UTI, confirmed by culture, kill it. If you frequently have pain or discomfort in the region of your posterior and prostate -- I'd strongly recommend getting checkout out by a physical therapist who has specialized in pelvic floor dysfunction and knows how to treat it in men.

https://www.restorationspt.com/blog/pelvic-rehabilitation-visit-1-men/

Cranberry juice.

It's a common idea and they sell tablets and juice, but they don't actually seem to work very well; whatever effect exists is tiny tiny compared to what ABx do:

https://jamanetwork.com/journals/jama/fullarticle/2576822

Findings In this randomized clinical trial of 185 women nursing home residents, after adjusting for missing data and covariates, there was no statistically significant difference in presence of bacteriuria plus pyuria between the treatment (29.1%) and control (29.0%) groups over 1 year.

Meaning Among older women living in nursing homes, cranberry capsules, compared with placebo, did not have a significant effect on the presence of bacteriuria plus pyuria over 1 year.

https://www.cochrane.org/CD001321/RENAL_cranberries-for-preventing-urinary-tract-infections

the evidence that the benefit for preventing UTI is small, cranberry juice cannot currently be recommended for the prevention of UTIs.

https://www.iflscience.com/health-a...-urinary-infections-despite-what-youve-heard/

"We recognize that the majority of UTIs will require antibiotic treatment, but we need to be smarter with our use of these medicines," said Professor Mark Baker, director for the center of guidelines at NICE, in a statement.

It goes against the old wives' tale claiming that cranberry juice prevents or can treat UTIs – one that cranberry producers have spent millions promoting.