Frequency Therapeutics — Hearing Loss Regeneration

[JohnAdams]

deuce bag

 

[GlennS]

I think he was thinking of this.

 

[Daniel Lion]

That one Harvard researcher was saying that the nerves miraculously heal once the hair cell is regenerated. Though I agree the tinnitus is most likely more from the nerve damage, if it heals once the hair cell is back then it should improve too.

"Stanford"

 

[Mathieulh]

Sorry, I was just bitter over your comment about hoping the drug helps my high frequency hearing loss but could give a toss over people with profound hearing loss. Kind of hard not to interpret that comment any other way, but selfish and hurtful.

Ces't la vie.

I will be nice , and start again with peace in my heart. Peace to you, my feelings were hurt, it happens when you have chronic tinnitus and profound hearing loss.

Start again...

Don't get me wrong, I would love to see all types of hearing loss fixed with some miracle drug/cure, but even something that only restores high frequencies goes a long way into helping a lot of people, me included, I rather have that available than nothing at all.

 

[Daniel Lion]

Don't get me wrong, I would love to see all types of hearing loss fixed with some miracle drug/cure, but even something that only restores high frequencies goes a long way into helping a lot of people, me included, I rather have that available than nothing at all.

Cool... peace... let's work together.
Truce....
Sincerely, Daniel

 

[Jurger]

Don't get me wrong, I would love to see all types of hearing loss fixed with some miracle drug/cure, but even something that only restores high frequencies goes a long way into helping a lot of people, me included, I rather have that available than nothing at all.

It probably would, but it depends on what you mean by "high frequency". High frequency as in 8000-2000 Hz or >8000 Hz. I don't see a drug (partially) restoring frequencies that ENTs don't even test as a commercially viable drug. That is unless they can proof restoring those frequencies helps with word recognition or something.

 

[FGG]

It probably would, but it depends on what you mean by "high frequency". High frequency as in 8000-2000 Hz or >8000 Hz. I don't see a drug (partially) restoring frequencies that ENTs don't even test as a commercially viable drug. That is unless they can proof restoring those frequencies helps with word recognition or something.

If it improves clarity and tinnitus, my prediction is audiologists will start testing the >8000 Hz frequencies.

 

[Jurger]

If it improves clarity and tinnitus, my prediction is audiologists will start testing the >8000 Hz frequencies.

Maybe, but how long do you think it will take to implement that in ENT clinics worldwide? And even if it does help with tinnitus, what's the business case here? Hearing loss has a very well defined business case in terms of how much it costs governments and insurers. That's the attractive part of these drugs and why Frequency - if successful - can charge a premium. Tinnitus - frankly - doesn't have that, and I say that has someone who has it. The only thing I can think of are patients who don't have a job because their tinnitus is that bad, but have great hearing. But that's a small minority.

 

[FGG]

Maybe, but how long do you think it will take to implement that in ENT clinics worldwide? And even if it does help with tinnitus, what's the business case here? Hearing loss has a very well defined business case in terms of how much it costs governments and insurers. That's the attractive part of these drugs and why Frequency - if successful - can charge a premium. Tinnitus - frankly - doesn't have that, and I say that has someone who has it. The only thing I can think of are patients who don't have a job because their tinnitus is that bad, but have great hearing. But that's a small minority.

I don't think it would have to be implemented at every ENT but certainly every sub-specialist (otologist) should have this ability anyway.

 

[JohnAdams]

LOL if Frequency Therapeutics investors or employees are cruising this site and check on this thread about their company and see a huge douche pump.

 

[GlennS]

LOL if Frequency Therapeutics investors or employees are cruising this site and check on this thread about their company and see a huge douche pump.

Gee, and who, praytell, is responsible for that?

 

[Tom Soria]

Is there a chance that this future treatment might be able to help those of us with problems like hyperacusis, TTTS, hearing distortion? I have learned to live with tinnitus. I can cope with it fine but these other conditions are what make my life a living hell. This is what i really hope to find treatment for.

 

[Lucifer]

Is there a chance that this future treatment might be able to help those of us with problems like hyperacusis, TTTS, hearing distortion? I have learned to live with tinnitus. I can cope with it fine but these other conditions are what make my life a living hell. This is what i really hope to find treatment for.

Not too sure. From what I know someone who was on the Regain/Audion trial experienced improvements and could go on tour again. They never stated whether their hyperacusis or tinnitus improved but you would think to be able to go on tour again you must be able to cope with loud noise so I do think Regain/Audion works and Frequency Therapeutics could do the same as well.

 

[Gorbeh3]

Phase II Locations:

Fresno, California

Torrance, California

Colorado Springs, Colorado

Boca Raton, Florida

Sarasota, Florida

Tampa, Florida

Louisville, Kentucky

Omaha, Nebraska

Matthews, North Carolina

Winston-Salem, North Carolina,

Orangeburg, South Carolina

San Antonio, Texas

 

[Street Novelist]

Who's trying to get in to one of those trials? I noticed there's still a slim chance you get all four doses. It makes me hesitant to apply. Is this trial really going to take a year to complete?

 

[JohnK]

I'm in California, how do I apply to the clinical trial?

 

[ChrisBoyMonkey]

I'm in California, how do I apply to the clinical trial?

https://clinicaltrials.gov/ct2/show/NCT04120116
Scroll down to the locations, call the number to the location you are interested in. Which part are you in?

 

[JohnK]

Bay Area but why would I let that stop me?

 

[FGG]

Who's trying to get in to one of those trials? I noticed there's still a slim chance you get all four doses. It makes me hesitant to apply. Is this trial really going to take a year to complete?

I am attempting to. Worried I have some exclusions in my history though given my history of vertigo and normal 250-8000 Hz audiogram.

 

[ChrisBoyMonkey]

Bay Area but why would I let that stop me?

I was just wondering, in case I do it too, to see if we would go to the same location lol.

 

[tarmaced]

From the introduction:

"The importance of delivery cannot be understated;

Wait what.

 

[Jurger]

Who's trying to get in to one of those trials? I noticed there's still a slim chance you get all four doses. It makes me hesitant to apply. Is this trial really going to take a year to complete?

I believe what companies sometimes do is offer 'placebo patients' the full dose after the trial is concluded. You can at least ask them that beforehand.

 

[Lucifer]

When would patients start receive the first dose?

 

[F-u-T]

When would patients start receive the first dose?

They have already started dosing patients at some locations.

 

[Rb86]

I mentioned FX-322 to my ENT today. He said his co-worker at another location is running the trial in my area and offered to set up a meeting to discuss.

I'm technically not qualified as I have diagnosed hearing loss for only 4.5 months. (You need at least 6). But, we'll see.

I'm VERY cautious as I don't think I could emotionally handle getting worse.

 

[all to gain]

I mentioned FX-322 to my ENT today. He said his co-worker at another location is running the trial in my area and offered to set up a meeting to discuss.

I'm technically not qualified as I have diagnosed hearing loss for only 4.5 months. (You need at least 6). But, we'll see.

I'm VERY cautious as I don't think I could emotionally handle getting worse.

Wow, but a good chance to maybe see your tinnitus being cured.

Not sure what I would do if I had the chance. I think I would probably take it as I'm suffering big time, but I would still be very wary.

 

[Rb86]

Wow, but a good chance to maybe see your tinnitus being cured.

Not sure what I would do if I had the chance. I think I would probably take it as I'm suffering big time, but I would still be very wary.

The way I see it, IF this stuff's effective, we will all get our chance with it. But yes, I have to give it more thought, talk with them, etc.

 

[all to gain]

The way I see it, IF this stuff's effective, we will all get our chance with it. But yes, I have to give it more thought, talk with them, etc.

True, but you may be one of the lucky ones who gets it 5-10 years before anybody else. Of course, that's if it works, and more importantly, that's if it doesn't make things worse. But it's a chance that may well be worth taking. Lots of pros and cons to weigh up.

 

[ChrisBoyMonkey]

The way I see it, IF this stuff's effective, we will all get our chance with it. But yes, I have to give it more thought, talk with them, etc.

This stuff is supposed to help and already saw some good results, better than just safe, from phase 1. I'd give it a shot if I had the chance.

 

[Auron]

They have already started dosing patients at some locations.

Wow, someone's ears may be repairing themselves while I type this. Salvation may be around the corner.