I completely relate. Don't lose any sleep though, regeneration can only help. Restoring hair cells COULD help ear pain, it's just that science on hyperacusis isn't far along enough to know either way until we try it out.
Let me put it do you this way. Some time back in the 90's I was visiting an old friend of mine. Couch surfing may be something like what you'd call it today. But he had a one-roomed apartment with kitchen. I wanted to intrude as little as possible so I asked him could I roll out my sleeping-bag in his kitchen. Well the first night was cramped as there was not enough room -- I was lying diagonally trying to stretch out but couldn't do it fully. Next night I discovered that if I could open the press door at my head, that little bit extra room would allow me to place my head and stretch out. Next night I installed a pillow and could sleep OK all fine and dandy.
….Think of the miracle of hearing generation as one long delay.
I agree with most of what you're saying but can we PLEASE kill this attitude? There are scientists and all over the world doing research to better understand ear disorders and find cures. They work VERY hard and have a much clearer idea of what they're doing than we ever will. They want to go to market ASAP and I'm sure they're doing everything they can to make it happen. It's their job. They care about us!
You could call the numbers of those locations' trial information desks and ask. I'd actually like to know the answer as well. I understand the sense of urgency all too well and don't want any delays in this either.
Honestly, every angle by which I've analyzed Frequency Therapeutics' activities reveals they are moving as fast as they possibly can. The fact that Lucchino literally said the words BREAKTHROUGH THERAPY without any direct input from our community is incredibly heartening. These are big Stanford grads with big money behind them. They will have every asset at their disposal to ensure they get this to market ASAP, pending phase 2 success.
Agree. I have followed biotech for a decade and Frequency Therapeutics is on top of this at a level I rarely have observed. They are extremely motivated. Even getting this to the market as early as 2022 would be directly related to their dedication and drive. I really like Lucchino as a CEO. Actually I like the whole team for this job.
Cut me some slack please... I believe in this drug. I always have.
Yes same team and positive thoughts. I too also believe in FX-322 would work for us. They have already had successful candidates who had improvements in their word scores.
I know my Friend, I know. I have been here for a while and my ears are shot to shit. A massive ski slope with sudden hearing loss history. My tinnitus is relentless and loud. I have lost my work and my profession and much more.
Oh, I wasn't by any means targeting you. I was just injecting some certainty & positivity into your very realistic picture of scientific evolution =)
They will most likely do well in the clinical trials. Let's hope they receive as much help from the FDA to get FX-322 out in the market ASAP.
Cool... no worries. Fingers crossed friend.
Things could be released at the same time, depending on production and distribution.
It depends on who you ask but it seems strongly implied to me. For all the arguments back and forth, you might have to go digging through the last few months of posting on this thread.
You can get any treatment you want here if you are willing to pay for it out of pocket. No one will be able to tell you what that price will be at this point.
In a previous Q and A the question was asked about benefits seen in secondary endpoints (of which one is tinnitus); the reply was "We saw trends across the population." We can reasonably assume that a tinnitus reduction was reported by one or more subjects since it is unlikely that they would have added the TFI to the secondary outcome measures without expecting a benefit. Of course when phase 2a is unblinded the million dollar question will be answered.
The concentrations for phase 2a have not been made public. In fact, I even asked when I applied for the trial and she said could not say.
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