Yeah I came across this video before and I feel it's potentially slightly misleading as it's just going off the Phase 1 results which are based on a safety dose.
He's an audiologist as I recall, not an MD so his assessment seems largely based on the standard audiogram, which is pretty limited.
Serendipity gave a great rundown, but I thought I might add that one of the theories regarding noxacusis is that the damaged OHC are leaking ATP and therefore by repairing the culprit hair cells you can stop the A2 nerves from being stimulated.
It was me. She said that the word score results were "completely unprecedented."
It will help let you know if you have obvious OHC damage. In the high frequencies often people don't "notice" their hearing loss.
I'm sure you could still get a high-frequency audiogram, but as for me it just took a simple video like this one to determine my hearing is fucked in the high frequencies (especially in my right ear):
Dr. Cliff is a practicing, board-certified audiologist and an outstanding resource; his YouTube channel was a godsend when I started my hunt for hearing aids around the time I learned I had hearing loss and tinnitus. I saw the video around the time it came out and while I don't have the time right now to document it, I agree that it seemed as if he didn't do his homework quite as thoroughly as he could have on this one. That plus, rightly so, he can err on the side of conservative claims and doesn't want to create unrealistic expectations.
Thanks for the alternative!
They had mentioned it before but I'm not sure if they did it graphically. It was explained that people generally have normal word scores with mild hearing loss so that makes sense.
I wouldn't worry about the omission of ototoxic. I think he was just listing some of the major causes of hair cell loss.
Ahh. Perhaps I didn't catch that in a verbal explanation. Reading it in a regulatory submission makes it much more tangible.
Believe me, I hold onto that study, though the drug is not as widespread destructive as high dose Azithromycin.
Interestingly - doing this with a very good quality headset I can still hear the 18kHz with ease. Of course this test isn't the most reliable either. I know it's not my tinnitus tone because that isn't that high in frequency. I'm 23. Shrug.
Yeah I can hear up to 18kHz as well, in my left ear. I listened to & made loud music, played videogames loudly, and shot guns unprotected throughout my childhood.
You mentioned neck issues in another thread. Sometimes physical therapy can really help with tinnitus if it's related. Have you tried it?
I am currently in physical therapy yes, but due to the current state of the world I've only been able to get one in-person session. I've been doing some stretches for a month, though, and it does seem that the wildest fluctuations are beyond me at this point - which means something is improving. It's really stiff though, so it's going to take some time before I expect real improvement. I need to be more patient but unfortunately that's not one of my best qualities.
Lol you definitely have a LOT more loud noise exposure than me it seems. I always kept my music fairly quiet, especially on headphones. I can hear frequencies this well in both ears btw.
Haha yeah seems like it! My right ear only can hear up to 9kHz.
If the person under stress has hair cell damage then yes it will help them.
Synapses, nerve or brain stem cannot be affected by damage (oxidation) due to stress?
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