If there was good data and FDA allowed them to market their drug, I guess shares would increase significantly, because it would be the first drug for inner ear applications on the planet.
I'm hoping this is the case. If this drug fails, it might be a while before other companies try to treat hearing loss. There's a chance if this doesn't work, other companies might try to bypass the ear altogether before we get actual hearing regeneration.
I hope the audiologist is right! But there's really no way for anyone to know at this point. I totally agree about the feeling of dread... I still remember how my heart sank the day the OTO-313 results came out.
I saw an ENT who told me OTO-313 was a success. He even saw it fixing people's tinnitus but then it was a total failure. Just be extra careful hoping for too much with FX-322.
I think the odds are 50/50 - a coin flip basically. On one hand Phase 2a failed, along with several of their other Phase 1b trials. Insanity is doing the same thing over and over again and hoping for different results.
If any of FX-322/FX-345 work and get to market, I believe they will only work to a limited extent. It could be something like a 60% chance of reducing your tinnitus by 40%.
I think they avoid the word cure because it's only a small hearing improvement and won't go back to 100%.
That's where FX-345 could improve on, but yeah, those with severe hearing loss will be left in a lurch for a while. But I'm hoping it can restore 40 percent of their hearing back.
From the data we've seen in the previous studies, for those with moderately-severe hearing loss, FX-322 won't restore 40% of their hearing. At best it will help them with word clarity - giving those people 10-20% better clarity in word recognition (with a few people being super responders and having bigger improvements). It has not been shown to help with improving audiogram scores. It's been theorized that this may be because FX-322 is regenerating inner hair cells (IHCs), which deal with word clarity. Outer hair cells (OHCs) deal with amplifying sound.
Absolutely! The most difficult thing is showing it's possible and achievable! If they manage to regenerate working hair cells, it could quite possibly be one of the biggest scientific discoveries of our lifetime. I have everything crossed for this study going well!
The economy was roaring I will give you that, but FREQ was an over priced play that fell when investors found out this wasn't a get rich quick scheme. Hypothetically, the share will rise to that of its actual value, which with an effective drug should be somewhere around $20-$100 a share. I mean the way they are setting themselves up, they will have the only effective drug on the market resulting in having complete control of the market.
There's nothing new in it.Could someone post a summary? I can't get subtitles in my language
Thank you.
I think there are some apps out there that can translate the subtitles. Do a Google search or check your app store.Could someone post a summary? I can't get subtitles in my language
Thank you.
Yep. It's mostly an attempt to put a positive spin on results that are, at best, mild.
Any early treatment will be mild.
If there is proof of regeneration, that would be fantastic and the first time in a human cochlea.
Whether they had good results, or terrible results, the pitch would look exactly the same.
In an ideal world, yep.
Member
